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Smart Reasoning:

C&E

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Causes

Effects

the mutationcausesreduced activity of the enzyme

/ III deficiencycausesreduced activity of the enzyme

Glu429Alacausereduced activity of the enzyme

Point mutationscausingdecreased activity of the enzyme

pH(passive) is influenced byEnzyme Activity Enzyme action

The 50 % presence of the R309Q PHKG2 mutant subunitcausedcomplete inhibition of PhK enzyme activity

the reactionleadingto dilution of metabolic enzyme

the cell(passive) is influenced byactivity of an enzyme

these two mutationsresultedin greater residual enzyme activity

treatmentcan causeundetectable level of enzyme activity

A single nucleotide polymorphism of the MTHFR gene C677 Tcausesreduction in enzyme activity

The F219V substitutioncausesreduction in enzyme activity

This mutationmight causereduced enzyme activity

expressionindeed ledto reduced enzyme activity

an increasing substrate concentrationinfluencesthe rate of an enzyme activity

temperature(passive) is influenced byThe rate of enzyme activity

the use of growth - inhibiting concentrationsprovokedinhibition of the enzyme activity

Accumulation of Product in a reactioncausesinhibition of enzyme activity

product accumulationmight causeinhibition of enzyme activity

product accumulationmay causeinhibition of enzyme activity

The Asian - specific single nucleotide polymorphism rs671causesreduced enzyme activity

Excess substratecausesinhibition of enzyme activity

The TPMT gene ... identifiedcausingdecreased enzyme activity

several functional polymorphismscausingdecreased enzyme activity

several single nucleotide polymorphisms ( SNPs ) identifiedcausingdecreased enzyme activity

G allelecausesdecreased enzyme activity

ATPasecausinginhibition of the enzyme activity

A allelecausesdecreased enzyme activity

CYP2D6 * 10 ( * 10causesdecreased enzyme activity

by mutations in encode sequences 2(passive) caused byDecreased enzyme activity

an inherited defect in the UROD genecausingdecreased enzyme activity

different factorsinfluencingthe variability in enzyme activity

which mutationleadsto diminished enzyme activity

Factorsinfluencingextracellular enzyme activity

Contents 1 Factorsinfluencingextracellular enzyme activity

Mutationsleadingto residual enzyme activity

mutationsmay resultin residual enzyme activity

mutationsresultin residual enzyme activity

different gene mutations(passive) caused byresidual enzyme activity

other pathogenic variantsresultingin some residual enzyme activity

to arrest of DNAleadsto arrest of DNA

to arrest of DNA synthesis and cell deathleadsto arrest of DNA synthesis and cell death

star activitycan causestar activity

to collagen defectscan leadto collagen defects

to bone marrow toxicity and/or discontinuation of treatmentcan leadto bone marrow toxicity and/or discontinuation of treatment

to increased fluxleadsto increased flux

to the production of HDL cholesterolcontributesto the production of HDL cholesterol

in fewer carbs being broken down into simple sugars allowing blood sugar to stay more stableresultsin fewer carbs being broken down into simple sugars allowing blood sugar to stay more stable

uncompleted digestioncausesuncompleted digestion

in increased concentrations of haloperidolmay resultin increased concentrations of haloperidol

uncompleted digestion and sending undigested food to the colon to ferment to cause toxins and colon pocketscausesuncompleted digestion and sending undigested food to the colon to ferment to cause toxins and colon pockets

to increased drug levels and toxicitypossibly leadingto increased drug levels and toxicity

to reduced clearance , resulting in a lower therapeutic doseleadsto reduced clearance , resulting in a lower therapeutic dose

in milder or no features of galactosemia such as the Duarte variant ( GALT gene mutation).Diagnosticresultingin milder or no features of galactosemia such as the Duarte variant ( GALT gene mutation).Diagnostic

to the accumulation of desmosterol and a lack of cholesterol , disrupting antenatal and postnatal developmentleadsto the accumulation of desmosterol and a lack of cholesterol , disrupting antenatal and postnatal development

impaired re - methylationcausingimpaired re - methylation

to the build up of acetaldehydeleadingto the build up of acetaldehyde

the phenotypescausingthe phenotypes

in decreased production of nitric oxide and a decreased ability to vasodilate , which can result in high blood pressurecan resultin decreased production of nitric oxide and a decreased ability to vasodilate , which can result in high blood pressure

in decrease of serum LDL levelsresultingin decrease of serum LDL levels

to degradationcan leadto degradation

to uncontrolled tumor growthleadsto uncontrolled tumor growth

in risk stratification of subjectscan contributein risk stratification of subjects

to slow progression of the diseasemight leadto slow progression of the disease

alterations in the metabolic clearance of the substrate drugmay causealterations in the metabolic clearance of the substrate drug

from microorganisms actively growing in a culture mediumresultingfrom microorganisms actively growing in a culture medium

in slightly less severe phenotypesresultin slightly less severe phenotypes

to slow progression of the disease and result in the so - called cardiac or renal variants with delayed presentationmight leadto slow progression of the disease and result in the so - called cardiac or renal variants with delayed presentation

in risk stratification of subjects with variant ACADM genotypescan contributein risk stratification of subjects with variant ACADM genotypes

in fatigueresultsin fatigue

to an increase in the half - life of calcitriolleadingto an increase in the half - life of calcitriol

Smart Reasoning:

C&E

See more*