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Qaagi - Book of Why

Causes

Effects

by a failure of the bone marrow to generate enough red blood cells(passive) is caused byBlackfan - Diamond anemia ( BDA

a failure of the bone marrow to generate enough red blood cells(passive) is caused byBlackfan - Diamond anemia ( BDA

by a failure of the bone marrow to generate enough red blood cells(passive) is caused byBlackfan Diamond Blackfan - Diamond anemia ( BDA

deficiency of B12 , folicacid or bothB12 deficiency due to dietary deficiency(passive) caused byMEGALOBLASTIC ANEMIASMacrocytic anemia

mutationsresultingin Diamond - Blackfan anemia

mutations(passive) can be caused byDiamond - Blackfan anemia

GATA1 mutationsresultingin Diamond - Blackfan anemia

Mutations in other ribosomal protein genescan causeDiamond - Blackfan anemia

mutations in the ribosomal protein genes(passive) is caused byDiamond Blackfan anemia

mutations in several genes , some of which have been identified and some of which have not(passive) is caused byDiamond - Blackfan anemia

mutations in ribosomal proteinscauseDiamond - Blackfan Anemia

identifies mutationsresultingin Diamond - Blackfan anemia

Mutation of ribosomal protein RPS24 inresultsDiamond - Blackfan anemia

Mutations affecting genes encoding ribosomal proteinscauseDiamond Blackfan anemia

Exome Sequencing Identifies GATA1 MutationsResultingin Diamond - Blackfan Anemia

A deficiency of riboflavincausesnormocytic normochromic anemia

by RPS19 affecting 40S ribosomal subunit maturation(passive) caused byDiamond - Blackfan anemia

RPS19 affecting 40S ribosomal subunit maturation(passive) caused byDiamond - Blackfan anemia

vitamin B6 deficiency from a low iron intake(passive) may be caused byHypochromic anemia

vitamin B6 deficiency from a low iron intake(passive) may be caused by Hypochromic anemia

by vitamin B6 deficiency from a low iron intake(passive) may be caused byHypochromic anemia

by Iron deficiency from a low Iron intake(passive) may be caused byHypochromic Anemia

iron deficiency from a low iron intake(passive) may be caused byHypochromic anemia

iron deficiency from a low iron(passive) may be caused byHypochromic anemia

a vitamin - B6 deficiency(passive) can be caused byHypochromic anemia

vitamin B6 deficiency(passive) may be caused byHypochromic anemia

by iron deficiency , thalassemia , sideroblastic anemia , and lead poisoning(passive) can be caused byhypochromic anemia

iron deficiency , thalassemia , sideroblastic anemia , and lead poisoning(passive) can be caused byhypochromic anemia

mutations in various genes(passive) can be caused byFanconi anemia

by bone marrow failure(passive) caused byaplastic anemia Anemia

mutations(passive) can be caused byFanconi Anemia

iron deficiency(passive) may be caused byHypochromic anemia

mutations in the BRIP1 gene(passive) caused byFanconi anemia

the genescauseFanconi anemia

biallelic mutations in the FANCM genecausedFanconi anemia

Heavy periods in women and gastric bleeding due to ulcerscan also causehypochromic anemia

mutations in several different genes including BRCA2(passive) can be caused byFanconi Anemia

mutations in several different genes including BRCA2.(passive) can be caused byFanconi Anemia

by deficiency of Fancd2 than Fancg(passive) caused byFanconi anemia

a recessive genecausesFanconi anemia

problems with ribosomal functionto causeproblems with ribosomal function

to severe anaemia , macrocytosis , and an increased risk of leukaemialeadsto severe anaemia , macrocytosis , and an increased risk of leukaemia

in an abnormally short , nonfunctional RPS10 protein that may impair the assembly of ribosomesto resultin an abnormally short , nonfunctional RPS10 protein that may impair the assembly of ribosomes

Rps26(passive) are causedRps26

congenital heart defects(passive) caused bycongenital heart defects

congenital heart defects(passive) caused bycongenital heart defects

the reduced levels of a protein known as Rps26(passive) are caused bythe reduced levels of a protein known as Rps26

the reduced levels of a protein known as Rps26(passive) are caused bythe reduced levels of a protein known as Rps26

to bone marrow failure and cancercan leadto bone marrow failure and cancer

bone marrow failure , as well as different cancerscausesbone marrow failure , as well as different cancers

bone marrow failurecausesbone marrow failure

to bone marrow failureleadsto bone marrow failure

bone marrow failureeventually causesbone marrow failure

to serious complications such as bone marrow failure , which happens when the bone marrow stops making as many blood cellscan leadto serious complications such as bone marrow failure , which happens when the bone marrow stops making as many blood cells

to leukemia and other cancerscan leadto leukemia and other cancers

his bloodledhis blood

symptoms in patients with chronic renal failureis causingsymptoms in patients with chronic renal failure

cytogenetic instabilitycausescytogenetic instability

from a deficiency of the hormone erythropoietin from kidney failureresultsfrom a deficiency of the hormone erythropoietin from kidney failure

to absent or reduced protein functionleadto absent or reduced protein function

in potentially fatal cancers , such as leukemia and head and neck cancersfrequently resultsin potentially fatal cancers , such as leukemia and head and neck cancers

due to blood losscauseddue to blood loss

in low MCHCcommonly resultsin low MCHC

spleen growthcausesspleen growth

due tois causeddue to

from FANCC and FANCG mutationsresultingfrom FANCC and FANCG mutations

abnormal skin pigmentation , abnormal thumbs , smaller eye size , and short staturecan causeabnormal skin pigmentation , abnormal thumbs , smaller eye size , and short stature

to pica ( a condition in which the patient feels craving or the non - food items like paper , paint , dirt etccan leadto pica ( a condition in which the patient feels craving or the non - food items like paper , paint , dirt etc

to end - organ ischemia and infarctionleadingto end - organ ischemia and infarction

red blood cell destruction giving signs of anaemiacausingred blood cell destruction giving signs of anaemia

breast cancer if patients lived long enough , D'Andrea discovered.2 Five Fanconi anemia genes encode proteins that form a cluster that activates a sixth protein , which in turn activates another protein that bindswould ... causebreast cancer if patients lived long enough , D'Andrea discovered.2 Five Fanconi anemia genes encode proteins that form a cluster that activates a sixth protein , which in turn activates another protein that binds

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