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in particular(passive) has been discoveredCRISPR - Cas93
The patent issue ... the firstto inventCRISPR technology
Chinadid ... discoverCRISPR technology
in 2012(passive) was inventedCRISPR technology
less than four(passive) was inventedCRISPR technology
three years ago(passive) was inventedCRISPR technology
just three years ago(passive) was inventedCRISPR technology
less than four years ago(passive) was inventedCrispr technology
spacer ... a sequence in a putative ORF in the chromosomeshould causeCRISPR " autoimmunity
naturehas already designedanti - CRISPR
by Emmanuelle Charpentier and Jennifer A. Doudna(passive) discovered byCrispr / Cas9
by Jennifer Doudna , a UC Berkeley professor of biochemistry and molecular biology(passive) was ... discovered byCRISPR - Cas9
by UC Berkeley professor of biochemistry and molecular biology Jennifer Doudna(passive) was ... discovered byCRISPR - Cas9
Dr. Jennifer A. Doudna of UC Berkeley helpeddiscoverCRISPR - Cas9
Doudna and her collaborator , Emmanuelle CharpentierinventedCRISPR / Cas9
by jennifer doudna and Emanuelle Charpentier(passive) discovered bycrispr / Cas9
of single - molecular guide RNA(passive) is composedCRISPR - Cas9
by Jennifer Doudna(passive) invented byCRISPR - Cas9
The researchersdesignedCRISPR - Cas13b
by the two researchers(passive) discovered byThe Crispr / Cas9
by the ninth author , Jennifer Doudna(passive) invented by CRISPR - Cas9
by the ninth author , Jennifer Doudna(passive) invented byCRISPR - Cas9
of two components , Cas9 and a gRNA(passive) is composedCRISPR / Cas9
she and CharpentierinventedCrispr / Cas9
as an immune sequence in bacteria and archaea(passive) was discoveredCRISPR / Cas9
first(passive) was ... discoveredCRISPR / Cas9
an investigation ( interference proceeding ... the firstto inventCRISPR - Cas9
The development of a powerful genome editing tool in 2012has ledCRISPR / Cas9
The development of a powerful genome editing tool in 2012ledCRISPR / Cas9
in bacteria(passive) was discoveredCRISPR - Cas9
as a prokaryotic immunity - like system in bacteria(passive) was discoveredCRISPR / Cas9
co -discoveredCRISPR / Cas9
in 2012(passive) was discoveredCRISPR - Cas9
as a key component of prokaryotic adaptive immune systems(passive) was initially discoveredCRISPR / Cas
first(passive) was ... discoveredCRISPR - Cas14
Jennifer Doudna , a biologist at the University of California at Berkeley ... the first researchersto discoverCRISPR
the scientistinventedCRISPR - Cas9
Jennifer Doudna , a UC Berkeley biochemist who was part of the research teamdiscoveredCRISPR
to claiminventedCRISPR - Cas9
in 2013(passive) was discoveredCRISPR - Cas9
the way with genome editingcan leadthe way with genome editing
starhave discoveredstar
to additional studies involving human embryosmay leadto additional studies involving human embryos
mutations and large genetic rearrangements such as DNA deletions and insertionscausedmutations and large genetic rearrangements such as DNA deletions and insertions
substantial mutations in addition to significant genetic rearrangements like insertions and DNA deletions in the cellswas ... causingsubstantial mutations in addition to significant genetic rearrangements like insertions and DNA deletions in the cells
extensive mutations including large genetic rearrangements such as DNA deletions and insertionscausedextensive mutations including large genetic rearrangements such as DNA deletions and insertions
extensive mutations like DNA deletions and insertionscausedextensive mutations like DNA deletions and insertions
its proprietary CRISPR - Cas9 gene - editing technologywill contributeits proprietary CRISPR - Cas9 gene - editing technology
its proprietary CRISPR - Cas9 gene - editing technology and intellectual propertywill contributeits proprietary CRISPR - Cas9 gene - editing technology and intellectual property
extensive mutations ... but at a greater distance from the target sitecausedextensive mutations ... but at a greater distance from the target site
its proprietary CRISPR - Cas9 gene - editingwill contributeits proprietary CRISPR - Cas9 gene - editing
hundreds of unintended mutations in the genomecausedhundreds of unintended mutations in the genome
unintended off - target mutationsmay causeunintended off - target mutations
to unintended mutations in a genomecould leadto unintended mutations in a genome
to unintended mutations in a genomecan leadto unintended mutations in a genome
hundreds of off - target mutationsdidn?t causehundreds of off - target mutations
its proprietary CRISPR - Cas9 gene - editing 6will contributeits proprietary CRISPR - Cas9 gene - editing 6
unexpected genome changescausesunexpected genome changes
extensive mutations ... though at a distance from the target sitecausedextensive mutations ... though at a distance from the target site
in hundreds of unexpected mutationscan resultin hundreds of unexpected mutations
hundreds of unexpected mutationscould causehundreds of unexpected mutations
unwanted mutations in other areas of the genomecould causeunwanted mutations in other areas of the genome
mosaic mutations and off - target effects in various plantscausesmosaic mutations and off - target effects in various plants
to the double strand break of the target sitecan leadto the double strand break of the target site
unexpected mutationscausesunexpected mutations
a change in the DNA of the genomecausesa change in the DNA of the genome
gene - editing stocks lower after new studies published by Nature Medicine found that cells whose genomes are edited with the CRISPR - Cas9 technology have the potential to cause cancerledgene - editing stocks lower after new studies published by Nature Medicine found that cells whose genomes are edited with the CRISPR - Cas9 technology have the potential to cause cancer
The DNA changes(passive) caused byThe DNA changes
off - target effects(passive) caused byoff - target effects
unintended mutationsmay causeunintended mutations
to unintended mutationscan leadto unintended mutations
other powerful , precise genome editing toolshave ledother powerful , precise genome editing tools
extensive mutationscausedextensive mutations
extensive mutationscan frequently causeextensive mutations
Efforts(passive) are being led byEfforts
to repair DNAdesignedto repair DNA
more damage in the genome than thoughtcausesmore damage in the genome than thought
mutationscan causemutations
alsoledalso
DNA(passive) caused byDNA