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Smart Reasoning:

C&E

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Qaagi - Book of Why

Causes

Effects

these receptorscan influencetumor growth , vascular angiogenesis , and progression of cancer

these receptorscan influencetumor growth , vascular angiogenesis and the progression of cancer

inflammatory factorscontributeto tumor angiogenesis , growth and metastasis

a capacityto influencetumor angiogenesis , growth and metastasis

targeting tumor vasculatureleadingto reduced tumor angiogenesis and tumor growth

Overexpression of MMPsgreatly influencesthe growth , infiltration and metastasis of tumor

in turnleadsto decreased tumor angiogenesis and tumor growth

M2 macrophages are knownto ... contributeto tumor growth via angiogenesis and immunosuppression

pro - inflammatory cyclo - oxygenase-2 ( COX-2 ) expressionleadingto decreased tumor angiogenesis and tumor growth

We previously have showncontributedto tumor - induced angiogenesis and tumor growth

Western dietscausedincreased tumor growth and metastasis

class fermentationcontributeto the fungal growth and tumor growth

Besides direct stimulatory functions through secretion of growth factors or proteolytic enzymes , glioma infiltrating macrophages were also foundto contributeto tumor vascularization and net tumor growth

The TME is thoughtto influencetumor growth , metastasis , and , ultimately

Researchers ... more likelyto contributeto tumor growth , progression and metastasis

and VEGFleadingto increased vascularization and tumor growth

can lead to endothelial changes , multiplication and spreadleadingto tumor angiogenesis and tumor growth

multiple genetic alterations ... ( 1influencetumor growth , progression , and metastasis

a variety of cytokines and growth factors that are knownto influencetumor growth , metastasis and angiogenesis

This mutation ... the MET tyrosine kinaseleadsto enhanced tumor growth and metastasis

that bonecontributeto tumor growth , angiogenesis , and metastasis

excess ironcan contributeto tumor initiation and tumor growth

cascadescontributeto tumor growth , angiogenesis , and metastasis

MDSCs and TAMscontributeto tumor growth , malignancy , metastasis and stemness

the major factorcausingsuppression of tumor growth and metastasis

Dysregulation of c - Met / HGF signaling pathway affects cell proliferation , survival and motilityleadingto tumor growth , angiogenesis , and metastasis

RAS activationcan influencecarcinogenesis and tumor growth

processescontributeto tumor growth , invasiveness and metastasis

HGFcan leadto tumor growth , invasiveness , and metastasis

the factorscontributeto tumor growth , vascularization and metastasis

tumor microenvironment and locationinfluencetumor growth and metastasis

proteins inside the cellcan causetumor growth and metastasis

Tissue - specific expression of particular chemokinesalso influencestumor growth and metastasis

MSC ... tumor associated fibroblast in tumor microenvironmentinfluencestumor growth and metastasis

a number of cell types , including mesenchymal stem cells ( MSCs ) , cancer - associated fibroblasts ( CAFs ) , adipocytes , endothelial and immune cells , all of which ... have been shownto influencetumor growth and metastasis

several mechanisms by whichcan ... influencetumor growth and spread

researchers ... the factors they secretecan influencetumor growth and metastasis

a number of cell types , including mesenchymal stem cells ( MSCs ) , cancer - associated fibroblasts ( CAFs ) , adipocytes , endothelial and immune cells , all of which ... have been shown ... [ 8to influencetumor growth and metastasis

the formation of new blood vesselscausetumor growth and metastasis

the underlying molecular mechanismscausetumor growth and metastasis

to the investigation of HIF-1 alpha as a pharmacological targethas ledto the investigation of HIF-1 alpha as a pharmacological target

to apoptosis in ovarian most cancers cellsleadsto apoptosis in ovarian most cancers cells

to the identification of signaling growth pathways as targets for these directed therapieshas ledto the identification of signaling growth pathways as targets for these directed therapies

to apoptosis in ovarian most cancers cellsleadsto apoptosis in ovarian most cancers cells

to disease progressioncontributesto disease progression

to inhibition of osteoblastleadingto inhibition of osteoblast

from prolonged expression of VEGFcan resultfrom prolonged expression of VEGF

Nelson 's syndrome(passive) is causedNelson 's syndrome

in a 4.8 times higher incidence of cancerresultsin a 4.8 times higher incidence of cancer

in a 4.8 times higher incidence of cancer mortalityresultsin a 4.8 times higher incidence of cancer mortality

in poor survival in a mouse modelresultingin poor survival in a mouse model

cancer recurrence and patient survivalcould influencecancer recurrence and patient survival

Stent dysfunction(passive) mainly caused byStent dysfunction

the response of tumors to therapiessignificantly influencethe response of tumors to therapies

from a decrease in HIF-1alpha stability through S6K1 inhibition in combination with an H2O2-scavenging effectmay resultfrom a decrease in HIF-1alpha stability through S6K1 inhibition in combination with an H2O2-scavenging effect

to cancercan leadto cancer

this coughcan causethis cough

dry coughcan causedry cough

to the development of cancerleadto the development of cancer

cancercausecancer

apparent tumor shrinkage and may alter tumor morphologycauseapparent tumor shrinkage and may alter tumor morphology

to the induction of apoptosisleadingto the induction of apoptosis

to the decrease in metastasis in these wild - type p53 cellscontributedto the decrease in metastasis in these wild - type p53 cells

by signaling from the excess of HER2 proteinis causedby signaling from the excess of HER2 protein

hormonal changes(passive) caused byhormonal changes

to recurrence and metastasisleadingto recurrence and metastasis

to cancer progressionleadingto cancer progression

in DGR and finally GER , or the intra - abdominal pressure increases with the increasing volume of the tumorresultsin DGR and finally GER , or the intra - abdominal pressure increases with the increasing volume of the tumor

to development of therapeutic treatmentsleadingto development of therapeutic treatments

to worse cancer survivalleadingto worse cancer survival

to decreased survivalleadsto decreased survival

to cancer progressionleadingto cancer progression

in metastasisdoes ... resultin metastasis

a peritoneal effusion(passive) caused bya peritoneal effusion

significant brain swellingcausedsignificant brain swelling

occlusions(passive) caused byocclusions

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Smart Reasoning:

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