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non - allelic homologous recombination eventscausingcopy number variation and disease
this gene ... unlikelyto causevariation in cell number
This instabilitycausesvariation in gene copy numbers
a diseasecausingcopy number variation ( CNV ) ( 2
by structural variation(passive) caused bythe phenotypic variances ... ( i.e. copy number variation
the origin of replication with in the plasmid(passive) is influenced byCopy numbers Plasmid copy number
A robust method ... to discovercopy number variation from short sequencing
A robust methodto discovercopy number variation from short
by the events(passive) caused bycopy - number change
genetics researchershave discoverednumerous copy number variations
the process of transformation itselfcould be contributingcopy number changes
diseasecausingcopy number changes
the identification of diseasecausingcopy number changes
to unique genomic sequences in the reference genome assembly(passive) are designedCopy Number Reference Assays
a diseasecausingcopy number variation ( CNV
And ratio of share and ratio of national grant aid are appearedto influenceratio of variation
Genomic instabilityresultingin copy number variation ( CNV
the transformation process itselfresultsin rDNA copy number variation
we have been developingto discovercopy number variations ( CNV
Some multigene families undergo expansion and contraction ,leadingto copy number variation ( CNV
worlddiscovercopy variation
which is made use ofto setcopy numbers
The elevated plasmidmay resultcopy numbers
many gene gain and loss eventshave causedcopy number variation
the mechanismscausecopy number variation
either the duplication or deletion of a gene segment within a given chromosome(passive) is caused byCopy number variation
by insertion of sequence(passive) caused bycopy number variation
The polymorphismresultsfrom copy number variation
in humans(passive) has been discoveredcopy number variation
two different ways in whichresultedin copy number variation
their amplification(passive) caused bythe copy number variation
Genomic instabilityresultingin copy number variation
repeat is virtually the sameleadingto copy number variation
chromosomal instability with genomic gains or lossesresultin copy number variation
As functional alterations in mtDNAcan ... resultfrom copy number variation
functional alterations in mtDNAcan ... resultfrom copy number variation
by single genes(passive) caused bycopy number variations
The other class of possible mechanisms that are hypothesizedto leadto copy number variations
n+1 repeat is virtually the sameleadingto copy number variation
The last mechanismcan leadto copy number variations
in changes in protein expression for some of the patientsmight ... resultin changes in protein expression for some of the patients
gene haploinsufficiency or over - expression that can lead tocausinggene haploinsufficiency or over - expression that can lead to
to clinically relevant alterations in gene expressioncan leadto clinically relevant alterations in gene expression
to false discoveriesleadingto false discoveries
disease susceptibilityinfluencesdisease susceptibility
in the duplication or deletion of a generesultin the duplication or deletion of a gene
to diseasecontributesto disease
to the variation observed between individualscontributesto the variation observed between individuals
to genome variabilitycontributeto genome variability
in subtle differences in genomic background , which can lead to phenotypic variabilityresultin subtle differences in genomic background , which can lead to phenotypic variability
to cancer susceptibilitycan contributeto cancer susceptibility
significantlycontributesignificantly
inherited disease in the absence of coding - sequence alterationscould causeinherited disease in the absence of coding - sequence alterations
to human diseases and phenotypescontributeto human diseases and phenotypes
or may increase risks of various critical disorders.[1may causeor may increase risks of various critical disorders.[1
to variable degrees of fitness and/or disease predispositioncan contributeto variable degrees of fitness and/or disease predisposition
to natural genetic variation within and between populationscontributes significantlyto natural genetic variation within and between populations
significantlycontributessignificantly
to the ' missing heritabilitymight contributeto the ' missing heritability
to cancer pathogenesis , patient prognosis and therapeutic responsecontributeto cancer pathogenesis , patient prognosis and therapeutic response
to human lifespanmay ... contributeto human lifespan
in extreme early onset diseasesmay resultin extreme early onset diseases
to the missing heritability of obesitymight contributeto the missing heritability of obesity
the vernalization gene expression and showed little effect on the phenotypeinfluencedthe vernalization gene expression and showed little effect on the phenotype
from either copy loss ( microdeletion ) or copy gain ( microduplication ) of a genomic segmentresultingfrom either copy loss ( microdeletion ) or copy gain ( microduplication ) of a genomic segment
to variation in drug responsecontributesto variation in drug response
to disease susceptibilitycontributesto disease susceptibility
gene dosage ... which can result in altered gene expression and potentially cause genetic diseasescan ... influencegene dosage ... which can result in altered gene expression and potentially cause genetic diseases
significantly to the genetic architecture of human obesitycontributessignificantly to the genetic architecture of human obesity
disease relevant genes(passive) influenced bydisease relevant genes
to the genetic architecture of human obesitycontributesto the genetic architecture of human obesity
in reduced gene dosage due to any loss - of - function mutationresultsin reduced gene dosage due to any loss - of - function mutation
the expression of +can influencethe expression of +
to risk of ' schizophreniacontributeto risk of ' schizophrenia
gene expression and metabolic traitsinfluencesgene expression and metabolic traits
human phenotypescan influencehuman phenotypes
in altered phenotypic reactionresultedin altered phenotypic reaction
Gene expression change(passive) caused byGene expression change
to susceptibilitymay contributeto susceptibility
experimental variability(passive) caused byexperimental variability