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Smart Reasoning:

C&E

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Qaagi - Book of Why

Causes

Effects

the chemicalcausesjaundice to occur ( Bilirubin

However , an underdeveloped liver can not filter out the bilirubin as fast as it is being producedresultingin hyperbilirubinemia ( an excess of bilirubin

any drugcausingBILIRUBIN CONJUGATED INCREASED

other drugscauseBILIRUBIN CONJUGATED INCREASED

THERAPYcausesBILIRUBIN CONJUGATED INCREASED

an autosomal recessive disordercausesan increase of conjugated bilirubin

2.Initiallycausesan increase in conjugated bilirubin

> Viral hepatitiscan also causesthe rise in conjugated bilirubin

Viral hepatitiscan also causethe rise in conjugated bilirubin

Viral hepatitiscan also causesthe rise in conjugated bilirubin

by jaundice(passive) caused byneonatal bilirubin encephalopathy

Decreased uridine - diphosphoglucuronate glucuronosyltransferase ( UDPGT ) activityleadsto decreased conjugation of unconjugated bilirubin

Excessive unconjugated bilirubin levels ... enzyme deficiencyresultsin impaired conjugation of bilirubin

hyperbilirubinemia?Whatcausesimpaired bilirubin conjugation in unconjugated

Unconjugated hyperbilirubinemiamight resultfrom impaired conjugation of bilirubin

Unconjugated hyperbilirubinemiamay resultfrom impaired conjugation of bilirubin

is reported to displace bilirubin from albumin binding sitespotentially causingbilirubin encephalopathy

reported to displace bilirubin from albumin binding sitespotentially causingbilirubin encephalopathy

severe jaundicecausingbilirubin encephalopathy Bilirubin encephalopathy ( BE

displace bilirubin from albumin binding sitespotentially causingbilirubin encephalopathy

which is conjugated with a glucuronie molecule in the liverresultingin conjugated ( direct ) bilirubin

who are premature because ceftriaxone is reported to displace bilirubin from albumin binding sitespotentially causingbilirubin encephalopathy

bilirubin from albumin binding sitespotentially causingbilirubin encephalopathy

particularly those who are premature because ceftriaxone is reported to displace bilirubin from albumin binding sitespotentially causingbilirubin encephalopathy

It should not be used in hyperbilirubinemic neonates , particularly those who are premature because ceftriaxone is reported to displace bilirubin from albumin binding sitespotentially causingbilirubin encephalopathy

albumin binding sitespotentially causingbilirubin encephalopathy

m albumin binding sitespotentially causingbilirubin encephalopathy

to be broken downleadingto higher levels of bilirubin to be conjugated

previous severe penicillin allergiesshould not be used in hyperbilirubinemic neonates , particularly those who are premature because ceftriaxone is reported to displace bilirubin from albumin binding sitespotentially causingbilirubin encephalopathy

Phototherapycausesphotodegradation of bilirubin

the usual amount of red blood cells to be broken downleadingto higher levels of bilirubin to be conjugated

the outflow of bileresultin the reabsorption of conjugated bilirubin

hepatic or hemolytic illness energy department(passive) caused bybilirubin in csf

Excessive bruising from a traumatic birth causes more than the usual amount of red blood cells to be broken downleadingto higher levels of bilirubin to be conjugated

Hyperbilirubinemiamay causebilirubin to accumulate in

nonvascular plant or hemolytic malady eutherian(passive) caused bybilirubin in csf

any drugcausingBILIRUBIN CONJUGATED

DrugscausedBilirubin Conjugated

p. Aeruginosa(passive) is caused byConjugated bilirubin

the yellow color of the skin and whites of the eyes(passive) caused bythe yellow color of the skin and whites of the eyes

in a yellowish pigmentation of the skinresultsin a yellowish pigmentation of the skin

to the back up of bilirubin in the bloodleadsto the back up of bilirubin in the blood

jaundicecausesjaundice

to brain damagemay leadto brain damage

to the backleadsto the back

these serious neurological problemscausesthese serious neurological problems

severe hearing disordersmay also causesevere hearing disorders

increased degradation of riboflavincan causeincreased degradation of riboflavin

some degree of brain damage and result in developmental problemsmay causesome degree of brain damage and result in developmental problems

due to obstruction biliary passagecauseddue to obstruction biliary passage

due to obstruction of biliary passagecauseddue to obstruction of biliary passage

in neonatal death or multisystem acute manifestations and long - term impairmentscan resultin neonatal death or multisystem acute manifestations and long - term impairments

in neonatal death or multisystem acute manifestationscan resultin neonatal death or multisystem acute manifestations

This jaundice(passive) however ... is caused byThis jaundice

hyperbilirubinemia(passive) can be caused byhyperbilirubinemia

to serious health problems , including a liver disease known as cholestasis , which involves impairment in the excretion of bilecan also leadto serious health problems , including a liver disease known as cholestasis , which involves impairment in the excretion of bile

jaundice builds up to dangerous levelscausesjaundice builds up to dangerous levels

in death or irreversible brain damage in survivor ( 1 - 3can resultin death or irreversible brain damage in survivor ( 1 - 3

to increased total bilirubinshould leadto increased total bilirubin

jaundice(passive) caused byjaundice

neurological complications(passive) caused byneurological complications

to greater plasmacontributedto greater plasma

to jaundiceleadingto jaundice

to cerebral palsyleadingto cerebral palsy

permanent brain damagecausespermanent brain damage

to irreversible kernicterusleadsto irreversible kernicterus

to kernicterusleadingto kernicterus

in permanent neurological damagecan resultin permanent neurological damage

in permanent neurological damagecan resultin permanent neurological damage

to hearing lossleadingto hearing loss

brain damage or deathcausingbrain damage or death

1causes1

to severe jaundice in first few days of lifeleadingto severe jaundice in first few days of life

initiallycausesinitially

to STBcontributedto STB

to kernicteruscan leadto kernicterus

in kernicteruscan resultin kernicterus

jaundicecausesjaundice

their increasecausingtheir increase

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