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Smart Reasoning:

C&E

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Qaagi - Book of Why

Causes

Effects

a genetic mutationcausesa problem in the complement system

a rare diseasecausesexcessive activation of the complement system

Atypical Haemolytic Uraemic Syndrome , or ... a rare diseasecausesexcessive activation of the complement system

by blood loss , low dietary levels of iron , or a disease condition that inhibits iron uptake(passive) usually caused by deficiency of iron in the system

by mutations in the C2 gene(passive) is caused byComplement component 2 deficiency

At least five mutations in the C2 gene have been foundto causecomplement component 2 deficiency

an inherited gene mutationcausesan abnormality of the immune complement system

process issuescontributeto system deficiency

Some human errorcontributedto a system deficiency

the molecular mechanismcausingthe dysregulation of the complement system

mutationscausecomplement deficiency disorders

by any one of several different alterations in the structure of complement component 2(passive) caused bya type of complement deficiency

by any one of several different alterations in the structure of complement(passive) caused bya type of complement deficiency

inside 90 % of the population(passive) is discoveredSupplement N deficiency

regionalism ... which is goingto contributecomplement the system

HAE is a genetic disorder involving lack of functional C1 esteraseleadingto overactivity of the complement system

the presence of this variant in the homozygous state in P3 and P4 ... enoughto causeLIG1 deficiency

fibromyalgia symptomsmay resultfrom a deficiency in the endocannabinoid system

Fibromyalgia could be one of thesesyndromes resultingfrom a deficiency in the Endocannabinoid system

MutationscausingVLDLR deficiency

by mutations in the FH gene(passive) is caused byFumarase deficiency

in which either codon 54 or 57 of the mannose - binding protein gene is alteredcausingdeficient complement activation

by any one of several different alterations in the structure of complement component 2(passive) caused bycomplement deficiency

Autoantibodies ... have also been describedmay causefurther complement deficiency

by any one of several different alterations in the structure of complement(passive) caused bycomplement deficiency

Polymorphism in ficolin-3 gene ( FCN3can leadto complement deficiency

by any one of several different alterations in the structure of complement component 2 ... Complement - Biology and Medicine(passive) caused bycomplement deficiency

by very poor family genes and nutrition(passive) caused bysupplement deficiencies

changes ( mutations ) in the ACADVL gene(passive) is caused byVLCAD deficiency

bad nourishment and genes(passive) caused bysupplement deficiencies

a gene change , or mutation(passive) is caused byVLCAD Deficiency

any drugcausingLIPOPROTEIN DEFICIENCY

metabolic diseasecausingneurodevelopmental deficiency

A form of Batten diseasecausesTPP1 deficiency

diet ... likelyto causemicronutrient deficiency

by mutation or downregulation of dysferlin(passive) caused bydysferlin deficiency

a reduction of the HK activitycauseshexokinase deficiency

the HK activitycauseshexokinase deficiency

Immune system abnormalities(passive) may be caused partly byImmune system abnormalities

to immunocompromise and overwhelming infection and sepsiscan leadto immunocompromise and overwhelming infection and sepsis

muscle weakness , poor reflexes and retinal problemscausesmuscle weakness , poor reflexes and retinal problems

in opsonization , chemotaxis and bacterial lysiscausingin opsonization , chemotaxis and bacterial lysis

alterations in opsonization , chemotaxis and bacterial lysiscausingalterations in opsonization , chemotaxis and bacterial lysis

the nervous system and contributes to weaknessinfluencesthe nervous system and contributes to weakness

all target diseases(passive) caused byall target diseases

to some very serious diseasescan leadto some very serious diseases

recurrent Causes Causes of Disorders of complement systemcausingrecurrent Causes Causes of Disorders of complement system

diseases(passive) caused bydiseases

recurrent infections ... Introduction Causes ( 1 conditionscausingrecurrent infections ... Introduction Causes ( 1 conditions

to an immune disorderare contributingto an immune disorder

in local inflammation , autoimmune reactions , and tissue damagemay resultin local inflammation , autoimmune reactions , and tissue damage

the kidney(passive) caused bythe kidney

the one(passive) caused bythe one

muscle weakness and paincan ... causemuscle weakness and pain

muscle weakness and paincan ... resultmuscle weakness and pain

in heart diseasecan resultin heart disease

in the breakcan resultin the break

to neurological difficulties and pernicious anemiacan leadto neurological difficulties and pernicious anemia

Primary aHUS(passive) is caused byPrimary aHUS

rickets and with the elderly it results in osteoporosiswill causerickets and with the elderly it results in osteoporosis

muscle pain and weaknesscan ... resultmuscle pain and weakness

the atypical HUS(passive) caused bythe atypical HUS

to serious complicationscan leadto serious complications

Atypical hemolytic uremic syndrome ( aHUS(passive) is caused byAtypical hemolytic uremic syndrome ( aHUS

to suffering as well as other uncomfortable indicatorscan leadto suffering as well as other uncomfortable indicators

< p > Atypical hemolytic uremic syndrome ( aHUS(passive) is caused by< p > Atypical hemolytic uremic syndrome ( aHUS

diseases(passive) caused bydiseases

to accelerated amyloidleadsto accelerated amyloid

Fibromyalgia(passive) may be caused byFibromyalgia

to believe(passive) are causedto believe

to feel(passive) are caused byto feel

development of other immune functionsmay influencedevelopment of other immune functions

to accelerated amyloid plaque deposition and neurodegeneration and modulation of the microglia / macrophage phenotype in amyloid precursor protein transgenic miceleadsto accelerated amyloid plaque deposition and neurodegeneration and modulation of the microglia / macrophage phenotype in amyloid precursor protein transgenic mice

in the formation of various chemotactic agentsresultsin the formation of various chemotactic agents

to a decrease in the formation of antibody - antigen - complement immune complexesleadsto a decrease in the formation of antibody - antigen - complement immune complexes

to susceptibility to infectionleadsto susceptibility to infection

to susceptibilityleadsto susceptibility

Deficiency of regulatory proteins results in excessive complement activation that causes Complement activation pathways(passive) is composedDeficiency of regulatory proteins results in excessive complement activation that causes Complement activation pathways

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Smart Reasoning:

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