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Qaagi - Book of Why

Causes

Effects

foundis composedof 2 circular chromosomes

genomescomposedof several circular chromosomes

first(passive) were ... discoveredRing chromosomes

hybridization ( FISH ) techniques ... the detection of individual translocations involving different chromosomesto paintindividual chromosomes

from Normal Drosophila X - chromosomes's unusual frequencies of recombination(passive) were discoveredRing chromosomes

by the same - sex parents(passive) contributed bywhole chromosomes

ableto designentire chromosomes

aneuploidy(passive) caused byextra chromosomes

Mutations in the essential spindle checkpoint gene bub1causechromosome missegregation

to seewould ... resultin a circular chromosome

mutations in bub1causechromosome missegregation

caused abnormal mitotic spindle formation and/or spindle function due to substrate stiffnessconsequently causingchromosome missegregation

by cohesion deficiencies(passive) caused byaberrant chromosomes

inhibition of RNAPII activity in mitotic cells ... sufficientto causechromosome missegregation

condensin deficiency(passive) caused bychromosome missegregation

of chromatin Chromatin = DNA + proteins(passive) are composed Eukaryotic chromosomes

The complex of DNA and proteins , mainly histonescomposeeukaryotic chromosomes

of DNA and histone proteins(passive) are composedEukaryotic chromosomes

two breaks in the chromosome(passive) caused bychromosome

by locus duplications and deletions(passive) caused byhomoeologous chromosomes

A dominant negative formcausedmissegregation of chromosomes

by radiation(passive) are caused bydicentric chromosomes

by radiation(passive) are causeddicentric chromosomes

which proposedcausedchromosome

by damaged(passive) caused bychromosome

of five exons(passive) is composedchromosome

chromatin(passive) are composedheterochromatic chromosomes

of a single DNA molecule and many proteins(passive) are composedChromosomes

ETOPOSIDEcausingCHROMOSOME

by mutations Some caused by an change in chromosome number(passive) are caused bychromosomes

of what Genes are small sections of DNA within the genome that code for proteins(passive) are composedChromosomes

Landpaintedchromosome

in a different color(passive) is paintedchromosome

of DNA and many proteins(passive) are composedChromosomes

that acetaldehyde can break and damage DNA within blood stem cellscausingrearranged chromosomes

RNAicausespolytene chromosomes

of genes which are composed of DNA(passive) are composedChromosomes

of DNA and protein(passive) are composed primarilyChromosomes

of DNA and protein(passive) are composedChromosomes

Y chromosometo resultchromosomes

of DNAcomposedof DNA

of double stranded DNAcomposedof double stranded DNA

a baby`s sex and sexinfluencea baby`s sex and sex

of double - stranded DNAcomposedof double - stranded DNA

a baby`s sex and regardless of whetherinfluencea baby`s sex and regardless of whether

Prokaryotic genomes(passive) are composedProkaryotic genomes

found(passive) is composedfound

in dimeric or catenated chromosomescan resultin dimeric or catenated chromosomes

from breaks at the ends of both chromosome arms with subsequent fusion of the broken endsresultfrom breaks at the ends of both chromosome arms with subsequent fusion of the broken ends

in turn to further genomic instabilityleadingin turn to further genomic instability

to a chromosomal disordercan leadto a chromosomal disorder

in cells containing fragmented nucleiresultingin cells containing fragmented nuclei

of four regionscomposedof four regions

of double stranded DNAcomposedof double stranded DNA

of about 4 . 6 millioncomposedof about 4 . 6 million

to cloning humansWill ... leadto cloning humans

to chromosome hypercondensationleadingto chromosome hypercondensation

Metaphase , or(passive) are composedMetaphase , or

from telomere dysfunctionresultingfrom telomere dysfunction

from intrachromosomal recombinationresultingfrom intrachromosomal recombination

in increased expression of growth promoting genes14resultingin increased expression of growth promoting genes14

from chromosome breaks or telomere - to - telomereoriginatingfrom chromosome breaks or telomere - to - telomere

in Turner syndromecan resultin Turner syndrome

from the abnormal fusion of two chromosome pieces , each of which includes a centromereresultfrom the abnormal fusion of two chromosome pieces , each of which includes a centromere

to birth defectsmay leadto birth defects

in UPDresultingin UPD

Genetic mutations(passive) caused byGenetic mutations

from MPS1 inhibitionresultingfrom MPS1 inhibition

from the replication of the chromosomes and the synapsis of homologs without cell divisionresultingfrom the replication of the chromosomes and the synapsis of homologs without cell division

of genesare composedof genes

to leukaemogenesiscontributeto leukaemogenesis

a wealth of knowledge regarding chromosome regulationhave contributeda wealth of knowledge regarding chromosome regulation

from core chromosomes and subsequently degenerated and evolved separatelymay have originatedfrom core chromosomes and subsequently degenerated and evolved separately

from inevitable collisions in an areacan resultfrom inevitable collisions in an area

in uniparental disomy ( UPDresultingin uniparental disomy ( UPD

from subsequent cycles of DNA replication that are not followed by nuclear divisionresultfrom subsequent cycles of DNA replication that are not followed by nuclear division

of thick rods made up of tightly but irregularly folded fibers that can subsequently coil to form thicker condensed chromatidsare composedof thick rods made up of tightly but irregularly folded fibers that can subsequently coil to form thicker condensed chromatids

up throughout twenty three twosis setup throughout twenty three twos

in transloca- tions.53 , 1975resultingin transloca- tions.53 , 1975

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