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to block the substances ( proteins ) that lead to that growth , which include vascular endothelial growth factor ( VEGF ) and placental growth factor(passive) are designedAngiogenesis inhibitors
from a variety of sources(passive) have been discoveredAngiogenesis inhibitors
to stop tumours growing by cutting off their blood supply(passive) are designedAngiogenesis inhibitors
Up till now , many efforts have madeto discovernecroptosis inhibitors
by Denali(passive) contributed byRIPK1 Inhibitors
Denali(passive) contributed byRIPK1 Inhibitors
Administration ofresultsVEGF inhibitors
to be complementary to a miRNA(passive) were ... designedoligonucleotide inhibitors
to limit the effects of a cell structure called a proteasome(passive) are designedProteasome inhibitors
from natural sources , including : tree bark , fungi , shark muscle and cartilage , sea coral , green tea and herbs(passive) have been discoveredAngiogenesis inhibitors
to protect the cholinergic system , which is essential for memory and learning and is progressively destroyed in AD(passive) are designedCholinesterase inhibitors
Concomitant use withmay resultcholinesterase inhibitors
to regulate glucose by manipulating a protein found in the renal system(passive) are designedSGLT2 inhibitors
Prior tasks at AstraZeneca searching for selective EGFR6?hER27 orresulted6d?7d inhibitors
to control diabetes by blocking reabsorption(passive) are designedSGLT2 inhibitors
to increase the level of acetylcholine in the brain(passive) are designedCholinesterase Inhibitors
a rational structure - based virtual screening approach(passive) mostly discovered byinhibitors
a targeted programto discoverPARG inhibitors
to keep the protein from performing its function(passive) are designedSGLT2 inhibitors
on the basis of structure - based pharmacophore model and molecular docking(passive) were designedinhibitors
by pharmacophore - based virtual screening , molecular docking and bioassay(passive) designed byinhibitors
by the rational drug design approaches in(passive) discovered byinhibitors
via high throughput screening ( HTS ) of chemical libraries(passive) were discoveredinhibitors
High - throughput screening effortsto discoverinhibitors
by the rational drug design approaches in the recent 5-year(passive) discovered byinhibitors
the rational drug design approaches in the recent 5-year(passive) discovered byinhibitors
by structure - based methods(passive) discovered byinhibitors
screening compound libraries(passive) discovered byinhibitors
A variety of natural and synthetic inhibitors of ATP synthase(passive) have been discoveredInhibitors
screening effortsto discoverinhibitors
cancer medicationsare ... designedinhibitors
to control diabetes by blocking reabsorption of glucose by the kidneys , impacting normal kidney function and allowing more sugar to be passed from the body through urine(passive) are designedSGLT2 inhibitors
by using the binding pocket(passive) designed byinhibitors
by virtual screening(passive) discovered byinhibitors
using computational tools(passive) were designedInhibitors
Even that doesn t work , selective serotonin reuptakecauseinhibitors
in a large screening effort(passive) were discoveredinhibitors
without an initial understanding of how they work(passive) often are discoveredInhibitors
medicinal chemistry(passive) have been discovered byinhibitors
Strategy ... : structure of a complex of proteinaseto designinhibitors
url =causesurl =
PtdIns4P accumulation in the ERcausePtdIns4P accumulation in the ER
to target conserved regions of various targetsdesignedto target conserved regions of various targets
apoptosiscausedapoptosis
to target conserved regions of various HCVdesignedto target conserved regions of various HCV
in reduced toxicityresultedin reduced toxicity
to hyperphosphorylation of AKTcan leadto hyperphosphorylation of AKT
to its hyperphosphorylationcould leadto its hyperphosphorylation
to its hyperphosphorylationcan leadto its hyperphosphorylation
to its hyperphosphorylationmight leadto its hyperphosphorylation
profound intraoperative hypotensioncan causeprofound intraoperative hypotension
to inhibit leukemia cell proliferationresultingto inhibit leukemia cell proliferation
in collagen accumulationresultingin collagen accumulation
to reduce cell growth signaling that is overactive in cancerare designedto reduce cell growth signaling that is overactive in cancer
gastrointestinal side effects(passive) caused bygastrointestinal side effects
side effectscan causeside effects
MHAcausingMHA
to clinical improvementmay leadto clinical improvement
bradycardiacausebradycardia
to changes in blood lipid concentrationsleadto changes in blood lipid concentrations
in reduced cholinesterase inhibitor efficacymay resultin reduced cholinesterase inhibitor efficacy
parasympathetic activityinfluenceparasympathetic activity
nervous system over - stimulationcausenervous system over - stimulation
Dementia From Brain ConditionscausesDementia From Brain Conditions
The muscular paralysis of excess acetylcholine(passive) was caused byThe muscular paralysis of excess acetylcholine
in overstimulation of the nervous systemresultin overstimulation of the nervous system
to weight lossmay leadto weight loss
to weight lossDo ... leadto weight loss
to weight losscontributeto weight loss
in reduced cholinesterasemay resultin reduced cholinesterase
insomniamay causeinsomnia
harmmay causeharm
The prevalence of acute gastroduodenal injury(passive) caused byThe prevalence of acute gastroduodenal injury
probablyleadprobably
the autonomic nervous system(passive) caused bythe autonomic nervous system
an increase in fentanyl plasma concentrations , which could increase or prolong the two the therapeutic and adverse effectsmay causean increase in fentanyl plasma concentrations , which could increase or prolong the two the therapeutic and adverse effects
in continual Pax3 expression and proliferation of satellite cells ( 36resultin continual Pax3 expression and proliferation of satellite cells ( 36
in severe hypotension and deterioration in renal function , including renal failuremay resultin severe hypotension and deterioration in renal function , including renal failure
parasympathetic activity more potently than other clinical conditions studied previouslyinfluenceparasympathetic activity more potently than other clinical conditions studied previously
growth arrest , differentiation , and apoptosis of many tumor types in vitro and in vivocausegrowth arrest , differentiation , and apoptosis of many tumor types in vitro and in vivo