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to induce reorganization of cellular membrane constituentsleadingto a lipid bilayer marked by increased membrane concentrations of cholesterol
phospholipid synthesisleadingto increased membrane cholesterol : phospholipid ratio
phospholipids synthesisresultingin an increased ' membrane cholesterol : phospholipid ratio
circulating cholesteroldoes ... contributeto muscle membrane cholesterol content
increased expression of ABCA1can causea general increase in membrane cholesterol
de novo cholesterol synthesiscontributessignificantly to the regulation of membrane cholesterol
an intracellular signalleadingto translocation of cholesterol from intracellular sites to the plasma membrane
acute CFTR inhibition ... that both mild and severe CFTR mutationsresultin elevated membrane cholesterol content
a potential mechanismleadingto increased cholesterol accessibility at the plasma membrane
of a highly hydrophobic sterol ring system and a small 3-hydroxyl moiety(passive) is composedCholesterol , a major constituent of membrane rafts
Cholesterol supplementation in the culture mediumresultedin increased cell membrane cholesterol content
phospholipids synthesisresultingin an increased ' membrane cholesterol
phospholipid synthesis ... phospholipid ratioleadingto increased membrane cholesterol
These data suggestedcauseddepletion of intracellular membrane cholesterol
As well , they foundcauseda decrease in membrane fluidity and cholesterol levels
expression of the geneledto increased plasma membrane cholesterol
free radicalscausedlipid peroxidation led to membrane fluidity
the incorporation of DHA or EPA into membrane phospholipids(passive) caused bymembrane free cholesterol
The mechanism by whichinfluencesmovement of cholesterol to the plasma membrane
The lack of free cholesterolleadsto cholesterol depletion of the membrane
ACAT inhibitionresultedin increased plasma membrane cholesterol levels
specific cellular eventscan leadto increases in membrane cholesterol
by M?C. ( I(passive) caused bymembrane cholesterol depletion
oxidationcausesmembrane lipid peroxidation and decreases membrane fluidity
specific cellular eventscan leadto increases in membrane cholesterol levels
the direct administration of the water - soluble cholesterolleadsto the increases in the membrane cholesterol levels
De novo cholesterol synthesiscontributesto membrane cholesterol accessibility
inhibitorscausecholesterol depletion from the plasma membrane
by IR(passive) caused bymembrane phospholipid and cholesterol
by free radicals(passive) caused bymembrane lipid peroxidation
Also , hydroxyl radicals reactto causemembrane lipid peroxidation
by oxidative stress(passive) caused bymembrane lipid peroxidation
Reactive oxygen species can also oxidize cholesterol and unsaturated fatty acidscausingmembrane lipid peroxidation
The excessive production of free radicalscausesmembrane lipid peroxidation
oxidationcausesmembrane lipid peroxidation
vesiclescomposedof a lipid bilayer membrane
by cold stress(passive) caused bymembrane lipid peroxidation
a vesiclecomposedof a lipid bilayer membrane
spherical vesiclescomposedof lipid bilayers membrane
LPSmay influencemembrane cholesterol
in an increased distribution of aqueous phase within the liposomal vesiclesresultsin an increased distribution of aqueous phase within the liposomal vesicles
a mechanism(passive) influenced bya mechanism
in changes in vascular functioncan resultin changes in vascular function
this conditioncan causethis condition
a parameter(passive) influenced bya parameter
Breast cancer(passive) is influenced byBreast cancer
alsoledalso
in breakdown of the membrane structure andresultingin breakdown of the membrane structure and
ligand - independent activation of Fas and apoptosiscausesligand - independent activation of Fas and apoptosis
in a decrease of Wnt3 association with cholesterol - dependent domains in live zebrafishalso resultsin a decrease of Wnt3 association with cholesterol - dependent domains in live zebrafish
to a moderate increase in the full - length APP levels ( Figure 2(aledto a moderate increase in the full - length APP levels ( Figure 2(a
to cholesterol depletion in the ER ... activation of transcription of cholesterogenic genes ... causing accumulation of intracellular cholesterol ( 43ledto cholesterol depletion in the ER ... activation of transcription of cholesterogenic genes ... causing accumulation of intracellular cholesterol ( 43
the clustering of GPI - anchored proteins to break upcausesthe clustering of GPI - anchored proteins to break up
alsocausesalso
in rounding of the MSCs and disorganization of the actin networksresultedin rounding of the MSCs and disorganization of the actin networks
neurodegeneration and could point to a role for cholesterol in other neurodegenerative diseasescauseneurodegeneration and could point to a role for cholesterol in other neurodegenerative diseases
of phospholipidscomposedof phospholipids
significantlyinfluencessignificantly
its destructioncausingits destruction
endosomes in hippocampal neuronal cells to enlarge by 31%.10causedendosomes in hippocampal neuronal cells to enlarge by 31%.10
almost complete elimination of the organization in reversible fashion ... allowing the researchers to single out Cholesterol as the main molecular organizer of the protein assembliescausedalmost complete elimination of the organization in reversible fashion ... allowing the researchers to single out Cholesterol as the main molecular organizer of the protein assemblies
of phospholipids containing 18-carbon acyl chainscomposed mainlyof phospholipids containing 18-carbon acyl chains
mainly of phospholipids containing 18-carbon acylcomposedmainly of phospholipids containing 18-carbon acyl
mainly of phospholipids containing 18-carbon acyl chainscomposedmainly of phospholipids containing 18-carbon acyl chains
in permeabilization of cellsresultingin permeabilization of cells
significantlyinfluencedsignificantly
to the organization ofcontributesto the organization of
this phase behaviourcan influencethis phase behaviour
this phase behaviour [ 2can influencethis phase behaviour [ 2
stronglyinfluencesstrongly
to such an enantioselective interactioncontributesto such an enantioselective interaction
endosomes in hippocampal neuronal cells to enlarge by 31%.10 ( Endosomes are organelles in which molecules are sorted on their way to lysosomes for degradationcausedendosomes in hippocampal neuronal cells to enlarge by 31%.10 ( Endosomes are organelles in which molecules are sorted on their way to lysosomes for degradation
inflammationcan causeinflammation
to disruption in the cell membrane organizationleadingto disruption in the cell membrane organization
the accessibility of the D4 probescould influencethe accessibility of the D4 probes
to cell membrane flexibility and is a precursor of steroid hormonescontributesto cell membrane flexibility and is a precursor of steroid hormones
about 30 % of all animal cell membranescomposesabout 30 % of all animal cell membranes
the generation of Ainfluencethe generation of A
this interaction ... as examined in several experimental models including cultured cells , virus - like - particles and liver cell plasma membranesinfluencesthis interaction ... as examined in several experimental models including cultured cells , virus - like - particles and liver cell plasma membranes
certain ABC transporters and the ComB DNA transporter in H. pylori ( Hildebrandt , Trainor and McGee , unpublished resultsmay ... influencecertain ABC transporters and the ComB DNA transporter in H. pylori ( Hildebrandt , Trainor and McGee , unpublished results