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Qaagi - Book of Why

Causes

Effects

LPSmay influencemembrane cholesterol

The lipid raft disorganizationresultingfrom lowering neuronal membrane cholesterol

the lipid environment surrounding cholesterolinfluencesmembrane cholesterol binding by CDCs

an increase in the degree of unsaturationleadsto an increase membrane fluidity amount of cholesterol present affect on membrane fluidity cholesterol

The accumulation of lysosomal free cholesterolcan directly causean increase in lysosomal membrane cholesterol content.38

MβC. ( I(passive) caused bymembrane cholesterol depletion

acquires detergent - like propertiesleadingto lysosomal membrane permeabilization Cholesterol

the role of caveolaeare composedof membrane cholesterol

thus requiring a greater amount of energy ( and therefore heatto causecholesterol to move around the membrane

if MβCD treated cultures were incubated with 0.05 mM of water soluble cholesterol ( WSC ) diluted in serum free mediacausingmembrane cholesterol to be replenished

toward electrical maturation of hearingcontributestoward electrical maturation of hearing

to the organization of these domainscontributesto the organization of these domains

a progressive decrease in red cell deformability ... as measured by filtration [ 33causeda progressive decrease in red cell deformability ... as measured by filtration [ 33

to an increase in membrane fluidity [ 5leadingto an increase in membrane fluidity [ 5

this phase behaviour [ 2can influencethis phase behaviour [ 2

certain ABC transporters and the ComB DNA transporter in H. pylori ( Hildebrandt , Trainor and McGee , unpublished resultsmay ... influencecertain ABC transporters and the ComB DNA transporter in H. pylori ( Hildebrandt , Trainor and McGee , unpublished results

to such an enantioselective interactioncontributesto such an enantioselective interaction

in an increased distribution of aqueous phase within the liposomal vesicle thereby reducing the encapsulation of the hydrophobic nevirapine [ 46resultsin an increased distribution of aqueous phase within the liposomal vesicle thereby reducing the encapsulation of the hydrophobic nevirapine [ 46

solidification of phospholipids during low tempspreventssolidification of phospholipids during low temps

atherosclerotic plaque formation and leads to an increased risk for coronary artery diseasecausesatherosclerotic plaque formation and leads to an increased risk for coronary artery disease

leakage of water and ions from the cellpreventsleakage of water and ions from the cell

movement of the fatty acyl chains of phospholipids in the membrane ... a process that is called fluiditypreventsmovement of the fatty acyl chains of phospholipids in the membrane ... a process that is called fluidity

its surface free energyinfluencesits surface free energy

ethanol 's modulation of BK in a complex manner ... including an interaction with the channel proteininfluencesethanol 's modulation of BK in a complex manner ... including an interaction with the channel protein

substantially to the distribution and regulation of both AC8 and AC8M1contributessubstantially to the distribution and regulation of both AC8 and AC8M1

to ATPSβ translocation from mitochondria to membrane rafts , together withleadingto ATPSβ translocation from mitochondria to membrane rafts , together with

lipid rafts(passive) provoked bylipid rafts

conformation of MHC - II proteinmay influenceconformation of MHC - II protein

the PMNL sensitivity to shear stressinfluencesthe PMNL sensitivity to shear stress

lysosomal membrane stabilization , inflammasome activation , and downstream inflammationcan influencelysosomal membrane stabilization , inflammasome activation , and downstream inflammation

to an increased Vmax while Km remains unchangedleadsto an increased Vmax while Km remains unchanged

its subcellular distribution(passive) was influenced byits subcellular distribution

to CagA features and pathogenesis January 14 ... 2016January 15 , 2016contributesto CagA features and pathogenesis January 14 ... 2016January 15 , 2016

nanoscale electrostatic domains which induce preferential binding of amyloid peptide ... while membrane melatonin reduces amyloid - membrane interactions , protecting the membrane from amyloid attackcreatesnanoscale electrostatic domains which induce preferential binding of amyloid peptide ... while membrane melatonin reduces amyloid - membrane interactions , protecting the membrane from amyloid attack

in the augmentation in both cGMP and VASP phosphorylation to a level similar to those observed in NHFresultedin the augmentation in both cGMP and VASP phosphorylation to a level similar to those observed in NHF

to CagA functions and pathogenesiscontributesto CagA functions and pathogenesis

pores and lyse target cellsto createpores and lyse target cells

cholesterol to be directed towards the ER for esterification by ACAT rather than being released by the appropriate external acceptor , i.e. HDLcausingcholesterol to be directed towards the ER for esterification by ACAT rather than being released by the appropriate external acceptor , i.e. HDL

to Lv2 restrictionleadsto Lv2 restriction

to the organization of tetraspanin microdomains on the surface of live cellscontributesto the organization of tetraspanin microdomains on the surface of live cells

to induction of inflammation in Hp - infected AGS cellsleadingto induction of inflammation in Hp - infected AGS cells

to CagA features and pathogenesis | GSK3 inhibitorcontributesto CagA features and pathogenesis | GSK3 inhibitor

to higher β cleavage results in higher Aβ productionleadingto higher β cleavage results in higher Aβ production

it from hardeningpreventingit from hardening

in clustering of dyneins into microdomainsresultsin clustering of dyneins into microdomains

transport activity and inhibitor binding in neurotransmitter transporters(passive) are ... influenced bytransport activity and inhibitor binding in neurotransmitter transporters

recruitment of PrPc to the cell membrane and whether the generation of 17 kDa tau is dependent on the Aβ - PrPc interactioninfluencesrecruitment of PrPc to the cell membrane and whether the generation of 17 kDa tau is dependent on the Aβ - PrPc interaction

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