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Qaagi - Book of Why

Causes

Effects

their abilityto influencecholesterol crystal growth

small crystals of cholesterol dispersed from atherosclerotic plaques of the aorta(passive) is caused byCholesterol crystal embolism ( CCE

a systemic diseaseresultingfrom cholesterol crystal embolization

aortic plaquescausingembolization of cholesterol crystals

biliary proteinsinfluencenucleation of cholesterol crystals

Gallstones Gallstones are formed when bile becomes saturated with cholesterol - they are , in factcomposedof cholesterol crystals

Cholesterol gallstonescomposed predominantlyof cholesterol crystals

a poor diet , stress , obesity , a sedentary lifestyle , smoking , and age(passive) is caused byElevated cholesterol

small arteriescausedon cholesterol crystals

that atherosclerosis may be treatedinfluencingon cholesterol crystals

genetic conditionscausingelevated cholesterol

Elevated cortisolcauseselevated cholesterol

In addition ,can causeelevated cholesterol

the contentscomposed mostlyof cholesterol crystals

Hypothyroidismcan causeelevated cholesterol

poor digestion of fats , low essential fatty acids , and/or high LDL(passive) may be caused byCholesterol crystals

The LDL type particlecausescholesterol plaques

disorderscauseelevated cholesterol

varieties of gallstonesmost composedof cholesterol crystals

Microembolicomposedof cholesterol crystals

constipationcan causeelevated cholesterol

cortisonecan causeelevated cholesterol,

Overweight ... ableto causecholesterol plaques

Undiagnosed and undertreated hypothyroidismcan causeelevated cholesterol

Liu J. Microembolicomposedof cholesterol crystals

Another thingcan causeCholesterol Dysregulation

their abilityto causecholesterol nucleation

Liver and Bladder problems brought on by all the abovecan causeCholesterol Dysregulation

The release of cholesterol due to a plaque rupturecan causecholesterol embolisms

biliary proteins and lipid peroxidationinfluencecholesterol nucleation

ABCA1may influencecholesterol efflux

high TSH levels alonecan influencecholesterol levels3

mutations in the NPC1 genecausingunesterified cholesterol

the NPC1 genecausingunesterified cholesterol

The consumption of too much saturated fat , trans fat , andcan causecholesterol

A diet which contains foods that are rich in fat andcan contributecholesterol

An Unhealthy Diet A diet that includes great amounts of saturated fat , trans fat , andwill leadcholesterol

by increased cholesterol consumption and(passive) caused bycholesterol

by increased cholesterol consumption and abnormal lipoprotein structure(passive) caused bycholesterol

Diet And Cholesterol can resultCholesterol

to formation of gallstonesresultsto formation of gallstones

This yellow discoloration(passive) is mainly caused byThis yellow discoloration

to the occlusion of small arteries in a variety of organsleadingto the occlusion of small arteries in a variety of organs

in partial or total occlusion of multiple small arteries within the kidneyresultingin partial or total occlusion of multiple small arteries within the kidney

the small intestine(passive) caused bythe small intestine

the small intestine(passive) caused bythe small intestine

Ileus(passive) caused byIleus

Ileus(passive) caused byIleus

to blockage and stroke or cardiovascular diseasecan leadto blockage and stroke or cardiovascular disease

to atherosclerosiscontributeto atherosclerosis

atherosclerosis ((passive) caused byatherosclerosis (

to plaque rupturemay contributeto plaque rupture

plaque rupturecauseplaque rupture

to atherosclerosis , or " hardening of the arteriescontributeto atherosclerosis , or " hardening of the arteries

to plaquemay contributeto plaque

to gallstone formationleadto gallstone formation

Most gallstones(passive) are composedMost gallstones

inflammation through the activation of the NLRP3 inflammasomecauseinflammation through the activation of the NLRP3 inflammasome

This inflammatory response(passive) caused byThis inflammatory response

the lipid core ( 4(passive) is ... composedthe lipid core ( 4

a giant cell reactioncausinga giant cell reaction

endothelial damage that can induce ischemiamay ... causeendothelial damage that can induce ischemia

from a proxoriginatingfrom a prox

to caspase-1 ( 17leadingto caspase-1 ( 17

an intracellular dose - dependent loss of 7,8-NPcausedan intracellular dose - dependent loss of 7,8-NP

mechanical damage to biological membranes : a proposed mechanism of plaque rupture and erosion leading to arterial thrombosiscausemechanical damage to biological membranes : a proposed mechanism of plaque rupture and erosion leading to arterial thrombosis

from a prox imal sourceoriginatingfrom a prox imal source

from a prox imal source e.goriginatingfrom a prox imal source e.g

from a prox imal source eoriginatingfrom a prox imal source e

from a prox imal source e.originatingfrom a prox imal source e.

physical damage to organelles by destabilization of the lysosomal compartment , rupture plasma membranescausephysical damage to organelles by destabilization of the lysosomal compartment , rupture plasma membranes

to small and large bowel infarctionleadingto small and large bowel infarction

to this life - threatening inflammation in the arteriescan contributeto this life - threatening inflammation in the arteries

to life - threatening inflammation in the arteriescan contributeto life - threatening inflammation in the arteries

to this life - threatening inflammationcan contributeto this life - threatening inflammation

massive immune responses and leads to life - threatening inflammation in arterial wallscausesmassive immune responses and leads to life - threatening inflammation in arterial walls

to a much higher risk of heart disease and strokes due to the formation of cholesterol deposits in the walls of blood vesselsleadsto a much higher risk of heart disease and strokes due to the formation of cholesterol deposits in the walls of blood vessels

atherosclerosis leading to the obstruction of blood vessels of the heart Lowering cholesterolcausesatherosclerosis leading to the obstruction of blood vessels of the heart Lowering cholesterol

atherosclerosis , a fatty buildup in the arteries which are called plaquecan causeatherosclerosis , a fatty buildup in the arteries which are called plaque

a heart attack due to the blockage of the arteries leading to the heartcan causea heart attack due to the blockage of the arteries leading to the heart

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