the resistance to antiestrogen therapyresultsfrom a cellular adaptation process
their interactionsleadto cellular function and adaptation
signalingleadingto chronic cellular adaptation
the Nrf2 pathway via redox signaling , ... , induction of protective proteins , and improvement of the mitochondrial redox stateleadingto chronic cellular adaptation
to cell survival or cell deathleadingto cell survival or cell death
alsocould ... leadalso
to the both type and functionleadsto the both type and function
to daily lifeleadsto daily life
to less frequent reviews and time spent to reach the goalleadingto less frequent reviews and time spent to reach the goal
to systemic changeleadto systemic change
to cancerwill leadto cancer
to cancercan leadto cancer
cancercausingcancer
to increased workloadleadsto increased workload
weight gaininfluenceweight gain
to most cancerscan leadto most cancers
to cancerscan leadto cancers
in cancerscan resultin cancers
in the uncontrolled development and division of cellsresultin the uncontrolled development and division of cells
to a decrease in apoptosiscould leadto a decrease in apoptosis
the uncontrolled expansion and division of cellscausethe uncontrolled expansion and division of cells
from frequent and reversible chromosomal amplificationsresultsfrom frequent and reversible chromosomal amplifications
to the uncontrolled advancement and division of cellsleadto the uncontrolled advancement and division of cells
in reduced drug uptakeresultin reduced drug uptake
to improvedleadto improved
to more general tissue - specific adaptations to hypoxialeadsto more general tissue - specific adaptations to hypoxia
to resistanceleadingto resistance
in reduced sensitivityresultsin reduced sensitivity
in long term behavioral dysfunctionmay resultin long term behavioral dysfunction
to drug resistanceleadingto drug resistance
to the progression of agingdirectly contributesto the progression of aging
to the development of a steroid - independent tumourleadingto the development of a steroid - independent tumour
to the aging of the whole organismcontributesto the aging of the whole organism
to ageing and the development and progression of diseasesleadsto ageing and the development and progression of diseases
to HIV-1 latencycontributeto HIV-1 latency
to HIV-1 latencycontributeto HIV-1 latency
to calorie restriction - induced preservation of skeletal musclecontributesto calorie restriction - induced preservation of skeletal muscle
to neurodegeneration leadsto neurodegeneration
to the regenerative capacity of plantscontributesto the regenerative capacity of plants
to a shift in the phenotype of the tumour cell from steroid dependence to steroid independence / growth factor dependenceleadingto a shift in the phenotype of the tumour cell from steroid dependence to steroid independence / growth factor dependence
to the relatively rapid restoration of aSox2-expressing cell populationleadsto the relatively rapid restoration of aSox2-expressing cell population
to neurodegeneration Sourceleadsto neurodegeneration Source