approximately 100 to 150 metabolic disorderscan causecarnitine deficiency
mutations in the SLC22A5 ( 5q31 ) gene encoding the sodium ion - dependent carnitine transporter ( OCTN2(passive) is caused byCarnitine deficiency
A large amountcan triggercarnitine deficiency
Carnitine deficiency or conditionscausingcarnitine deficiency
kidney disease and dialysis(passive) is caused bycarnitine deficiency
chronic valproate administration more so than acute(passive) to be caused byCarnitine deficiency
valproatescausingcarnitine deficiency
Tandem mass spectrometrydiscoveredcarnitine deficiency
downregulation of the carnitine acyltransferase genes(passive) caused bycarnitine deficiency
A medication used to treat seizures ... well knownto causecarnitine deficiency
The fate of supplemental carnitine ... knownto causecarnitine deficiency
the individual ... a risk allelemay causecarnitine deficiency
Recently , several drugs ( some of antibiotics , anticonvulsants , antineoplastics ) have been reportedto causecarnitine deficiency
short - term treatment of cefteram - pivoxil ( CFTM - PI ) which is one of pivaloyloxymethyl - esterified antibiotics in adult volunteers and diseased children(passive) caused bycarnitine deficiency
valproic acid ( VPAcausescarnitine deficiency
an abnormal accumulation of acidic wastes in the blood ( organic acidemiamay causean abnormal accumulation of acidic wastes in the blood ( organic acidemia
clinical myopathy or cardiomyopathycan causeclinical myopathy or cardiomyopathy
to decreased energy production and an increased risk of heart disease and anginaleadsto decreased energy production and an increased risk of heart disease and angina
cardiomyopathy , skeletal myopathy , hypoketotic coma , hypoglycemia , and hyperammonemiamay causecardiomyopathy , skeletal myopathy , hypoketotic coma , hypoglycemia , and hyperammonemia
muscle necrosis , myoglobinuria , lipid - storage myopathy , hypoglycemia , fatty liver , and Hyperammonemia with muscle aches , fatigue , confusion , and cardiomyopathymay causemuscle necrosis , myoglobinuria , lipid - storage myopathy , hypoglycemia , fatty liver , and Hyperammonemia with muscle aches , fatigue , confusion , and cardiomyopathy
liver failure , high ammonia , cerebral edema , cardiac arrhythmias , cardiomyopathy , and muscle weakness with rhabdomyolysisalso causesliver failure , high ammonia , cerebral edema , cardiac arrhythmias , cardiomyopathy , and muscle weakness with rhabdomyolysis
to muscle weakness , cardiomyopathy , hypoglycemia and liver dysfunction , conditions that are typical of mitochondrial diseases ( http://en.wikipedia.org/wiki/Mitochondrial_diseaseleadsto muscle weakness , cardiomyopathy , hypoglycemia and liver dysfunction , conditions that are typical of mitochondrial diseases ( http://en.wikipedia.org/wiki/Mitochondrial_disease
to accumulation of fatleadsto accumulation of fat
the body to be unable to use long - chain fatty acids as energycausesthe body to be unable to use long - chain fatty acids as energy
if any of those nutrients are at inadequate levelswill resultif any of those nutrients are at inadequate levels
many different problems , including heart failure , muscle weakness or muscle loss , anaemias and lack of energycausesmany different problems , including heart failure , muscle weakness or muscle loss , anaemias and lack of energy
non ketotic hypoglycemia dcan causenon ketotic hypoglycemia d
to cardiovascular disease ( CVDmay contributeto cardiovascular disease ( CVD
an impairment of other fatty acids oxidation leading to the obesity and lipids disorders that some VPA - treated patients experience [ 23could also causean impairment of other fatty acids oxidation leading to the obesity and lipids disorders that some VPA - treated patients experience [ 23
the metabolization of fats for energypreventsthe metabolization of fats for energy
the fatty acids to back up and accumulate in the blood ultimately resulting in additional deposition of fat , usually right in the areas where you already have the greatest accumulationcausesthe fatty acids to back up and accumulate in the blood ultimately resulting in additional deposition of fat , usually right in the areas where you already have the greatest accumulation
to heart and hepatic disease , myopathy , nonketotic hypoglycemia , and neurological complications.[1leadsto heart and hepatic disease , myopathy , nonketotic hypoglycemia , and neurological complications.[1
alsocan ... resultalso
after my daughter was bornwas discoveredafter my daughter was born
the paincausingthe pain
from developing in all dialysis patients by addition of L - carnitine hemodialysis and peritoneal dialysis solutions in low subtherapeutic concentrations that are equal to or below the concentration of free carnitine normal serumpreventedfrom developing in all dialysis patients by addition of L - carnitine hemodialysis and peritoneal dialysis solutions in low subtherapeutic concentrations that are equal to or below the concentration of free carnitine normal serum
in accumulation of non - oxidized fatty acyl - coenzyme A moleculesresultsin accumulation of non - oxidized fatty acyl - coenzyme A molecules