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Qaagi - Book of Why

Causes

Effects

Environmental factorsinfluencedlactation milk yield , lactation duration and dry period

Clinical interest in capillary blood lactate measurement ... these highly portable ( hand - held ) lactate instrumentsare designedfor rapid measurement of lactate concentration in capillary blood

metabolizing glucose / sugar(passive) caused bythe oxidative stress and lactate load

All ... Factorsinfluencingcapillary refill time

metabolizing Glucose ( carbs(passive) caused byoxidative stress and serum lactate

freecausesbreast milk to dry up load

inhibiting intake of pyruvate into the mitochondriaresultingin lactate secretion via lactate dehydrogenase ( LDH

an external treatmentmight causecells to accumulate lactate

One example of an external treatmentmight causecells to accumulate lactate

One example of an external treatmentmight causeplatelets to accumulate lactate

Both pathwaysultimately leadto the secretion of lactate

Consumption of alcohol metforminmay causebuildup of lactate

Consumption of alcoholmay causebuildup of lactate

Inhibition of PDH by PDK1 attenuates mitochondrial functionresultingin the shunting of pyruvate to lactate

other disorderscauseoverproduction of lactate

Pressurecan influencecapillary refill

oligodendrocytes appearto also influenceavailability of lactate

a condition or diseasehas causedlactate to accumulate

a disease or conditionis causinglactate to accumulate

the disease or condition a person hasis causinglactate to accumulate

the disease or condition a personhas is causinglactate to accumulate

structurally(passive) is ... composedLactate dehydrogenase

by oxygen deficiency to cells(passive) can be caused bylactate

by oxygen deficiency to cells(passive) can be causedlactate

diminished pyruvate flux through the citric acid cycle(passive) caused bylactate

hypoperfusion of any tissue(passive) may be caused byLactate

by gluconeogenesis(passive) caused bylactate

This increase ofcauseslactate

The increase incauseslactate

Any increase in effort or speed above this levelwill causelactate

within the method inside aerobic conditions(passive) has been hardly discoveredLactate

first(passive) was ... discoveredLactate

by damage to mitochondria(passive) caused bylactate

The drugcan causelactate

The build - up ofcauseslactate

concur-(passive) is caused byLactate

the intensive caresettinglactate

highly(passive) is ... influencedLactate

by syrosingopine(passive) caused bylactate

concur- rently(passive) is caused byLactate

in the labeling of lactate at C3will resultin the labeling of lactate at C3

extracellular acidificationcausesextracellular acidification

side effectscan causeside effects

neworiginatingnew

lactic acidosiscausinglactic acidosis

nauseacan causenausea

other side effects not listed belowmay causeother side effects not listed below

to the disease ( Vadakkadath Meethal and Atwood , 2010may ... contributeto the disease ( Vadakkadath Meethal and Atwood , 2010

to sore muscles the next daycan leadto sore muscles the next day

in a significant reduction in serum and tissue of liver and kidney marker enzymesresultedin a significant reduction in serum and tissue of liver and kidney marker enzymes

to muscle fatiguedo leadto muscle fatigue

lactic acidosisthus causinglactic acidosis

from glycolysisresultsfrom glycolysis

lactate to be accumulated under circumstances such as contrast - induced nephropathymay leadlactate to be accumulated under circumstances such as contrast - induced nephropathy

in improved lactate thresholdresultingin improved lactate threshold

to the NAD(P)H biphasic responsecontributesto the NAD(P)H biphasic response

acidosis in the hind gut and damage to the lining , which allows entry of dangerous bacterial products into the blood streamcausingacidosis in the hind gut and damage to the lining , which allows entry of dangerous bacterial products into the blood stream

in the hind gut and damage to the lining , which allows entry of dangerous bacterial products into the blood streamcausingin the hind gut and damage to the lining , which allows entry of dangerous bacterial products into the blood stream

fatigue ... and there is NO lactate thresholddoes ... causefatigue ... and there is NO lactate threshold

to an elevated lactate / pyruvate ratioleadingto an elevated lactate / pyruvate ratio

to rapid fatigue if the lactate is not removed it should beleadsto rapid fatigue if the lactate is not removed it should be

to rapid fatigue if the lactate is not removedleadsto rapid fatigue if the lactate is not removed

pain when it accumulates in musclescan causepain when it accumulates in muscles

muscle fatigue and paincan causemuscle fatigue and pain

fatiguecausesfatigue

fatiguecan causefatigue

fatiguecausesfatigue

fatiguedoes ... causefatigue

to muscle exhaustionleadingto muscle exhaustion

post - exercise sorenessdoes ... causepost - exercise soreness

to lactic acidosismay leadto lactic acidosis

lactic acidosiscauselactic acidosis

to a decreased pH valueleadsto a decreased pH value

muscle fatiguedoes ... causemuscle fatigue

a decrease in rumencausinga decrease in rumen

an acidic microenvironment(passive) caused byan acidic microenvironment

to oxidative metabolismcontributedto oxidative metabolism

by virtue of its acidic pHcausesby virtue of its acidic pH

acidosis only when the ATP generated during glycolysis / fructolysis is consumedcausesacidosis only when the ATP generated during glycolysis / fructolysis is consumed

from glycolysisresultingfrom glycolysis

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