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Qaagi - Book of Why

Causes

Effects

This drugmay causea serious problem called capillary leak syndrome

endothelial damageresultingin massive capillary leak syndrome

Coughcausescapillary leak syndrome possible

3 of Individualsinfluencedhad a background of capillary leak syndrome and

The toxicity of Il-2 is related to alterations in vascular permeabilityleadingto a capillary leak type of syndrome

This medicinemay causea condition called capillary leak syndrome

the physicianscontributingto the Capillary Leak Syndrome Registry

mechanismsmay causeSystemic Capillary Leak Syndrome

knownto causevascular leak syndrome

by one or more pathogens(passive) caused byvascular leak syndrome

by pathogens(passive) caused byvascular leak syndrome

Its infections ... DHF symptomscausesvascular leak syndrome

usually(passive) is ... causedCSF leak syndrome

by Interleukin-2 therapy(passive) caused byvascular leak syndrome

Estrogen retention appearsto resultfrom a vascular leak syndrome

Although interleukin-2 ( IL-2 ) has been used in antitumor therapy , it is associated with endothelial cell injuryleadingto vascular leak syndrome ( VLS

a result of severe toxicitycan leadto capillary leak syndrome

the increased vascular permeabilityleadsto a capillary leak syndrome

an increased vascular permeabilityleadingto capillary leak syndrome

Systemic Inflammatory Response to Stresscausingcapillary leak syndrome

the endothelial liningleadingto capillary leak syndrome

The mechanismcausingthe capillary leak syndrome

any drugcausingCAPILLARY LEAK SYNDROME

other drugscauseCAPILLARY LEAK SYNDROME

activationcausingcapillary leak syndrome

vascular permeabilitycausinga capillary leak syndrome

THERAPYcausesCAPILLARY LEAK SYNDROME

to plasma proteinsleadingto capillary leak syndrome

Pulmonary edemacan resultfrom capillary leak syndrome

suggestingmay leadto capillary leak syndrome

PREDNISONE ... other drugscauseCAPILLARY LEAK SYNDROME

physical stressleadingto capillary leak syndrome

based on IL-2 tendto causecapillary leak syndrome

RADIATION THERAPY ... other drugscauseCAPILLARY LEAK SYNDROME

Harm to the endothelial layer of blood vessels brought on by these inflammatory mediatorscan resultin capillary leak syndrome

posterior reversible encephalopathy syndromemay causecapillary leak syndrome

that endothelial cell damage due to administration of high doses of follicle - stimulating hormone and luteinizing hormone during pituitary suppression with a gonadotropin - releasing hormone analogcausesa capillary leak syndrome

the sealcausecapillary leaks

pulmonary inflammationmay leadto capillary leak

capillariesleadingto capillary leak

the body to keep excess fluidcausesthe body to keep excess fluid

hypotension and reduced organ perfusioncauseshypotension and reduced organ perfusion

to the patients deathleadto the patients death

similar swelling episodesmay causesimilar swelling episodes

low blood pressure and fluid retentioncauseslow blood pressure and fluid retention

to peripheral edema and acute renal failureleadingto peripheral edema and acute renal failure

to acuteleadingto acute

to hemorrhage , shock , end - organ failure and deathcan leadto hemorrhage , shock , end - organ failure and death

to deathleadingto death

to acute renal failureleadingto acute renal failure

from rupture of the alveoli or respiratory airwaymay resultfrom rupture of the alveoli or respiratory airway

respiratorymay causerespiratory

in severe lower limb deformitymay resultin severe lower limb deformity

to acute renal failure in patients with acute promyelocytic leukemialeadingto acute renal failure in patients with acute promyelocytic leukemia

to significant side effectscan leadto significant side effects

to death in 2 of 3 patients treated at that doseleadingto death in 2 of 3 patients treated at that dose

leakage of fluid from blood vessels ... tissue swelling and a drop incan causeleakage of fluid from blood vessels ... tissue swelling and a drop in

to considerable side effectsmight leadto considerable side effects

to loss of intravascular fluidleadingto loss of intravascular fluid

leakage of fluid from blood vessels ... tissue swelling and a drop in blood pressurecan causeleakage of fluid from blood vessels ... tissue swelling and a drop in blood pressure

a compartment syndrome of both lower legs and a forearmcausesa compartment syndrome of both lower legs and a forearm

to severe hypotensionwill leadto severe hypotension

alsoleadsalso

to multiple organ failure and shockmay leadto multiple organ failure and shock

to multiple organ failure , shock and even deathmay leadto multiple organ failure , shock and even death

to multiple organ failure , shock and even deathmay leadto multiple organ failure , shock and even death

to multiple organ failurecan leadto multiple organ failure

in multi - organ system compromisecan resultin multi - organ system compromise

hemorrhage(passive) caused byhemorrhage

in fluid extravasationresultingin fluid extravasation

in hypotensioncan resultin hypotension

to hypotensionleadingto hypotension

ultimatelymay ... leadultimately

to intravascular depletion , hypovolemia , respiratory compromise and multi - organ failureleadsto intravascular depletion , hypovolemia , respiratory compromise and multi - organ failure

in a net movement of fluid from the intravascular compartment into tissuesresultsin a net movement of fluid from the intravascular compartment into tissues

significant non - cardiogenic pulmonary oedemacausingsignificant non - cardiogenic pulmonary oedema

in a net movement of fluid from the intravascular compartmentresultsin a net movement of fluid from the intravascular compartment

from extravasation of plasma proteins and fluidresultingfrom extravasation of plasma proteins and fluid

to peripheral edema , hypotension and renal insufficiencyleadingto peripheral edema , hypotension and renal insufficiency

hypotension and reduced organ perfusioncauseshypotension and reduced organ perfusion

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