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Deutschlehrer in Seminarensettingals Fernstudienkurse
superoxide dismutase ( SOD1 ) mutations(passive) caused byALS pathogenesis
Othersdiscoverstairlifts als
mutationscausingALS ( 7,9,14,15
the most common p97 mutantcausingIBMPFD / ALS
that modifications of a proteinCprotein connection network around the C - terminus of FUS may account for its localization in SGsinfluencingALS pathogenesis
Researchersdiscoverbiomarkers of ALS
Hundreds of mutations in the Cu / Zn superoxide dismutase ( SOD1 ) gene have been foundto causeALS
by mutations in the superoxide dismutase 1 ( SOD1 ) gene(passive) caused byALS)
by mutations in the superoxide dismutase 1 ( SOD1 ) gene(passive) caused by (ALS
by mutations in the superoxide dismutase 1 ( SOD1 ) gene(passive) caused byALS
For example , certain mutations in the SOD1 , TDP43 , FUS and C9ORF72 genes are knownto causeALS
Mutations in superoxide dismutase 1 ( SOD1 ) have been identifiedto causeALS
Hundreds of mutations in the Cu / Zn superoxide dismutase ( SOD1 ) have been foundto causeALS
Hundreds of mutations in the Cu / Zn superoxide dismutase gene have been foundto causeALS
Superoxide dismutase 1 , known as SOD1 ... foundto causeALS
A mutation in this protein , superoxide dismutase ( SOD1can causeALS
the deterioration and death of motor neurons in the spinal cord , which has been associated to mutations in copper , zinc superoxide dismutase , which is essential to life but(passive) is caused byALS
Mutations in , or over - expression of , the C9orf72 gene have been foundto causeALS
Before the discovery of TDP-43 stress granules , researchers spent 20 years studying SOD1 , the first gene discoveredcausedALS
the deterioration and death of motor neurons in the spinal cord , which has been associated to mutations in copper , zinc superoxide dismutase , which is essential to life but can become toxic(passive) is caused byALS
superoxide dismutase 1 ( SOD1 ... cellscausesALS
by mutations in the gene SOD1 ( superoxide dismutase 1(passive) caused byALS
dominant mutations in SOD1 that give toxic property to the mutant protein(passive) can be caused byALS
SOD1 mutations that produce a similar protein are knownto causeALS
Dominant mutations of the SOD1 gene ... that have been reportedto causeALS
A mutation in the gene for superoxide dismutase SOD1 , an enzyme involved in the control of oxidative stresscausesALS
by mutant genes such as SOD1 and C9ORF72(passive) caused byALS
by mutations in the superoxide dismutase 1(passive) caused by (ALS
a pathology that is similar to that of the gene TAR DNA - binding protein 43 ( TDP43 ... whose mutationscauseALS
the mutant human gene SOD1causesALS
mutations in the gene coding Cu / Zn - superoxide dismutase ( SOD1(passive) are caused byALS
by mutations in the SOD1 gene(passive) caused byALS
This discovery and later findings that mutations in the TDP-43 genecan causeALS
A mutation in the gene for superoxide dismutase 1 ( SOD1causesALS
A mutation in the gene for superoxide dismutase 1 ( SOD1causesALS
mutations in SOD1 , TDP43 and C9ORF72(passive) caused byALS
the mutation of superoxide dismutase 1(passive) is caused byALS
mutations in SOD1 or FUScauseALS
the fate of NG2 + cells in both normal mice and mice with a mutant form of the SOD1 genecausesALS
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difficulties in speaking , walking , breathing , and swallowing ... with the disease eventually being fatal in about a quarter of all patients affected each yearcausesdifficulties in speaking , walking , breathing , and swallowing ... with the disease eventually being fatal in about a quarter of all patients affected each year
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to the death of nerve cells in the brain that control voluntary movement like swallowing muscle movement speech and breathingleadsto the death of nerve cells in the brain that control voluntary movement like swallowing muscle movement speech and breathing
the nerve cells that control voluntary muscle movements , ( such as the muscles that control walking , talking , eating , and breathing ) to degenerate and eventually diecausesthe nerve cells that control voluntary muscle movements , ( such as the muscles that control walking , talking , eating , and breathing ) to degenerate and eventually die
to the death of the neurons controlling voluntary muscles resulting in progressive paralysisleadsto the death of the neurons controlling voluntary muscles resulting in progressive paralysis
the motor nerve cells that control voluntary muscle movement to gradually die , resulting in paralysis and eventually deathcausesthe motor nerve cells that control voluntary muscle movement to gradually die , resulting in paralysis and eventually death
mutationscausingmutations
the progressive degeneration of motor neurons , resulting in rapidly progressing muscle weakness and atrophy that eventually leads to partial or total paralysis ; on average , the disease is fatal within just four yearscausesthe progressive degeneration of motor neurons , resulting in rapidly progressing muscle weakness and atrophy that eventually leads to partial or total paralysis ; on average , the disease is fatal within just four years
the death of neurons that control voluntary muscles and is characterized by gradually worsening weakness , loss of motor function andcausesthe death of neurons that control voluntary muscles and is characterized by gradually worsening weakness , loss of motor function and
the death of neurons that control voluntary muscles and is characterized by gradually worsening weakness , loss of motor function and , when the individual can no longer breathe , deathcausesthe death of neurons that control voluntary muscles and is characterized by gradually worsening weakness , loss of motor function and , when the individual can no longer breathe , death
the degeneration and death of motor neurons that are responsible for controlling your voluntary muscle movementscausesthe degeneration and death of motor neurons that are responsible for controlling your voluntary muscle movements
weakness , wasting and paralysis of the muscles and limbs ... along with those muscles that control vital functions such as speech , swallowing and breathingcausesweakness , wasting and paralysis of the muscles and limbs ... along with those muscles that control vital functions such as speech , swallowing and breathing
nerve cells in the brain and the spinal cord to eventually degenerate and die , which can lead to full muscle paralysis and respiratory failurecausesnerve cells in the brain and the spinal cord to eventually degenerate and die , which can lead to full muscle paralysis and respiratory failure
A neurodegenerative disease characterized by progressive muscle weakness ... ALS ... to the loss of all voluntary movement , difficulty breathing , and ... in the end ... deathleadsA neurodegenerative disease characterized by progressive muscle weakness ... ALS ... to the loss of all voluntary movement , difficulty breathing , and ... in the end ... death
nerve degeneration , which leads to loss of muscle control , often to muscle paralysis and an inability to swallowcausesnerve degeneration , which leads to loss of muscle control , often to muscle paralysis and an inability to swallow
the progressive degeneration of motor neurons , resulting in progressive muscle weakness and atrophycausesthe progressive degeneration of motor neurons , resulting in progressive muscle weakness and atrophy
the degeneration of upper and lower motor neurons.[2 ] leading to muscle atrophy , muscle spasticity , and muscle weakness.[1causesthe degeneration of upper and lower motor neurons.[2 ] leading to muscle atrophy , muscle spasticity , and muscle weakness.[1
the degeneration of nerve cells in regions of the brain and spinal cord that control voluntary musclescausesthe degeneration of nerve cells in regions of the brain and spinal cord that control voluntary muscles
the death of neurons that control voluntary musclescausesthe death of neurons that control voluntary muscles
the death of neurons which control voluntary musclescausesthe death of neurons which control voluntary muscles
the neurons that control voluntary muscles to die which can result in the gradual weakening of the musclescausesthe neurons that control voluntary muscles to die which can result in the gradual weakening of the muscles
to deathleadsto death
progressive muscular weakness due to the degeneration of motor neurons in the brain and spinal cordcausesprogressive muscular weakness due to the degeneration of motor neurons in the brain and spinal cord
increasing muscle weakness ... inability to control movement , and problems with speaking , swallowing , and breathingcausesincreasing muscle weakness ... inability to control movement , and problems with speaking , swallowing , and breathing
increasing muscle weakness , inability to control muscle movement , and problems with speaking , swallowing , and breathingcausesincreasing muscle weakness , inability to control muscle movement , and problems with speaking , swallowing , and breathing
the motor neurons to degenerate or die , leading to progressive paralysiscausesthe motor neurons to degenerate or die , leading to progressive paralysis
the motor nerve cells that control voluntary muscle movement to gradually diecausesthe motor nerve cells that control voluntary muscle movement to gradually die
degeneration of nerve cells in the brain and spinal cord that control voluntary muscle movementcausesdegeneration of nerve cells in the brain and spinal cord that control voluntary muscle movement
progressive degeneration of the motor neurons , which control muscle movementscausesprogressive degeneration of the motor neurons , which control muscle movements
the progressive degeneration of motor neurons , resulting in rapidly advancing muscle weakness and atrophy that eventually leads to partial or total paralysis and deathcausesthe progressive degeneration of motor neurons , resulting in rapidly advancing muscle weakness and atrophy that eventually leads to partial or total paralysis and death
a progressive wasting of all voluntary muscles resulting in paralysiscausesa progressive wasting of all voluntary muscles resulting in paralysis
progressive loss of motor neurons from the brain and spinal cord , which leads to muscle weakness , paralysis , and death , usually within 2 to 5 yearscausesprogressive loss of motor neurons from the brain and spinal cord , which leads to muscle weakness , paralysis , and death , usually within 2 to 5 years
progressive loss of motor neurons from the brain and spinal cord , which leads to muscle weakness , paralysis , and death , usually within 2 to 5 yearscausesprogressive loss of motor neurons from the brain and spinal cord , which leads to muscle weakness , paralysis , and death , usually within 2 to 5 years
the neurons which control voluntary muscles to diecausesthe neurons which control voluntary muscles to die
the death of neurons controlling voluntary musclescausesthe death of neurons controlling voluntary muscles
the death of neuron cells that control voluntary musclescausesthe death of neuron cells that control voluntary muscles
to a slow degeneration of nerve cells that control muscle movements and an eventual loss of muscle controlleadsto a slow degeneration of nerve cells that control muscle movements and an eventual loss of muscle control
progressive weakness of limb , respiratory , swallowing and speaking musclescausesprogressive weakness of limb , respiratory , swallowing and speaking muscles