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Mutationsresultfrom changes in DNA A base substitution
how proofreading and mismatch repair are usedto preventbase substitutions in DNA
cytosine forms base - pairs with guanine , the conversion of cytosine to uracilcausesbase substitutions in dna
may ' mispair ' ,resultingin substitution of the ' wrong ' base into DNA
cytometrycausesDNA damage through base substitution
the derivative cells ... an agentcausesbase substitution of guanine for thymine
The chemical mutagen of choice for mouse ... an alkylating agentcausesbase substitutions in DNA
Reversion of derivative to primary cells ... an agentcausesbase substitution of adenine for thymine
Mutagenic agentcausingbase mispairing in DNA
a potent carcinogencausinga base substitution within the DNA
in a stop codon insertion or deletion of 1 or 2 base pairs loss of multiple base pairs addition of multiple base pairs effect on Proteinresultingin a stop codon insertion or deletion of 1 or 2 base pairs loss of multiple base pairs addition of multiple base pairs effect on Protein
This mutation(passive) is caused byThis mutation
an mRNA codon that matches a different amino acidcreatingan mRNA codon that matches a different amino acid
to an RNA splicingleadsto an RNA splicing
in an amino acid substitution in the protein productresultsin an amino acid substitution in the protein product
This allele(passive) is caused byThis allele
in a GLU342 to LYSresultingin a GLU342 to LYS
from methylationresultingfrom methylation
in a nonsenseresultsin a nonsense