Loading ...

Blob

Smart Reasoning:

C&E

See more*

Qaagi - Book of Why

Causes

Effects

mismatches(passive) are caused byBase substitution mutations

Qcausesbase substitution mutations

mitochondrial polymerase(passive) caused bybase - substitution mutations

realignment of the primer / template strandsleadsto a base substitution mutation

the mutagen(passive) caused bythe base substitution mutations

Some analogs might be incorporated into nucleic acids in place of the standard baseoften leadingto a base substitution mutation

Some analogs may be incorporated into nucleic acids in place of the normal baseoften resultingin a base substitution mutation

replicationwould causebase substitution mutations

that the primary role of BER is correcting base damagepreventingbase substitution mutations

substituting DNA 46 Gene Regulation Genes(passive) caused bySubstitution - mutation

that does not affect NF-1 binding ( 29 ) but abolishes the formation of the novel complex(passive) was createdA two - base substitution mutation

base tautomerismresultingin base substitution mutation

e.g. , sickle cell anemiaresultingfrom base substitution mutation

8-oxoguanine in DNA(passive) caused bybase substitution mutations

because phenotypic reversion has not been demonstrated conclusivelyto result exclusivelyfrom a specific base substitution mutation

As endogenous DNA adducts are knownto causebase substitution mutations

in exon 8(passive) was discoveredA single base substitution mutation

Cas9(passive) caused bysubstitution mutation

when one base is substituted for anotherresultswhen one base is substituted for another

from “ wobble ” pairingcan resultfrom “ wobble ” pairing

in the alteration of a single amino acidresultsin the alteration of a single amino acid

to abolish MAPK sites within the SMRT sequencedesignedto abolish MAPK sites within the SMRT sequence

the replacement of single base nucleotide with another nucleotidecausesthe replacement of single base nucleotide with another nucleotide

in a translational stopresultingin a translational stop

in an amino acid substitutionresultingin an amino acid substitution

in an alternate codonresultingin an alternate codon

to nonsense codonsleadingto nonsense codons

to alter local stem - loop structureswere designedto alter local stem - loop structures

primarily from base misincorporation or biochemical alterationoriginateprimarily from base misincorporation or biochemical alteration

in a STOP codon and thus stops translation of the sequence into a proteinresultsin a STOP codon and thus stops translation of the sequence into a protein

Multidrug Resistance(passive) Caused byMultidrug Resistance

in codon changeresultedin codon change

the same amino acid to be inserted as was found in wild - typecausesthe same amino acid to be inserted as was found in wild - type

a missense mutation in one of the polypeptide chains of hemoglobincausesa missense mutation in one of the polypeptide chains of hemoglobin

cell and tissue dysfunction with agecausecell and tissue dysfunction with age

to a C - C mismatch in the hDNA and palindromic - insertion mutationsledto a C - C mismatch in the hDNA and palindromic - insertion mutations

from induction of the SOS systemresultingfrom induction of the SOS system

in a reduced shattering phenotyperesultsin a reduced shattering phenotype

sickle cell anemia a.causingsickle cell anemia a.

the codon GAG to become GUGcausesthe codon GAG to become GUG

or abolishes the recognition site of a restriction enzymecreatesor abolishes the recognition site of a restriction enzyme

premature stop , exon 17causespremature stop , exon 17

it to code for a much shorter proteincausesit to code for a much shorter protein

in a stop codon or Mutationresultedin a stop codon or Mutation

in a stop - codon or a different amino acidresultedin a stop - codon or a different amino acid

Another disease(passive) caused byAnother disease

Blob

Smart Reasoning:

C&E

See more*