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changes in chromosome structure or number A processcauseschanges in the base sequence of the DNA Types of chromosomal mutation
DNA polymerase mutationresultsfrom a base change point mutation
DNA polymerase mutationresultsfrom a base change point mutation in a point mutation
expression ... 8 Molecular Basis of Mutation Mutationsresultfrom changes in the base sequence of DNA
8 Molecular Basis of Mutation Mutationsresultfrom changes in the base sequence of DNA
by radiation , viruses(passive) can be caused byMutation A change in the sequence of DNA
the other four casesoriginatingfrom a point mutation within the microsatellite sequence
exposuresmay causeactual mutations in the primary gene sequence
harmful mutationsresultingfrom alterations to the DNA base sequence
Single nucleotide polymorphisms ( SNPs ... genetic variationsresultsin a single base change in the DNA sequence
by errors in the replication process(passive) can be caused bychanges in the base sequence
TEMPERATURE - SENSITIVE MUTANTS Temperature - sensitive ( ts ) mutantsresultfrom alterations in the base sequence of DNA
A SNPresultsfrom a single base mutation in the DNA sequence
DNA polymerase slippagecan causeframeshift mutations in your sequence
Deletion or insertion of three or a multiple of three base pairs within coding sequencesdoes ... causeframeshift mutation
one environmental factorcould causea base sequence in DNA
Deletion or insertion of three or a multiple of three base pairs inside coding sequencesdoes ... causeframeshift mutation
A frameshift mutation iswill discoverindels Frameshift Mutation
agentscausebase substitution mutations
The virusmay causea mutation in base sequence
replicationwould causebase substitution mutations
an amino acid sequenceresultingfrom the mutations in the nucleotide sequence
Insertion and deletion mutationscan potentially causeframeshift mutation
the major adductdid ... causebase substitution mutations
a novel deleterious homozygous four - nucleotide deletioncausingframeshift mutation
any known methodcausesmutation in an amino acid sequence
Single nucleotide polymorphism ( SNPresultsfrom a base substitution mutation
Chemical change in 1 base pair of genecausespoint mutation
by the substitution of one nucleotide for another(passive) caused byPoint Mutation A mutation
by insertion(passive) caused by frameshift mutation
to the 3 ' end or inside of primer(passive) can be setThe bases to the mutation sequence
mistakescan leadto changes in the DNA sequence ( mutation
Alternate amino acid sequenceresultingfrom frameshift mutation in
that may insert between bases in DNAcausingframeshift mutation
by the substitution of a one or more DNA bases in a strand(passive) caused byPoint mutation Mutation
the premature termination codonresultingfrom the frameshift mutation
Reactive oxygen species ( ROS ) such as the hydroxyl radical , produced by numerous sources in the environment , are knownto causemutation in DNA
by PCR(passive) caused bythe base mutation
Heritable changes in phenotypedo ... resultfrom a change in DNA sequence
which ... to be able to form a stem and a loop(passive) has been designedbase sequence
to incorporation of incorrect amino acids in particular positions in the resulting proteinmay leadto incorporation of incorrect amino acids in particular positions in the resulting protein
in change in what amino acids are encoded by genesdoes ... resultin change in what amino acids are encoded by genes
in a change in the amino acid sequence of a proteinresultsin a change in the amino acid sequence of a protein
a change in a proteincan ... causea change in a protein
a change in the proteincan ... causea change in the protein
a change in a gene and a traitcan ... causea change in a gene and a trait
in a new codon still coding for the same amino acid ( see Fig . 6resultsin a new codon still coding for the same amino acid ( see Fig . 6
to genetic diseases or cancermay leadto genetic diseases or cancer
in a change of amino acid(s ) in the polypeptide coded for by that generesultsin a change of amino acid(s ) in the polypeptide coded for by that gene
in a change of amino acid(s ) in the polypeptideresultsin a change of amino acid(s ) in the polypeptide
in a new codon still coding for the same amino acidresultsin a new codon still coding for the same amino acid
in a change ofresultsin a change of
many cancers and genetic diseases(passive) are caused bymany cancers and genetic diseases
Variation(passive) is caused byVariation
in a change of aminoresultsin a change of amino
to an early stop codon mutationleadingto an early stop codon mutation
to enhanced activity of P2 as well as a heterologous promoter from M.smegmatisleadsto enhanced activity of P2 as well as a heterologous promoter from M.smegmatis
in the production of defective proteins Mutationsmay resultin the production of defective proteins Mutations
in the production of defective proteinsmay resultin the production of defective proteins
from errors that occur during DNA replicationresultfrom errors that occur during DNA replication
to increased GFP expressionleadsto increased GFP expression
in a significantly reduced promoter activity and the ability to compete for the bindingresultedin a significantly reduced promoter activity and the ability to compete for the binding
in a phenotypic changewill resultin a phenotypic change
mutation in an amino acid in a protein ( degenerate mutationmay ... causemutation in an amino acid in a protein ( degenerate mutation
the replacement of single base nucleotide with another nucleotidecausesthe replacement of single base nucleotide with another nucleotide
prematurecausingpremature
an altered amino acid sequence(passive) ultimately caused byan altered amino acid sequence
for example ... in an amino acid substitution , addition , or deletioncan resultfor example ... in an amino acid substitution , addition , or deletion
from cross - linking by UV lightresultingfrom cross - linking by UV light
in a premature stopresultsin a premature stop
changes at the translational levelcausingchanges at the translational level
an amino acid to be inserted at that codon that differs from that in the wild typecausesan amino acid to be inserted at that codon that differs from that in the wild type
in the production of altered Gsproteinresultingin the production of altered Gsprotein
cancercausecancer
in a change in structure or function of the nucleic acid or a resulting proteinresultsin a change in structure or function of the nucleic acid or a resulting protein
from tumorsoriginatingfrom tumors
to resistanceleadsto resistance
loss - of - function that are associated with disease occurrence and severitycausingloss - of - function that are associated with disease occurrence and severity
to diseasemay leadto disease
to diseasemay leadto disease