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conditionsdesignedto allow a desired amount of base pair mismatch
when mutagensis was carried outcauseda base pair mismatch in the region of proposed base pairing
the fact that Taq polymerase inconstantly adds an A to each end(passive) caused byone base pair difference
by the fact that Taq polymerase inconstantly adds an A to each end(passive) caused byone base pair difference
DNAresultingin base - pair mismatch or strand - mediated crosslinks between base pairs
Level mutations ... All those mutationsinfluenceone base pair
Dr. Romesberg and his teamdesignedanother base pair
mutagenic effectcausingbase pair changes
his teamdesignedan unnatural base pair ( UBP).[40
the differences in the melting temperature in DNAresultsfrom the instability of mismatched base pairs
advantage ... the differences in the melting temperature in DNAresultsfrom the instability of mismatched base pairs
his teamdesignedan unnatural base pair ( UBP).[57
that mediates guanine modificationresultingin base pair mismatch during replication
Second , the mismatch is in the adjacent upstream positioncontributingto extension from the mismatched base pair
Its genomecomposedof 4,016,942 base pairs
by replication errors(passive) caused bybase pair mismatches
DNA ... in whichresultfrom base pair combinations
The error sensing and error correction features , combined with the inherent accuracy that arises from the structure and chemistry of replicative polymerasescontributesto an error rate of approximately 1 base pair mismatch
pairing with adenosinecausinga base - pair mismatch
agentscausebase pair substitutions
Central BasesComposeTypical Base Pairs
mutagenscausingbase - pair substitutions
TMZ methylates guanines in DNA at the O6 positionleadingto base - pair mismatch
a double - stranded circular DNA moleculecomposedof 5,386 base pairs
by temperature(passive) caused bya mismatched base pair
some random mutationcould causea mismatched base pair
During replication , a mutation occurscausinga T - T base pair
double stranded DNAcomposedof 152,000 base pairs
by base damage in the duplex DNA(passive) caused bybase - pairs
mutationsleadingto mismatched base pairs
if unrepairedcan resultin base mismatch
Ichiro Hirao and his colleagues , including the x - y , s - x , Ds - Pa , and Ds - Px base pairs(passive) invented byunnatural base pairs
DNA replication errors(passive) mainly caused bymismatched base pairs
by replication error(passive) mainly caused bybase pairs
altcoins ... the waysetup base pairs
the building blocks of the DNA double helixcontributesbase pairs
Watson and Crick(passive) discovered bythe base pairs
by DNA replication errors(passive) mainly caused bybase pairs
Fixed Vehicle Steering Modecausingreencode mismatch
he played tennis every afternooninventedbase pairing
sickle - cell anemiacausessickle - cell anemia
protein functionmight influenceprotein function
to differences in amino acid sequenceleadingto differences in amino acid sequence
in a frameshiftresultingin a frameshift
to the 14 SNP targetsleadto the 14 SNP targets
in phenotypic consequences susceptible to selectionresultingin phenotypic consequences susceptible to selection
the conductivity significantlyinfluencesthe conductivity significantly
in only a slight perturbation of cleavage activity with a two- to fourfold reduction in the rate constantresultedin only a slight perturbation of cleavage activity with a two- to fourfold reduction in the rate constant
massive phenotypic differencescould causemassive phenotypic differences
to anomalies in the production of amino acids ... i.e. , proteins in the bodycan leadto anomalies in the production of amino acids ... i.e. , proteins in the body
A mutation within the DNA strandcausesA mutation within the DNA strand
in transitionwill resultin transition
to amino acid changesleadingto amino acid changes
in the wrong protein sequence being translatedresultingin the wrong protein sequence being translated
the wrong protein sequence being translatedresultingthe wrong protein sequence being translated
the template DNA strand(passive) caused bythe template DNA strand
no effectresultno effect
to nonsense mutantsleadingto nonsense mutants
to decreased affinity in on - target siteswill leadto decreased affinity in on - target sites
from DNA oxidation or alkylationresultingfrom DNA oxidation or alkylation
to poor base stackingleadsto poor base stacking
to ATP7A proteins that do not function properly.[6leadsto ATP7A proteins that do not function properly.[6
problems during assemblycan causeproblems during assembly
to ATP7A proteins that do not function properlyleadsto ATP7A proteins that do not function properly
during assemblycan causeduring assembly
in different amino acidresultingin different amino acid
The full size IL-32 gene(passive) is composedThe full size IL-32 gene
This case and(passive) is designedThis case and
the [ [ energy ] ] of the [ [ loopoften influencesthe [ [ energy ] ] of the [ [ loop
to stop codonleadingto stop codon
an aptamer selection strategy for your applicationdesignan aptamer selection strategy for your application
in protein coordination and RNA interaction ( 15resultin protein coordination and RNA interaction ( 15
in the serine in position 83 being changed to a phenylalanineresultsin the serine in position 83 being changed to a phenylalanine
aptamershas discoveredaptamers
to inherited diseasesleadingto inherited diseases
this ... on the list of pairs of chemical bases joined by hydrogen bonds that connect the complementary strands of a DNA molecule or of the RNA molecule that has two strandsdiscoverthis ... on the list of pairs of chemical bases joined by hydrogen bonds that connect the complementary strands of a DNA molecule or of the RNA molecule that has two strands
a custom aptamer selection strategy for your small molecule of interestcan quickly designa custom aptamer selection strategy for your small molecule of interest
a program with the best chance of establishing a sandwich pair ( a pair of aptamers that bind the same target at complementary locationscan designa program with the best chance of establishing a sandwich pair ( a pair of aptamers that bind the same target at complementary locations
aptamers with high selectivity and affinity for noroxycodone and norhydrocodonehas discoveredaptamers with high selectivity and affinity for noroxycodone and norhydrocodone
surface - enhanced Raman spectroscopy and citrulline aptamers(passive) discovered bysurface - enhanced Raman spectroscopy and citrulline aptamers