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oxidized guanines whose incorporation during repli- cationcausesbase - pair mismatching
But when the copy strand appears as a thymidine to the complementary base , the copy strand winds up pairing with adenosinecausinga base - pair mismatch
a point mutation(passive) caused bya base - pair mismatch
incomplete removal of the terminal nucleotide(passive) caused bya base - pair mismatch
CR and TR , respectively ( S3 Table(passive) was designedan artificial base pair mismatch
2 ) oxidative deamination of C ... Ucreatesbase - pair mismatch
But when it appears as a thymidine to the complementary base , it winds up pairing with adenosinecausinga base - pair mismatch
four probes ( two for −856 and two for −862createa single base pair mismatch
a highly reactive cation that methylates guanines in DNA at the O6 positioncausingbase - pair mismatch
TMZ methylates guanines in DNA at the O6 positionleadingto base - pair mismatch
to decreased affinity in on - target siteswill leadto decreased affinity in on - target sites
in low probe annealing temperaturesresultingin low probe annealing temperatures
over 3 orders of magnitude change in Kd depending on the mismatch positioncan causeover 3 orders of magnitude change in Kd depending on the mismatch position
from SNP allele variationcan resultfrom SNP allele variation
an increase in the pKa of the 7-deazaadenosine heterocyclecausesan increase in the pKa of the 7-deazaadenosine heterocycle
the template DNA strand(passive) caused bythe template DNA strand
errors(passive) caused byerrors
the conductivity significantlyinfluencesthe conductivity significantly
destabilization which , in the real cellular world , can lead to diseasecausesdestabilization which , in the real cellular world , can lead to disease
in cytotoxic and mutagenic DNA adductsresultingin cytotoxic and mutagenic DNA adducts