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the ability of diabetic DAMPsto triggerinflammasome activation
this receptor alone ... insufficientto triggerinflammasome activation
the ability of α - synuclein ( α - synto triggerinflammasome activation
Link to article on publisher 's site 26100496 Iracheta - Vellve , Arvin ; Petrasek , Jan ; Satishchandran , Abhishek ; Gyongyosi , Benedek ; Saha , Banishree ; Kodys , Karen ; Fitzgerald , Katherine A. ; Kurt - Jones , Evelyn A. ; and Szabo , Gyongyi , " Inhibition of sterile danger signals , uric acid and ATPpreventsinflammasome activation
that vacuolar escape / cytosolic localization is necessaryto triggerinflammasome activation
hypoxia(passive) caused bycalpain activation
the ability of dengue virus viroporin NS2A and NS2Bto triggerinflammasome activation
failure of the Ad5 vector aloneto triggerinflammasome activation
that the cytoprotective effects of celastrol are a result of its ability to inhibit the proteasome pathwaythereby preventinginflammasome activation
Kuhn A , Brow D. Suppressors of a cold - sensitive mutation in yeast U4 RNA define five domains in the splicing factor Prp8influencespliceosome activation
Select item 1092446514.Suppressors of a cold - sensitive mutation in yeast U4 RNA define five domains in the splicing factor Prp8influencespliceosome activation
Select item 1092446520.Suppressors of a cold - sensitive mutation in yeast U4 RNA define five domains in the splicing factor Prp8influencespliceosome activation
Lacroix S. P2X4 receptorsinfluenceinflammasome activation
Leukocytes P2X4 receptorsinfluenceinflammasome activation
2012 ) P2X4 receptorsinfluenceinflammasome activation
different danger signals(passive) triggered byInflammasome activation
Kuhn A. N. , Brow D. A. , 2000 Suppressors of a cold - sensitive mutation in yeast U4 RNA define five domains in the splicing factor Prp8influencespliceosome activation
blockade of Ca2 + influxpreventingcalpain activation
Together these data describe an unexpected and important difference in the ability of avirulent Fn and virulent SchuS4to triggerinflammasome activation
at low ATP(passive) is preventedSpliceosome activation
activation of bombesin receptors on the pancreatic acinar cellcauseszymogen activation
Thus additional signaling pathways may act independently or with Ca2 +to causezymogen activation
authors Lucia Mori Mycobacterium tuberculosispreventsinflammasome activation
Esp1 overexpression ... sufficientto triggerCdc14 activation
both the intrinsic and extrinsic pathways(passive) triggered byhemostatic activation
both ATP and L. monocytogenes(passive) triggered byinflammasome activation
the ATP levels ... an extenttriggeredinflammasome activation
Accumulation of misfolded proteinscausedinflammasome activation
tumors sharing common pathwaysleadingmekerk activation
LPS+ATP and Salmonella infectionto triggerinflammasome activation
metabolic stress products ( uric acid crystals , ATP , etc . ) and exogenous agents such as asbestoscan ... triggerinflammasome activation
A single amino acid mutationcan provokeBRAF activation
all known activators including MSU ( 13–15(passive) triggered byinflammasome activation
Supporting this idea , other crystals such such as silica and uric acid have been shownto triggerinflammasome activation
two signals via Toll - like receptors ( TLRs ) activation by endogenous or exogenous danger signals ( 29(passive) is resulted byInflammasome activation
ROS within mitochondria must initiate the mitochondrial cascade upstreamcausinginflammasome activation
poitn mutations in the kinase domain of the met proto - oncogene(passive) caused byOnkogenic activation
point mutations in the kinase domain of the met proto - oncogene(passive) caused byOnkogenic activation
Supporting this idea , other crystals such such as silica[8 ] and uric acid[9 ] have been shownto triggerinflammasome activation
direct intervention on mitochondria using a ligand of the mitochondrial benzodiazepin receptor or a protonophorecausesDEVDase activation
to activation of also HSF1leadsto activation of also HSF1
to release of the potent inflammatory cytokine IL-1beta from infected macrophagesleadingto release of the potent inflammatory cytokine IL-1beta from infected macrophages
to the maturation of caspase-1 and the processing of its substrates , IL-1β and IL-18leadsto the maturation of caspase-1 and the processing of its substrates , IL-1β and IL-18
release of IL-1βwill causerelease of IL-1β
to maturation and secretion of the proinflammatory cytokines IL-1β and IL-18 , which initiate early inflammatory responsesleadsto maturation and secretion of the proinflammatory cytokines IL-1β and IL-18 , which initiate early inflammatory responses
to the maturation of caspase-1 and processing of IL1βleadsto the maturation of caspase-1 and processing of IL1β
MMP12‐dependent emphysemacausesMMP12‐dependent emphysema
to caspase-1 activation , release of the proinflammatory cytokines , IL-1β and IL-18 and cell death in a process termed pyroptosisleadsto caspase-1 activation , release of the proinflammatory cytokines , IL-1β and IL-18 and cell death in a process termed pyroptosis
to production of proinflammatory cytokines and eventual cell deathleadsto production of proinflammatory cytokines and eventual cell death
to flaccid paralysismay leadto flaccid paralysis
to Caspase-1–dependent mitochondrial damage and block of mitophagy | PNAS PNAS October 28leadsto Caspase-1–dependent mitochondrial damage and block of mitophagy | PNAS PNAS October 28
to significant increases in the formation of 5-LOX products including leukotriene B(4also ledto significant increases in the formation of 5-LOX products including leukotriene B(4
to the secretion of pro - inflammatory cytokines such as IL-1β and IL-18 , which stimulate the adaptive immune systemleadsto the secretion of pro - inflammatory cytokines such as IL-1β and IL-18 , which stimulate the adaptive immune system
to the maturation of caspase-1 and the processing of the processing 's substrates , IL-1βleadsto the maturation of caspase-1 and the processing of the processing 's substrates , IL-1β
the scope of differential gene expression(passive) triggered bythe scope of differential gene expression
in the cleavage of effector pro - inflammatory cytokines such as pro - IL-1β and pro - IL-18 [ 24resultingin the cleavage of effector pro - inflammatory cytokines such as pro - IL-1β and pro - IL-18 [ 24
caspase-1 cleavage and IL-1β secretioncausescaspase-1 cleavage and IL-1β secretion
to activation of caspase-1 , interleukinleadsto activation of caspase-1 , interleukin
to the maturation of caspase-1 and the processing of its substrates , interleukin 1leadsto the maturation of caspase-1 and the processing of its substrates , interleukin 1
to Caspase-1- dependent mitochondrial damage and block of mitophagy , Proc Natl Acad Sci U S A. , 2014 , 111(43leadsto Caspase-1- dependent mitochondrial damage and block of mitophagy , Proc Natl Acad Sci U S A. , 2014 , 111(43
to IL-1β secretion and host cell death as wellleadsto IL-1β secretion and host cell death as well
to long - term behavioral alterations in mice injected with lipopolysaccharidecontributesto long - term behavioral alterations in mice injected with lipopolysaccharide
to caspase-1-dependent mitochondrial damage and block of mitophagy , Proceedings of the National Academy of Sciences of the United States of America 111 ( 43leadsto caspase-1-dependent mitochondrial damage and block of mitophagy , Proceedings of the National Academy of Sciences of the United States of America 111 ( 43
to a Caspase-1–dependent block of mitophagyleadsto a Caspase-1–dependent block of mitophagy
to outer hair cell hyperpolarization and frequency - selective suppression of afferent sound transmissionleadsto outer hair cell hyperpolarization and frequency - selective suppression of afferent sound transmission
in the secretion of the potent inflammatory cytokineresultedin the secretion of the potent inflammatory cytokine
to secretion of pro - inflammatory interleukinleadingto secretion of pro - inflammatory interleukin
to Caspase-1-dependent mitochondrial damage and block of mitophagy , Proceedings of the National Academy of Sciences of the United States of America , 111 ( 2014 ) 15514 - 15519leadsto Caspase-1-dependent mitochondrial damage and block of mitophagy , Proceedings of the National Academy of Sciences of the United States of America , 111 ( 2014 ) 15514 - 15519
to pro‐IL‐1β and pro‐IL‐18 cleavage by caspase 1 , resulting in IL‐1β and IL‐18 secretionleadsto pro‐IL‐1β and pro‐IL‐18 cleavage by caspase 1 , resulting in IL‐1β and IL‐18 secretion
to inhibition of signalling by independently ligated receptors | Biochemical Society Transactions | Portland Press Conferenceleadsto inhibition of signalling by independently ligated receptors | Biochemical Society Transactions | Portland Press Conference
dual recruitment of NLRC4 and NLRP3 to the same macromolecular complex Man , Si Mingcausesdual recruitment of NLRC4 and NLRP3 to the same macromolecular complex Man , Si Ming
to the transcription of a plethora of target genes that promote physiological changes associated with chemo-/radioresistance , including increasing the ability of DNA repair , the inhibition of apoptosis , and alterations of the cellular metabolismleadsto the transcription of a plethora of target genes that promote physiological changes associated with chemo-/radioresistance , including increasing the ability of DNA repair , the inhibition of apoptosis , and alterations of the cellular metabolism
to caspase-1–dependent mitochondrial damage ( 16leadsto caspase-1–dependent mitochondrial damage ( 16
to severe inflammation and recruitment of neutrophilsmay contributeto severe inflammation and recruitment of neutrophils
in IL‐1β secretion , NF‐κB activation , and consequent IL‐15 productionresultingin IL‐1β secretion , NF‐κB activation , and consequent IL‐15 production
to the cleavage of pro - caspase-1 and the subsequent processing of the bioactive form of IL-1β andleadsto the cleavage of pro - caspase-1 and the subsequent processing of the bioactive form of IL-1β and
in lymphoma cell proliferation and tumor growthresultedin lymphoma cell proliferation and tumor growth
to cell death and systemic inflammationleadingto cell death and systemic inflammation
pyroptosis , a rapid , inflammatory cell death that is caspase-1 dependent ( 52 , 66can triggerpyroptosis , a rapid , inflammatory cell death that is caspase-1 dependent ( 52 , 66
to secretion of caspase-1leadsto secretion of caspase-1