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Qaagi - Book of Why

Causes

Effects

Activation of calpains following hypoxiamay thus causeproteolysis / degeneration

by chronic demyelination in the absence of active inflammation(passive) caused byAxonal degeneration

by traumatic axonal injury(passive) may be causedaxonal degeneration

Exposure to NO " has been shownto causeaxonal degeneration

This diseasecausesaxonal degeneration

by chronic demyelination(passive) caused byAxonal degeneration

by mitochondrial and oxidative stress(passive) caused byaxonal degeneration

mitochondrial and oxidative stress(passive) caused byaxonal degeneration

Toxic exposurecausesaxonal degeneration

diseasescausingaxonal degeneration

Mutations in a P - type ATPase genecauseaxonal degeneration

has been shownto causeaxonal degeneration

the labrumcausinglabral degeneration

by optic nerve compression(passive) caused byaxonal degeneration

cause impairment of peripheral nerveresulted mainlyfrom axonal degeneration

disruption of these functionscausesaxonal degeneration

Methamphetamine ... shownto causedopaminergic degeneration

the nervescausingaxonal degeneration

The mechanism by whichcausesaxonal degeneration

by the progression of MS.(passive) caused byaxonal degeneration

ATP7A mutationscausingaxonal degeneration

by mechanical or toxic insults(passive) caused byaxonal degeneration

NF accumulationmay causeaxonal degeneration

The metabolic imbalancecan causeaxonal degeneration

the axonprovokingaxonal degeneration

MFN2 disease mutantscauseaxonal degeneration

focal demyelination and compression , disruption of microtubule assemblycausingaxonal degeneration

Vasculitis and toxic neuropathyusually causeaxonal degeneration

Experiments ... knownto causeaxonal degeneration

how lysosomal abnormalitiescould causeaxonal degeneration

lysosomal abnormalitiescould causeaxonal degeneration

disruption of microtubule assembly ... , and secondarycausingaxonal degeneration

myelination abnormalitiescausingaxonal degeneration

MAG knock - out mice ... knownto causeaxonal degeneration

by acrylamide exposure(passive) caused byAxonal degeneration

acrylamide exposure(passive) caused byAxonal degeneration

by paclitaxel(passive) caused byaxonal degeneration

doseproperly causingaxonal degeneration

paclitaxel(passive) caused byaxonal degeneration

the combination of normal Impulse traffic and NO at sites of inflammationmay causeAxonal Degeneration

inflammation(passive) caused byinflammation

in muscle wasting , sensory loss and weaknessresultsin muscle wasting , sensory loss and weakness

sensory losscausingsensory loss

severe disabilitycausessevere disability

from diffuse axonal damageresultsfrom diffuse axonal damage

to loss of bladderleadingto loss of bladder

to dysfunctionleadsto dysfunction

to multiple neurological deficitsleadingto multiple neurological deficits

disability and disease progressioncausesdisability and disease progression

in a peripheral neuropathyresultingin a peripheral neuropathy

in peripheral neuropathyresultingin peripheral neuropathy

to optic atrophyleadingto optic atrophy

to secondary demyelinationleadsto secondary demyelination

to muscle atrophyleadingto muscle atrophy

in demyelinationresultsin demyelination

permanent loss of functioncausespermanent loss of function

to loss of bladder toneleadingto loss of bladder tone

from a strokeresultingfrom a stroke

commonlyleadscommonly

CMT(passive) caused byCMT

in permanent anatomical occlusionmay resultin permanent anatomical occlusion

to retinal detachmentpotentially leadingto retinal detachment

to joint space narrowingcontributesto joint space narrowing

white matter dysfunction in the mouse central nervous systemcauseswhite matter dysfunction in the mouse central nervous system

white matter dysfunction in the mouse central nervous system causeswhite matter dysfunction in the mouse central nervous system

white matter dysfunction in the mousecauseswhite matter dysfunction in the mouse

in ataxiaresultingin ataxia

This progressive visual loss(passive) was caused byThis progressive visual loss

to neurovascular uncouplingleadsto neurovascular uncoupling

to neurovascular uncouplingleadsto neurovascular uncoupling

in blindness ( GAresultingin blindness ( GA

to abnormal joint function , pain and inflexibilityeventually leadsto abnormal joint function , pain and inflexibility

to pain , tissue adhesions , movement impairment and eventually loss of functioncan leadto pain , tissue adhesions , movement impairment and eventually loss of function

Diffuse spinal cord damage and atrophy(passive) is caused byDiffuse spinal cord damage and atrophy

the visual field losswas causingthe visual field loss

from osteoarthritis , a progressive and degenerative joint diseaseresultingfrom osteoarthritis , a progressive and degenerative joint disease

bone spurs to form , causing your spinal canal to narrow and leading to compressionalso can causebone spurs to form , causing your spinal canal to narrow and leading to compression

to blindnessleadingto blindness

to a reduction in joint space and increase of bone on bone activityleadsto a reduction in joint space and increase of bone on bone activity

lumbar or cervical paincauseslumbar or cervical pain

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