white matter dysfunction in the mouse central nervous system , Nature Medicine ( 2018causeswhite matter dysfunction in the mouse central nervous system , Nature Medicine ( 2018

white matter dysfunction in the mouse central nervous system | Nature Medicine Axel Montagne1causeswhite matter dysfunction in the mouse central nervous system | Nature Medicine Axel Montagne1

white matter dysfunction in the mouse central nervous system ” Reprinted from materials provided by USCcauseswhite matter dysfunction in the mouse central nervous system ” Reprinted from materials provided by USC

ataxia and peripheral neuropathy that resembles Friedreich ataxiacausesataxia and peripheral neuropathy that resembles Friedreich ataxia

the space(passive) created bythe space

in ataxia , pyramidal signs , peripheral neuropathy and developmental delayresultingin ataxia , pyramidal signs , peripheral neuropathy and developmental delay

white matter dysfunction in the mouse central nervous system Diffuse white - matter disease associated with small - vessel disease and dementia is prevalent in the elderlycauseswhite matter dysfunction in the mouse central nervous system Diffuse white - matter disease associated with small - vessel disease and dementia is prevalent in the elderly

neurovascular uncoupling and blood - brain barrier ( BBB ) breakdowncausesneurovascular uncoupling and blood - brain barrier ( BBB ) breakdown

from demyelination per seresultingfrom demyelination per se

to disruption of the sensory and/or motor function of the affected nerve2leadingto disruption of the sensory and/or motor function of the affected nerve2

permanent loss of functioncausespermanent loss of function

disease progression and accumulation of disability in multiple sclerosis ( MS ) and other neurodegenerative disorderscausesdisease progression and accumulation of disability in multiple sclerosis ( MS ) and other neurodegenerative disorders

to irreversible vision loss [ 24leadingto irreversible vision loss [ 24

a loss in central vision acuitycausesa loss in central vision acuity

to distortion of image and rapid loss of visionleadsto distortion of image and rapid loss of vision

to neurovascular uncoupling and limits from a 2.8 kg rectangular air mattress , sourceleadsto neurovascular uncoupling and limits from a 2.8 kg rectangular air mattress , source

to permanent neurological disability in inherited and acquired diseases of myelincontributesto permanent neurological disability in inherited and acquired diseases of myelin

to inflammation and lesion formation in the terminal fields ( Coleman , 2005may leadto inflammation and lesion formation in the terminal fields ( Coleman , 2005

to vision loss and even complete loss of sight - blindnessleadsto vision loss and even complete loss of sight - blindness

to a reduction in the number of motor neurons in the spinal cord and brain stem nucleileadingto a reduction in the number of motor neurons in the spinal cord and brain stem nuclei

disability and disease progression in a broad range of chronic and acute diseases of the central , ocular , and peripheral nervous systemscausesdisability and disease progression in a broad range of chronic and acute diseases of the central , ocular , and peripheral nervous systems

to blood flow disruption , uncoupling of neurovascular responses , brain hypoxia , metabolic stress , and neurodegeneration [ 34leadsto blood flow disruption , uncoupling of neurovascular responses , brain hypoxia , metabolic stress , and neurodegeneration [ 34

to less microglial infiltration and activation , which may also contribute to the extent of axonal loss in the CNS of EAE modelsleadsto less microglial infiltration and activation , which may also contribute to the extent of axonal loss in the CNS of EAE models

generallyresultsgenerally

by chronic oxaliplatin treatmentmay resultby chronic oxaliplatin treatment

This progressive visual loss(passive) was caused byThis progressive visual loss

myelin loss and ultimately leading to dysfunction and degeneration of connecting axons in white matter [ 38triggeringmyelin loss and ultimately leading to dysfunction and degeneration of connecting axons in white matter [ 38

in abnormal T2-weighted signal intensity ( 12resultingin abnormal T2-weighted signal intensity ( 12

to degenerative atrophyleadsto degenerative atrophy

to atrophy of the … ( More ) Evaluation of sensory function after median nerve decompression in carpal tunnel syndrome using the current perception threshold testleadingto atrophy of the … ( More ) Evaluation of sensory function after median nerve decompression in carpal tunnel syndrome using the current perception threshold test

from “ long - term stress on the skeletonresultfrom “ long - term stress on the skeleton

to discal material protrusion with radicular compressionleadsto discal material protrusion with radicular compression

from superficial lesions of the cerebral cortexresultingfrom superficial lesions of the cerebral cortex

in akinetic mutism and confinement to bedresultingin akinetic mutism and confinement to bed

impaired tactile sensation and persistent paincausesimpaired tactile sensation and persistent pain

to irrecoverable deficit and progression of disabilitycontributesto irrecoverable deficit and progression of disability

disease progression over a period of timecausingdisease progression over a period of time

conduction failure , which has a much different appearance on EDX examinationcausesconduction failure , which has a much different appearance on EDX examination

to progressive sensorimotor and autonomicleadingto progressive sensorimotor and autonomic

from a strokeresultingfrom a stroke