faulty gene silencing as a potential consequence of losses of 7q miRNAs in splenic marginal zone lymphoma ... pmid ' : 17592280 , ' text ' : ' TCL1 expression in B - cell tumors parallels its regulation in non - neoplastic B cells and can be used diagnostically as an indicator of the differentiation stage of a given B - cell tumor ... pmid ' : 17548807 , ' text ' : ' TORC2 regulates germinal center repression of the TCL1 oncoprotein to promote B cell development and inhibit transformation ... pmid ' : 17360849 , ' text ' : ' Biological action of the proto - oncogene TCL1 family and the development avenues for a suppressive drug specific for Akt , a core intracellular survival regulator.[REVIEW ] ' } , { ' pmid ' : 17178851 , ' text ' : ' Expression levels of microRNA generally inversely correlated with Tcl1 expression in chronic lymphocytic leukemia ... pmid ' : 17151114 , ' text ' : ' In EBV - negative diffuse large B - cell lymphoma and Burkitt lymphoma - derived cell lines infected in vitro with a recombinant EBV , high expression of EBNA2 inversely correlated with expression of germinal center - associated genes , BCL6 and TCL1 ... pmid ' : 16002684 , ' text ' : ' Detailed mechanism for TCL1-augmented signaling helps explain the delayed occurrence of mature T cell expansions and leukemias despite tumorigenic TCL1 dysregulation that begins in early thymocytes ... pmid ' : 15459205 , ' text ... Akt kinase activity can be inhibited by a peptide spanning the betaA strand of the proto - oncogene TCL1 ... pmid ' : 15325703 , ' text ' : ' Involved in the pathogenesis of mature leukemias and lymphomas : mature T - cell leukemia and chronic lymphocytic leukemia(review ) ' } , { ' pmid ' : 12672960 , ' text ' : ' altered expression in Burkitt lymphomas in the presence of Epstein - Barr virus ' } , { ' pmid ' : 12576313 , ' text ... results further support derivation of blastic tumors of skin from dendritic cells and demonstrate TCL1 proto - oncogene protein expression in this tumor ' } , { ' pmid ' : 12421830 , ' text ' : ' oncogene transactivation by Sp1 ' } , { ' pmid ' : 12381789 , ' text ' : ' data demonstrate that TCL1 is a powerful oncogene that , when overexpressed in both B and T cells , predominantly yields mature B cell lymphomas ' } , { ' pmid ' : 12127395 , ' text ' : ' Increased TCL1 expression correlates with PBC - ALL progression and loss of TEL expression(passive) may be caused byTCL1A deregulation
mutations in ddm1(passive) caused bytransposon deregulation
price wars among low - cost carriers ... resulting in fierce commercial competition at the expense of poor maintenance and service breakdown.[28provokedprice wars among low - cost carriers ... resulting in fierce commercial competition at the expense of poor maintenance and service breakdown.[28
price wars among low - cost carriers ... resulting in fierce commercial competition at the expense of poor maintenance and service breakdown.[26provokedprice wars among low - cost carriers ... resulting in fierce commercial competition at the expense of poor maintenance and service breakdown.[26
to extraordinary focus , depressing carrier , a deterioration in labor - management family members , a narrower margin of defense , and better costs for the patronhas ledto extraordinary focus , depressing carrier , a deterioration in labor - management family members , a narrower margin of defense , and better costs for the patron
to a drop in the level of fareshas ledto a drop in the level of fares
to schedules requiring planes to wait some time before takeoff , which seems to build up pressure on smokers to light up in unison as soon as they canhas ledto schedules requiring planes to wait some time before takeoff , which seems to build up pressure on smokers to light up in unison as soon as they can
to huge growth in traffic and huge declines in priceshas ledto huge growth in traffic and huge declines in prices
to airplane maintenance that imperils passengersledto airplane maintenance that imperils passengers
The new competitive environment(passive) created byThe new competitive environment
to a United Airlines monopolywould leadto a United Airlines monopoly
in 1979ledin 1979
to increased safety in air travelhas ledto increased safety in air travel
to the travel dystopialedto the travel dystopia
to an increase in airline fatalities perleadingto an increase in airline fatalities per
low - fare carriers to commence flightspromptedlow - fare carriers to commence flights
to far more actual and potential airline competitionhad ledto far more actual and potential airline competition
to the development of frequent flyer plansleading almost immediatelyto the development of frequent flyer plans
in a dramatic loss of air service in rural Nebraska with enplanements in our smaller cities down more than 56 percent since 1978has resultedin a dramatic loss of air service in rural Nebraska with enplanements in our smaller cities down more than 56 percent since 1978
Braniff to failcausedBraniff to fail
to deeply discounted fareshas ledto deeply discounted fares
in the late 1970ssetin the late 1970s
in both growth and diversity in the commercial aviation industryhas resultedin both growth and diversity in the commercial aviation industry