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Qaagi - Book of Why

Causes

Effects

possible mechanisms by whichcan causeautoimmunity

the ability of T cellsto causeautoimmunity

regulatory T cells - immune cellspreventautoimmunity

fewer regulatory T cells ( Tregs ) , which helppreventautoimmunity

Foxp3 + T regulatory cells ( Tregs ) helppreventautoimmunity

naive T cells into regulatory T ( Treg ) cellspreventautoimmunity

naïve T cells into regulatory T ( Treg ) cellspreventautoimmunity

The exact mechanismstriggerautoimmunity

certain mechanismsmay triggerautoimmunity

the pathophysiological mechanismstriggerautoimmunity

the molecular mechanismscausingautoimmunity

the function of the regulatory T cells ( Tregspreventautoimmunity

chronic viral infection with CMVcan triggerautoimmunity

certain immune cellscan causeautoimmunity

AB - FOXP3 + regulatory T cells ( T reg cellspreventautoimmunity

to maintain self - tolerancepreventingautoimmunity

peripheral mechanisms of tolerance ... to helppreventautoimmunity

which is controlled by undefined mechanismsto preventautoimmunity

mdl-29045828 Regulatory T cells ( Tregspreventautoimmunity

a certain infectioncan createautoimmunity

Infection by this pathogenmay triggerautoimmunity

an infection ... in turncan triggerautoimmunity

the underlying infection(passive) potentially triggered byautoimmunity

Streptococcus infection(passive) triggered byautoimmunity

the ability of ‘ modified selfto triggerautoimmunity

Splenic marginal zone B cells ... stringent tolerance mechanismsto preventautoimmunity

225 - 230 FOXP3(+ ) regulatory T cells ( T - reg cellspreventautoimmunity

OspA ... is knowto causeautoimmunity

toxins ... knowto causeautoimmunity

In healthy individuals , peripheral tolerance mechanisms keep these cells in checkto preventautoimmunity

a big one ... immune cellspreventautoimmunity

immune regulatory mechanismspreventautoimmunity

while peripheral mechanisms attemptto preventautoimmunity

several regulatory mechanismspreventautoimmunity

description " : " The instruction of the immune system to be tolerant of selfthereby preventingautoimmunity

the need to delete autoreactive T cellsthus preventingautoimmunity

immune checkpoints ... as they helpto preventautoimmunity

all autoreactive lymphocytes and therefore additional mechanisms of peripheral tolerance are requiredto preventautoimmunity

a decrease in the number of immune cells ( regulatory T cellspreventautoimmunity

The basement membrane ... self - tolerancepreventsautoimmunity

to T1D ( Type 1 Diabetesleadsto T1D ( Type 1 Diabetes

type 1 diabetes and LADAcausestype 1 diabetes and LADA

to type 1 diabetes More informationleadsto type 1 diabetes More information

At least 80 diseases are believed(passive) to be caused byAt least 80 diseases are believed

disease exacerbationto preventdisease exacerbation

human disease(passive) allegedly caused byhuman disease

in manifestations of rheumatic diseasesresultingin manifestations of rheumatic diseases

diseases such as Crohn ’s and rheumatoid arthritiscausesdiseases such as Crohn ’s and rheumatoid arthritis

to autoimmune diseases such as rheumatoid arthritis or lupuscan leadto autoimmune diseases such as rheumatoid arthritis or lupus

The inflammation is believed(passive) to be caused byThe inflammation is believed

to diseases such as atherosclerosis and diabetesleadingto diseases such as atherosclerosis and diabetes

Around 95 % of cases of type 1 diabetes(passive) are caused byAround 95 % of cases of type 1 diabetes

inflammation in the braincan causeinflammation in the brain

Lupus , Arthritis , Celiac , MS , Type 1 Diabetes , Graves ' , Thyroiditis and 100 + other diseasescausesLupus , Arthritis , Celiac , MS , Type 1 Diabetes , Graves ' , Thyroiditis and 100 + other diseases

thyroid diseases(passive) caused bythyroid diseases

once - rare diseases(passive) caused byonce - rare diseases

chronic diseases(passive) caused bychronic diseases

many diseases(passive) caused bymany diseases

The inflammation which spurs this form of joint disease(passive) is caused byThe inflammation which spurs this form of joint disease

in the inflammation of the jointsresultsin the inflammation of the joints

Autoimmune diseases : including systemic lupus erythematosus , multiple sclerosis , and rheumatoid arthritis(passive) are caused byAutoimmune diseases : including systemic lupus erythematosus , multiple sclerosis , and rheumatoid arthritis

lupus , rheumatoid arthritis , Crohn 's , multiple sclerosis , type 1 diabetes , and 100 + other diseasescauseslupus , rheumatoid arthritis , Crohn 's , multiple sclerosis , type 1 diabetes , and 100 + other diseases

to a variety of autoimmune diseasesleadingto a variety of autoimmune diseases

many autoimmune diseasescausesmany autoimmune diseases

both diabetes and rheumatoid arthritis ( RA(passive) are caused byboth diabetes and rheumatoid arthritis ( RA

diabetes , celiac disease , rheumatoid arthritis and otherscan causediabetes , celiac disease , rheumatoid arthritis and others

several disease(passive) are caused byseveral disease

A genetic disease(passive) caused byA genetic disease

the reversal of diseaseto preventthe reversal of disease

to the pathogenesis of this diseasecan ... contributeto the pathogenesis of this disease

a representative disease(passive) caused bya representative disease

thyroid disease(passive) caused bythyroid disease

a neurological disease(passive) caused bya neurological disease

a neurologic disease(passive) caused bya neurologic disease

to the destruction of pancreatic islet β cells in type 1 diabetes ( T1Dleadingto the destruction of pancreatic islet β cells in type 1 diabetes ( T1D

a chronic inflammation of the pituitary gland(passive) often caused bya chronic inflammation of the pituitary gland

to the development of diseases of the joints and kidneys , such as rheumatoid arthritis , or diseases of the circulatory or central nervous systems [ 174can leadto the development of diseases of the joints and kidneys , such as rheumatoid arthritis , or diseases of the circulatory or central nervous systems [ 174

lupus , arthritis , vasculitis , MS , fibromyalgia , Graves ' and 80 + other diseasescauseslupus , arthritis , vasculitis , MS , fibromyalgia , Graves ' and 80 + other diseases

widespread disease of the eye ( uveitiscausingwidespread disease of the eye ( uveitis

Addison 's diseasecan causeAddison 's disease

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