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Qaagi - Book of Why

Causes

Effects

Rationale : Gas trapped in alveoli at end expirationmay causeauto - PEEP

Increase exhalation timeto preventauto - PEEP

E ratio and TI of the mandatory breaths are continually being “ optimized ” by the ventilatorto preventauto - PEEP 

air trapping during mechanical ventilation(passive) is caused byAuto - PEEP

high tidal volume or end expiratory pressure , or obstructive lung diseasecausesauto - PEEP

As described previously , when TE is too short , gas - trapping may occur at the end of expirationcausingAuto - PEEP

As described previously , when TE is too short , gas - trapping may occur at the end of exhalationcausingAuto - PEEP

Low tidal volume and low respiratory rates with small inspiration to expiration ratiosmay preventauto - PEEP

In the high - PIP group , ventilation rate was reduced to 65 breaths / minto preventautomatic PEEP

overdistension or obstructive physiologycausingauto - PEEP

a simple alteration in flow patterncan createauto - PEEP

breath(passive) caused byAuto - PEEP

APRVcreatedauto peep

that ventilates the patient with a long Time High ( Thigh ) and short Time Low ( Tlowto intentionally createAuto - PEEP

the RR too muchcan causeauto - PEEP

these combined settings adjustmentsmay causeAuto - PEEP

which may be important in obstructive lung diseaseto preventauto - PEEP

the expiratory flow limitation(passive) caused byauto - PEEP

Using a preventive ventilation strategy with high flow and low respiratory rate may helppreventauto - PEEP

IE ratio and T(I ) of the mandatory breaths are continually being optimized by the ventialtorto preventauto peep

was reduced to 60 bpmto preventauto - PEEP

orderto prevent“ auto - PEEP

that prolong expiratory time during pressure support or pressure - control ) orcan causeauto - PEEP

the prolongation of inspirationcausesauto - PEEP

respiratory rate , TV , and the inspiratory - to - expiratory time ratio and inspiratory flow rates(passive) is influenced byAuto - PEEP

a ventilation modecreatesauto PEEP

severe respiratory and hemodynamic compromisecan causesevere respiratory and hemodynamic compromise

significant hemodynamic compromise and circulatory collapsecan causesignificant hemodynamic compromise and circulatory collapse

difficulty triggering the ventilator during spontaneous breathsmay therefore causedifficulty triggering the ventilator during spontaneous breaths

The increased triggering threshold(passive) caused byThe increased triggering threshold

to progressive air trappingcan leadto progressive air trapping

from expiratory flow limitationresultingfrom expiratory flow limitation

an inspiratory threshold loadcreatesan inspiratory threshold load

adverse effectscan causeadverse effects

the values obtained in the same individualcan influencethe values obtained in the same individual

9leads9

in improper ventilation when sufficient time to completely exhale is not givenmay ... resultin improper ventilation when sufficient time to completely exhale is not given

profound hypotension that should be treated by intravascular volume expansionmay causeprofound hypotension that should be treated by intravascular volume expansion

a problem for PAVcreatesa problem for PAV

in an increase in inspiratory plateau airway pressure , which may reintroduce a risk of lung barotraumaresultingin an increase in inspiratory plateau airway pressure , which may reintroduce a risk of lung barotrauma

increased intrathoracic pressurescan causeincreased intrathoracic pressures

in increased WOB , barotrauma , and hemodynamic instabilitymay resultin increased WOB , barotrauma , and hemodynamic instability

to decreased venous return and hypotensioncan also leadto decreased venous return and hypotension

Dynamic lung hyperinflation(passive) caused byDynamic lung hyperinflation

auto - PEEP by decreasing the time available for complete expiration [ 309may createauto - PEEP by decreasing the time available for complete expiration [ 309

the true pressure gradient the patient needs to overcome in order to trigger the ventilator to exceed the value anticipated at the prevailing ventilator settingscausesthe true pressure gradient the patient needs to overcome in order to trigger the ventilator to exceed the value anticipated at the prevailing ventilator settings

respiratory muscle fatigue and can cause rupture of the lung ( i.e. , pneumothoraxcausesrespiratory muscle fatigue and can cause rupture of the lung ( i.e. , pneumothorax

in higher positive end - expiratory pressurecan resultin higher positive end - expiratory pressure

to a significant increase in intrathoracic pressure , which will cause cardiovascular compromise by impaired venous return to the RA and increased pulmonary vascular resistancealso leadsto a significant increase in intrathoracic pressure , which will cause cardiovascular compromise by impaired venous return to the RA and increased pulmonary vascular resistance

in barotrauma ( pneumothorax , pneumomediastinum etccan resultin barotrauma ( pneumothorax , pneumomediastinum etc

hyperinflation and haemodynamic compromisecauseshyperinflation and haemodynamic compromise

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