Anna Dossing , Simon Tarp , +5 authors Torben Grube Christensen INTRODUCTION When participants drop out of randomised clinical trials , as frequently happens , the intention - to - treat ( ITT ) principle does not applypotentially leadingto attrition bias
to keep the loss to follow - up as low as possibleto preventattrition bias
non - random attrition in the Young Lives samplemight leadto attrition bias
degree of follow - up (to preventattrition bias
used ITT analysispreventingattrition bias
No information of numbers of withdrawals , dropouts , losses of follow upmay have ledto high attrition bias
use of an intention to treat analysis was not described or inadequate in 58 % ( 7/12 ) of the trialscontributingto an attrition bias
Drop out rates were high ( approx 30 %leadingto attrition bias
Third , although we will take various measures to improve the patient compliance , the loss to follow - up is still probably inevitable during the long - term follow - upresultingin attrition bias
D , patients lost to follow - up may not have the same risk trajectory as those remaining on trialresultingin attrition bias
The lower ratemay leadto attrition bias
attrition ( loss of participants ) discounting trial subjects or tests that did not run to conclusion(passive) is caused byAttrition bias
The dropout rate was highcould leadto attrition bias
Outcome assessment should be completeto preventattrition bias
a loss of participants discounting trial subjects / tests that did not run to completion(passive) is caused byAttrition bias
The ethics committee decision to not approach for consent in this situation may have been inappropriatecould have ledto biased attrition
Further varied and high attrition ratesmay have resultedin attrition bias
Empirical studies normally report reasons for attritionmay resultin attrition bias
mortality or migrationleadingto attrition bias
incomplete outcome dataleadingto attrition bias
The commonly used toolto preventattrition bias
Relatively high pain scores on the second and third dayslikely resultfrom attrition bias
the unequal loss of patients in the DCC group(passive) caused byan attrition bias
randomizedto preventattrition bias
those patients who were unable to mobiliseleadingto attrition bias
Additionally , treatment studies suffered from high dropout rates ,potentially resultingin attrition bias
systematic differences in withdrawal from the trial(passive) caused byAttrition bias
its early terminationmight have causedattrition bias
the missing data(passive) caused bythe attrition bias
intervention groups ( 50 % did not attend the classesresultingin attrition bias
Strategiesto preventattrition bias
attrition ... likelyto resultin attrition bias
difficulties in re - interviewing clients who exit(passive) caused byAttrition bias
to make searching easier and more effective(passive) are designedattrition bias
missing outcomes(passive) caused byattrition bias
information on those who died or moved away before thismay causeattrition bias
appointments at FQHCsmay have resultedin attrition bias
uncertainty in interpreting study resultsto createuncertainty in interpreting study results
to overestimation of the degree of consensus in the final resultscan leadto overestimation of the degree of consensus in the final results
from substantial dropout of participants and of outcome reporting bias due to a number of trials not reporting on mortality , as well as a number of other weaknesses in our evidenceoriginatingfrom substantial dropout of participants and of outcome reporting bias due to a number of trials not reporting on mortality , as well as a number of other weaknesses in our evidence
from missing outcome data and imprecise results with wide confidence intervalsresultingfrom missing outcome data and imprecise results with wide confidence intervals
from systematic differences between comparison groups in withdrawals or exclusions of participants from the results of a studyresultingfrom systematic differences between comparison groups in withdrawals or exclusions of participants from the results of a study
from high dropout rates and low use of the appmay resultfrom high dropout rates and low use of the app
estimates we report(passive) are influenced byestimates we report
to an overestimation or underestimation of the risk of these adverse effectscan leadto an overestimation or underestimation of the risk of these adverse effects
from differences in how many people in each group withdraw from the studyresultsfrom differences in how many people in each group withdraw from the study
essentially the same problem as selection bias from an analytic point of viewcreatesessentially the same problem as selection bias from an analytic point of view
essentiawwy de same probwem as sewection bias from an anawytic point of viewcreatesessentiawwy de same probwem as sewection bias from an anawytic point of view
the longitudinal estimates to be understatedleadsthe longitudinal estimates to be understated
from the unbalanced reasons for dropouts among groupsresultingfrom the unbalanced reasons for dropouts among groups
in this pattern of effectsshould resultin this pattern of effects
essentially the same cct imss as selection bias from an analytic point of viewcreatesessentially the same cct imss as selection bias from an analytic point of view
to inconsistent use of supporting explanations for judgments of attrition bias that one can find in CSRsmay leadto inconsistent use of supporting explanations for judgments of attrition bias that one can find in CSRs
from ei-resultingfrom ei-
to inconsistent use of supporting explanations for judgments of attrition bias that one can find in Cochrane reviewsmay leadto inconsistent use of supporting explanations for judgments of attrition bias that one can find in Cochrane reviews