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environmental stressescauseATP depletion in cells
by exercise(passive) caused bymuscle ATP depletion
Increased oxidative stresscausescellular ATP depletion
K ATPasecausingcellular ATP depletion
Deficiencycan resultin adenosine triphosphate ( ATP ) depletion
Alcoholcausesdegradation of ATP
apyrase treatment in vivocausingATP degradation
dynamic porescauseATP leakage
to support the Krebs Cycle of cellular energy production(passive) is designedATP Fuel
1 ) dose - dependent inhibition of glycolysis and mitochondria respiration , ... ; ( 2 ) dose - dependent GSH depletion ; and ( 3leadingto ATP depletion
mitochondrial complex II activityresultsin ATP depletion
to directly induce a decrease in mitochondrial respiratory activityleadingto ATP depletion
The Urgent price on the Plate aluminumwill promptD19ChT ATP
a decrease in oxygen and glucoseleadingto ATP depletion
energy stresscausesATP depletion
reverse ATP synthase activityresultsin ATP depletion
by impairment of glucose oxidation in the ETC system(passive) caused bythe ATP depletion
mitochondrial inhibition by NOwould resultin ATP depletion
cells ... stressescauseATP depletion
Excessive exercisecausesdepletion of ATP
hepatic mitochondrial oxidative phosphorylationleadsto ATP depletion
Mitochondrial damagecausingATP depletion
AMPK ... energy stresscausesATP depletion
The major molecular sensor for AMP level in cells ... cellular stressesresultin ATP depletion
Impaired pump function due toleadsATP depletion
metabolic stresscausingATP depletion
But under some harmful , conditions these species can causeleadsto ATP depletion
leads to uncoupling of oxidative phosphorylationresultingin ATP depletion
by mitochondria failure(passive) caused byATP depletion
protect cells from stressescauseATP depletion
oxidative phosphorylationcausingATP depletion
activities of these energy cycles(passive) may also be influenced byATP depletion
dose - dependent inhibition of glycolysis and mitochondria respirationleadingto ATP depletion
changes in protein phosphorylation and dephosphorylationmay resultfrom ATP - depletion
I inhibitionleadingto ATP depletion
Impaired glucose breakdown ... ; highly affected aerobic tissues likeleadingto ATP depletion
the factorscan causedepletion of ATP
PARP-1 activationledto ATP depletion
by PARP-1 activation(passive) caused byATP depletion
the removal of damaged mitochondria ... andleadingto ATP depletion
to intracellular accumulation of sodium , water , and calciumleadsto intracellular accumulation of sodium , water , and calcium
Necrosis(passive) is caused byNecrosis
to the loss of ion homeostasisleadingto the loss of ion homeostasis
inhibition of the PMCA ( 4 , 26 , 32can causeinhibition of the PMCA ( 4 , 26 , 32
Inactivation(passive) is caused byInactivation
to mitochondrial dysfunctionleadingto mitochondrial dysfunction
a concomitant increase in the AMPcausesa concomitant increase in the AMP
to poor functional recoverymay contributeto poor functional recovery
to reversible dysfunction of the ATP dependent sodium potassium ATPaseleadsto reversible dysfunction of the ATP dependent sodium potassium ATPase
on the other handleadson the other hand
failure of biosynthesis and ion pumps ... swelling Cytosolic freecausesfailure of biosynthesis and ion pumps ... swelling Cytosolic free
to cell death.[ican ... leadto cell death.[i
to cell deathcan ... leadto cell death
widespread musculus fibre hypoxia cell deceasecauseswidespread musculus fibre hypoxia cell decease
cellular Ca(2 + ) increase , mitochondrial injury , and apoptosis in renal tubular cellscausescellular Ca(2 + ) increase , mitochondrial injury , and apoptosis in renal tubular cells
to AMPK activation , mTORC1 inhibition , and autophagy induction as the last protective resort143leadsto AMPK activation , mTORC1 inhibition , and autophagy induction as the last protective resort143
to cell membranes that are more prone to oxidative damageleadingto cell membranes that are more prone to oxidative damage
in both apoptosis and necrosis , a reduction of ATP levels by 80 % or morecan resultin both apoptosis and necrosis , a reduction of ATP levels by 80 % or more
to the loss of ATP - dependent transmembrane ion transport and results in disturbances in ion homeostasisleadsto the loss of ATP - dependent transmembrane ion transport and results in disturbances in ion homeostasis
morphological changes in the cells , including shrinkage of the cell body and nucleuscausedmorphological changes in the cells , including shrinkage of the cell body and nucleus
to renal cell dysfunction and damagecontributesto renal cell dysfunction and damage
in membrane ion - pump failure , cellular swelling , uncoupling of oxidative phosphorylationwill resultin membrane ion - pump failure , cellular swelling , uncoupling of oxidative phosphorylation
in membrane ion - pump failure , cellular swelling , uncoupling of oxidative phosphorylation andwill resultin membrane ion - pump failure , cellular swelling , uncoupling of oxidative phosphorylation and
death of cellscausingdeath of cells
to failure of ATP dependentultimately leadsto failure of ATP dependent
inhibition of [ [ sodium ] ] transport , impairment of water balance , [ [ calciumcausesinhibition of [ [ sodium ] ] transport , impairment of water balance , [ [ calcium
to cell membrane failure and necrosis while partial ATP preservation allows the mitochondria to release Caspases which lead to apoptosisleadsto cell membrane failure and necrosis while partial ATP preservation allows the mitochondria to release Caspases which lead to apoptosis
to inhibition of apoptosis and promotion of necrotic cell deathleadsto inhibition of apoptosis and promotion of necrotic cell death
to inhibition of apoptosisleadsto inhibition of apoptosis
from milder mtDNA mutationsresultingfrom milder mtDNA mutations
cell membrane pump failure and cell deathcausescell membrane pump failure and cell death
an end to the wide variety of energy - dependent processes required to maintain cellular lifeultimately causesan end to the wide variety of energy - dependent processes required to maintain cellular life
aerobic respiration ( 2 ) integrity of cell membrane ( 3 ) production of proteins(passive) can be causedaerobic respiration ( 2 ) integrity of cell membrane ( 3 ) production of proteins
to rapid cell deathleadsto rapid cell death
cell injurycausescell injury
to failure of the sodium / potassium ion ATPase , which results in depolarization and dysfunction of the cell membrane functioncan leadto failure of the sodium / potassium ion ATPase , which results in depolarization and dysfunction of the cell membrane function
inhibition of sodium transportcausesinhibition of sodium transport
cellular swelling and cell membrane disruptioncausingcellular swelling and cell membrane disruption
to the transport inhibitionmay contributeto the transport inhibition
in both apoptosis and necrosiscan resultin both apoptosis and necrosis