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by Synta(passive) discovered byCRACM inhibitors
by EGFR up - regulation(passive) might be caused byEGFR inhibitors
Denali(passive) contributed byRIPK1 Inhibitors
by Denali(passive) contributed byRIPK1 Inhibitors
Administration ofresultsVEGF inhibitors
to inhibit the action of the enzyme aromatase , which converts androgens into estrogens within the body(passive) are designedAromatase inhibitors
breast cancercausearomatase inhibitors
to regulate glucose by manipulating a protein found in the renal system(passive) are designedSGLT2 inhibitors
to treat patients with persistently high LDL - C levels despite optimal use of statins(passive) are designedPCSK9 inhibitors
to slow the inactivation of incretin hormones GLP-1(passive) are designedDPP-4 inhibitors
Prior tasks at AstraZeneca searching for selective EGFR6?hER27 orresulted6d?7d inhibitors
to inhibit renal glucose reabsorption with the goal of lowering blood glucose(passive) are designedSGLT2 inhibitors
to control diabetes by blocking reabsorption(passive) are designedSGLT2 inhibitors
to treat type 2 diabetes(passive) are designedSGLT2 inhibitors
by co - crystallography(passive) discovered byphosphodiesterase inhibitors
to keep the protein from performing its function(passive) are designedSGLT2 inhibitors
to work with the statin class of cholesterol - reducing drugs(passive) are designedPLA2 inhibitors
to help the kidneys reduce the level of sugar in the bloodstream(passive) are designedSGLT2 inhibitors
to control diabetes by blocking reabsorption of glucose by the kidneys , impacting normal kidney function and allowing more sugar to be passed from the body through urine(passive) are designedSGLT2 inhibitors
from natural sources , including tree bark , fungi , shark muscle and cartilage , sea coral , green tea and herbs ( licorice , ginseng , cumin , garlic(passive) have been discovered Angiogenesis inhibitors
for treatment of human immunodeficiency virus-1 ( HIV-1(passive) were initially designedDDX3 inhibitors
to remove oestrogens from the blood thus removing some of the fuel necessary for breast cancer growth(passive) are designedAromatase inhibitors
to interrupt this process , prevent the formation of plaques and - assuming that amyloid formation is central to the development of Alzheimer 's - interrupt the cascade of events that lead to degeneration of neurons in the disease(passive) are designedInhibitors of BACE
to disrupt the function of the Wee1 protein kinase ( which helps to regulate the cell cycle ) and to cause tumor cells to divide without undergoing the normal DNA repair process , ultimately leading to tumor cell death(passive) are designedWee1 inhibitors
url =causesurl =
to increased vascular tone related to decreased nitric oxide productioncan leadto increased vascular tone related to decreased nitric oxide production
to an increase in D - dimer levelscontributeto an increase in D - dimer levels
alsomight ... leadalso
vascular regulation defects within cancers peoplecausevascular regulation defects within cancers people
proteinuria(passive) caused byproteinuria
TMAcan causeTMA
hypothyroidismcan causehypothyroidism
cerebrovascular events either by elevating systemic blood pressure or by damaging the cerebral vascular endotheliummight causecerebrovascular events either by elevating systemic blood pressure or by damaging the cerebral vascular endothelium
in a serious condition known as diabetic ketoacidosismay resultin a serious condition known as diabetic ketoacidosis
to DKA ( Diabetic ketoacidosis ) , a potentially fatal conditioncan leadto DKA ( Diabetic ketoacidosis ) , a potentially fatal condition
to diabetic ketoacidosis ( DKAmay leadto diabetic ketoacidosis ( DKA
diabetic ketoacidosiscan causediabetic ketoacidosis
side effects , such as joint paincan causeside effects , such as joint pain
joint pain types of side effectscan causejoint pain types of side effects
to reduction of estradiol synthesis from testosteroneleadingto reduction of estradiol synthesis from testosterone
to ketoacidosismay leadto ketoacidosis
osteoporosis and joint painmay causeosteoporosis and joint pain
to inhibition of cell growth and even cell deathcan leadto inhibition of cell growth and even cell death
muscle and joint aches and pains , as well as hot flashesmay causemuscle and joint aches and pains , as well as hot flashes
a decrease of bone mineral density that can lead to osteoporosis and increased risk of fractures in susceptible patientscan also causea decrease of bone mineral density that can lead to osteoporosis and increased risk of fractures in susceptible patients
more bone loss ( osteoporosis ) than tamoxifencan causemore bone loss ( osteoporosis ) than tamoxifen
to bone loss and osteoporosiscan leadto bone loss and osteoporosis
side effectscan causeside effects
Side effects(passive) caused bySide effects
osteoporosis , joint pain or carpal tunnel syndromecan causeosteoporosis , joint pain or carpal tunnel syndrome
to diabetic ketoacidosis , a serious condition where toxic waste builds up in the bloodmay leadto diabetic ketoacidosis , a serious condition where toxic waste builds up in the blood
to inhibition of cell proliferationleadsto inhibition of cell proliferation
The inhibition of the enzymeleadsThe inhibition of the enzyme
This class of drugs / medications known as(passive) were designedThis class of drugs / medications known as
muscle and joint paincausemuscle and joint pain
to loss of excess glucose ( and thereby excess caloriesleadto loss of excess glucose ( and thereby excess calories
alsocan ... leadalso
alsomay contributealso
to tumor remissionledto tumor remission
to much bone loss and osteoporosiscan ... leadto much bone loss and osteoporosis
bone loss , aches , and painscan causebone loss , aches , and pains
to joint paincan leadto joint pain
joint paincan causejoint pain
joint pain(passive) caused byjoint pain