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endogenous REDOX regulating enzymes and co - factors into the clarified harvestresultingin the reduction of antibody interchain disulfide bonds
it possibleto preventthe aggregation of the antibody in the affinity purification process
antibody concentration , SDS - PAGE analysisresultsAntibody Purification - Ligand Affinity Purification
Stv - C127 ... that had been usedto preventdisulfide bond formation during purification
Using hydrogen peroxideto preventantibody disulfide bond reduction during manufacturing process
while keeping costs under controlWhen designinga purification process for monoclonal antibodies ( mAbs
MabSelect SuRe and IgSelect affinity chromatography resinsdesignedfor process - scale purification of antibodies
Halis Türker BalaydınMurat Senturk Glutathione and thioredoxin systemscontributeto recombinant monoclonal antibody interchain disulfide bond reduction
Inc. - A Member of the Roche Group In CHO cell culture processing , mechanical shear during the harvest operations and subsequent release of intracellular factorsmay resultin antibody disulfide bond reduction
single campaign - use columnsdesignedfor GMP purification of monoclonal antibodies
SUPrA ™ Media UNOsphere SUPrA affinity chromatography media(passive) are designedSUPrA ™ Media UNOsphere SUPrA affinity chromatography media
Resins UNOsphere SUPrA affinity resin(passive) are designedResins UNOsphere SUPrA affinity resin
denaturation of an antibodyAdvanced Patent SearchPublication numberUS20050176109 A1Publication typeApplicationApplication numberUS 11/030,088Publication dateAug 11 , 2005Filing dateJan 7preventsdenaturation of an antibodyAdvanced Patent SearchPublication numberUS20050176109 A1Publication typeApplicationApplication numberUS 11/030,088Publication dateAug 11 , 2005Filing dateJan 7
in high specificity and low backgroundresultingin high specificity and low background
in generation of low molecule weight speciesresultsin generation of low molecule weight species
Antibody Purification UNOsphere SUPrA affinity media(passive) are designedAntibody Purification UNOsphere SUPrA affinity media
to the identification of nicastrinledto the identification of nicastrin
to increase outputdesignedto increase output
in a low HCP level without using protein A chromatographycan resultin a low HCP level without using protein A chromatography
in increased purification performance and higher safety of two - column processesresultingin increased purification performance and higher safety of two - column processes
SUPrA ™ Resin UNOsphere SUPrA affinity chromatography resins(passive) are designedSUPrA ™ Resin UNOsphere SUPrA affinity chromatography resins