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Qaagi - Book of Why

Causes

Effects

these effects in patients with X - linked severe combined immunodeficiency ... whose impaired response tocausessevere antibody deficiency

Full Text Deficiency of Adenosine Deaminase 2CausesAntibody Deficiency

B - cell defectsleadto antibody deficiency

antigen receptor repertoire diversityleadingto an antibody deficiency

thyroid ... a deregulated immune systemmay leadto an antibody deficiency

acute respiratory distresscausesantibody deficiency causes

primary immunodeficienciescausingantibody deficiency

genespredominantly causingantibody deficiencies

a number of different autoimmune disorders and diseases , including chronic lymphocytic lymphoma , multifocal motor neuropathy , and other disorderscauseantibody deficiencies

A missense mutation of CD19 in the conserved tryptophan 41 in immunoglobulin superfamily domainresultedin antibody deficiency

defects of immune cells ... gene mutationscausean antibody deficiency

a compensatory increase of competent IgM ,preventingan antibody deficiency

Overview of B - cell development and defectscausingantibody deficiency

a mutation in a tyrosine kinase gene which is essential for development for B lymphocytes(passive) caused byantibody deficiency

Many different conditionsmay causeantibody deficiency

CD81 mutation(passive) caused bythe antibody deficiency

Disorders involving B cellsresultin antibody deficiency

4.1 Factorscausingantibody deficiency

that heterozygous mutation in NFKB1can causean antibody deficiency ( CVID

gut inflammationresultsfrom antibody deficiency

two mutations(passive) caused byUGDH Antibodies ) deficiency

minor forms of host deficiencycreatingantibody deficiency diseases

The homozygous deletion of the inducible costimulator ( ICOS ) , an activation - induced member of the CD28 family on T cellscausesan antibody deficiency

Recently , dominant mutations in NFKB2 have shownto causeantibody deficiency

B cell mutationscausingselective antibody deficiency

to recurrent sinusitis , otitia and many other types of infectionsalso can leadto recurrent sinusitis , otitia and many other types of infections

recurrent infections as early as nine seven to nine months of agemay causerecurrent infections as early as nine seven to nine months of age

to an inability to clear extracellular bacterialeadsto an inability to clear extracellular bacteria

in low levels of serum IgG and IgA. Enteropathiesresultingin low levels of serum IgG and IgA. Enteropathies

the immune system from being able to fight off bacteria and virusespreventsthe immune system from being able to fight off bacteria and viruses

to absence of expected haemagglutinins , absence of germinal centres in biopsy or necropsy lymphoid material , or absence of lymphoid subpopulations in blood or marrowleadsto absence of expected haemagglutinins , absence of germinal centres in biopsy or necropsy lymphoid material , or absence of lymphoid subpopulations in blood or marrow

to recurrent bacterial infectionsleadsto recurrent bacterial infections

in persistent infection with significant loss of cardiomyocytes and documented prominent apoptotic changes in injured heartsresultsin persistent infection with significant loss of cardiomyocytes and documented prominent apoptotic changes in injured hearts

susceptibilitycan causesusceptibility

a false negative for one or more of the other blood tests listedcould causea false negative for one or more of the other blood tests listed

to primary humoral immunodeficiencies : an overviewcharacteristically leadsto primary humoral immunodeficiencies : an overview

from the CD81 deficiency in the patient ’s B cellsresultsfrom the CD81 deficiency in the patient ’s B cells

to a rare a disease – congenital agammaglobulinemiacan leadto a rare a disease – congenital agammaglobulinemia

increased neutrophil migration towards the chemokinecausedincreased neutrophil migration towards the chemokine

the maturation of lysosomesinfluencedthe maturation of lysosomes

The clinical manifestations(passive) are caused byThe clinical manifestations

to recurrent , often severe , upper and lower respiratory tract infections with encapsulated bacteria ( eg , Streptococcus pneumoniae , Haemophilus influenzaecharacteristically leadsto recurrent , often severe , upper and lower respiratory tract infections with encapsulated bacteria ( eg , Streptococcus pneumoniae , Haemophilus influenzae

to the pathogenesis of the disease ... and severe and protracted melenamay contributeto the pathogenesis of the disease ... and severe and protracted melena

in a higher sensitivity to infectious diseasesresultingin a higher sensitivity to infectious diseases

2 ) one or more of the following : 1leads2 ) one or more of the following : 1

The inflammatory complications seen in the patient , erythema nodosum , arthritis , and colitis(passive) may be caused byThe inflammatory complications seen in the patient , erythema nodosum , arthritis , and colitis

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