a number of different autoimmune disorders and diseases , including chronic lymphocytic lymphoma , multifocal motor neuropathy , and other disorderscauseantibody deficiencies
A missense mutation of CD19 in the conserved tryptophan 41 in immunoglobulin superfamily domainresultedin antibody deficiency
defects of immune cells ... gene mutationscausean antibody deficiency
a compensatory increase of competent IgM ,preventingan antibody deficiency
Overview of B - cell development and defectscausingantibody deficiency
a mutation in a tyrosine kinase gene which is essential for development for B lymphocytes(passive) caused byantibody deficiency
Many different conditionsmay causeantibody deficiency
Disorders involving B cellsresultin antibody deficiency
4.1 Factorscausingantibody deficiency
that heterozygous mutation in NFKB1can causean antibody deficiency ( CVID
gut inflammationresultsfrom antibody deficiency
two mutations(passive) caused byUGDH Antibodies ) deficiency
minor forms of host deficiencycreatingantibody deficiency diseases
The homozygous deletion of the inducible costimulator ( ICOS ) , an activation - induced member of the CD28 family on T cellscausesan antibody deficiency
Recently , dominant mutations in NFKB2 have shownto causeantibody deficiency
B cell mutationscausingselective antibody deficiency
to recurrent sinusitis , otitia and many other types of infectionsalso can leadto recurrent sinusitis , otitia and many other types of infections
recurrent infections as early as nine seven to nine months of agemay causerecurrent infections as early as nine seven to nine months of age
to an inability to clear extracellular bacterialeadsto an inability to clear extracellular bacteria
in low levels of serum IgG and IgA. Enteropathiesresultingin low levels of serum IgG and IgA. Enteropathies
the immune system from being able to fight off bacteria and virusespreventsthe immune system from being able to fight off bacteria and viruses
to absence of expected haemagglutinins , absence of germinal centres in biopsy or necropsy lymphoid material , or absence of lymphoid subpopulations in blood or marrowleadsto absence of expected haemagglutinins , absence of germinal centres in biopsy or necropsy lymphoid material , or absence of lymphoid subpopulations in blood or marrow
to recurrent bacterial infectionsleadsto recurrent bacterial infections
in persistent infection with significant loss of cardiomyocytes and documented prominent apoptotic changes in injured heartsresultsin persistent infection with significant loss of cardiomyocytes and documented prominent apoptotic changes in injured hearts
susceptibilitycan causesusceptibility
a false negative for one or more of the other blood tests listedcould causea false negative for one or more of the other blood tests listed
to primary humoral immunodeficiencies : an overviewcharacteristically leadsto primary humoral immunodeficiencies : an overview
from the CD81 deficiency in the patient ’s B cellsresultsfrom the CD81 deficiency in the patient ’s B cells
to a rare a disease – congenital agammaglobulinemiacan leadto a rare a disease – congenital agammaglobulinemia
increased neutrophil migration towards the chemokinecausedincreased neutrophil migration towards the chemokine
the maturation of lysosomesinfluencedthe maturation of lysosomes
The clinical manifestations(passive) are caused byThe clinical manifestations
to recurrent , often severe , upper and lower respiratory tract infections with encapsulated bacteria ( eg , Streptococcus pneumoniae , Haemophilus influenzaecharacteristically leadsto recurrent , often severe , upper and lower respiratory tract infections with encapsulated bacteria ( eg , Streptococcus pneumoniae , Haemophilus influenzae
to the pathogenesis of the disease ... and severe and protracted melenamay contributeto the pathogenesis of the disease ... and severe and protracted melena
in a higher sensitivity to infectious diseasesresultingin a higher sensitivity to infectious diseases
2 ) one or more of the following : 1leads2 ) one or more of the following : 1
The inflammatory complications seen in the patient , erythema nodosum , arthritis , and colitis(passive) may be caused byThe inflammatory complications seen in the patient , erythema nodosum , arthritis , and colitis