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Smart Reasoning:

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Qaagi - Book of Why

Causes

Effects

Isolated B - cell disordersresultin antibody deficiency diseases

the potentialto causeiatrogenic secondary antibody deficiency

Reported outcomes of therapeutic agents with the potentialto causeiatrogenic secondary antibody deficiency

passive transfusion of HLA or human neutrophil antigen ( HNA ) and corresponding antibodies from the donor directed against antigens of the recipient(passive) is caused byAntibody - mediated TRALI

that heterozygous mutation in NFKB1can causean antibody deficiency ( CVID

the potentialto causesecondary antibody deficiency

by HLA class I(passive) caused byAntibody - mediated TRALI

CLL and MMcan ... resultin secondary antibody deficiency

While these animals can produce functional B - cells , they can not synthesize secretory IgM ( S ) or perform immunoglobulin class - switching ( AIDleadingto complete antibody deficiency

the mechanismsresultingin antibody deficiency severity

a conditionresultsin a deficiency of IgA antibodies

by intrinsic defect of B cells and lack of T cell co - stimulation(passive) caused bya profound antibody deficiency

a conditionresultsin an IgA antibody deficiency

a conditioncausesan IgA antibody deficiency

a conditionmay leadto an IgA antibody deficiency

an important factorinfluencingantibody behavior

The lack of proteincan causedeficiency in antibodies

Factorsinfluencingantibody - mediated cytotoxicity

the factorsinfluenceantibody - mediated cytotoxicity

several rare autosomal recessive disordersresultin antibody deficiency

the diseaseleadingto antibody deficiency

defectscausingantibody deficiency

disordersleadingto antibody deficiency

that long termdoes ... causethis antibody deficiency

long term Rituximab therapydoes ... causethis antibody deficiency

Deficiency of Adenosine Deaminase 2CausesAntibody Deficiency

by B cell dysfunction(passive) caused byan antibody deficiency

primary immunodeficienciescausingantibody deficiency

2016 ) Deficiency of adenosine deaminase 2causesantibody deficiency

The mutationinfluencingantibody susceptibility

the different defects in B - cell development and functionleadto antibody deficiencies

modificationsinfluenceantibody susceptibility

by different abnormalities in the number and function of T and B lymphocytes(passive) caused byImmunoglobulin deficiency

the ability of antibodyto causeantibody - mediated

by passive transfusion of cognate antibodies and(passive) is caused byAntibody mediated

by the passive infusion of antibodies from the donor reacting with the cognate antigen of the recipient(passive) is causedAntibody mediated

researchers of Amgen and UCB(passive) led bya sclerostin - inhibiting antibody

This blood spot testwill discoverlgG antibodies

the composition of the culture media(passive) is significantly influenced byAntibody glycosylation

Scientistsdiscoverantibody that neutralizes

frequent infectionsmay causefrequent infections

from the failure by your immune system to produce sufficient antibodies in the bloodstream to fight infections , particularly those caused by bacteriaresultsfrom the failure by your immune system to produce sufficient antibodies in the bloodstream to fight infections , particularly those caused by bacteria

to recurrent bacterial infections , especially in the respiratory tractleadsto recurrent bacterial infections , especially in the respiratory tract

to a general reduction in immune responsemay leadto a general reduction in immune response

Several congenital and acquired disorderscan leadSeveral congenital and acquired disorders

in a higher sensitivity to infectious diseases resultingin a higher sensitivity to infectious diseases

to recurrent bacterial infectionsleadsto recurrent bacterial infections

to a lethal outcome [ 32leadsto a lethal outcome [ 32

to a lethal outcome [ 32].leadsto a lethal outcome [ 32].

the immune system to be severely compromised against infectionscausesthe immune system to be severely compromised against infections

trouble breathingcan causetrouble breathing

in susceptibilityresultsin susceptibility

painful inflammation of the jointscausingpainful inflammation of the joints

recurrent infectionscausingrecurrent infections

reactionscausingreactions

in recurrent bacterial infectionsresultin recurrent bacterial infections

in recurrent infections , and mental retardationresultingin recurrent infections , and mental retardation

a losscausesa loss

hypothyroidismcauseshypothyroidism

in recurrent bacterial infectionsresultin recurrent bacterial infections

recurrent bacterial infectionscauserecurrent bacterial infections

nonspecific bindingis causingnonspecific binding

fetal damagecausingfetal damage

in decreased antigen - antibody binding affinitymay resultin decreased antigen - antibody binding affinity

to the development of acute cellular rejectionleadingto the development of acute cellular rejection

in symptoms of low thyroid such as fatigue , weight gain , dry skin and constipationcan resultin symptoms of low thyroid such as fatigue , weight gain , dry skin and constipation

to a Dramatic and Rapid Response in Papillary Renal Cell Carcinoma with Sarcomatoid and Rhabdoid FeaturesLeadsto a Dramatic and Rapid Response in Papillary Renal Cell Carcinoma with Sarcomatoid and Rhabdoid Features

in a local humoral response at epithelial surfacesresultsin a local humoral response at epithelial surfaces

to assess protein profiling ( global regulation and post - translational modifications ) in cells , biopsies and biological fluidsdesignedto assess protein profiling ( global regulation and post - translational modifications ) in cells , biopsies and biological fluids

to a new class of drugscould leadto a new class of drugs

charge heterogeneitycould causecharge heterogeneity

the thyroglobulin level to be artificially suppressedwill causethe thyroglobulin level to be artificially suppressed

in improved tumor - non - tumor ratiosresultedin improved tumor - non - tumor ratios

in CD8 + lymphocyte depletion during peak SIVmac viremiaresultedin CD8 + lymphocyte depletion during peak SIVmac viremia

from the 2-doseresultingfrom the 2-dose

to increased infectionsleadsto increased infections

Immune Deficiency Syndrome"to causeImmune Deficiency Syndrome"

to increased susceptibilityleadingto increased susceptibility

to recurrent pneumonia and ear infectionsleadsto recurrent pneumonia and ear infections

CMV disease , which caused pericarditiscausedCMV disease , which caused pericarditis

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