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Qaagi - Book of Why

Causes

Effects

compound heterozygous IL1RN mutationscausingdeficiency of the interleukin-1 receptor antagonist

This drugcan causereceptor antagonist losartan causes

an environmentleadsto the upregulation of inhibitory receptors

the potassium effluxresultingfrom upregulation of acetylcholine receptors

in turnleadsto the overstimulation of NMDA receptors

to lower glucose levels by reducing the production of glucose by the liver(passive) are designedGlucagon receptor antagonists ( GRA

Caffeinecan influenceas an adenosine receptors antagonist

to lower glucose levels by reducing the production of glucose by the liver(passive) are designedGlucagon receptor antagonists

The particulardiscoveringthat NMDA receptor antagonists

hyperleptinemia(passive) caused byleptin receptors

to block the excess endothelin by various means(passive) are designedEndothelin receptor antagonists

book inhibitorscomposedof receptor antagonists

both groupsresultof receptor antagonists

Pharmacological agentsdesignedas antagonists for these receptors

It is knowncausesNMDA receptors to downregulate

to block vasoconstricting peptides , which are believed to play an important role in essential hypertension(passive) are designedEndothelin receptor antagonists

Modern neuroscience ... specifically thoseinfluenceserotinergic receptors

physiological response at a specific receptorto causephysiological response at a specific receptor

The disease(passive) is caused byThe disease

to a progressive decline in receptor activitycan leadto a progressive decline in receptor activity

to anxietycan leadto anxiety

to increased cortical glutamate releaseleadto increased cortical glutamate release

The drug(passive) could have been designedThe drug

to tolerance , whereby the liver will more quickly eliminate NMDA receptor antagonists from the bloodstreamcan leadto tolerance , whereby the liver will more quickly eliminate NMDA receptor antagonists from the bloodstream

kidney problemscan causekidney problems

birth defectsmay also causebirth defects

in depressioncausingin depression

bronchodilationcausebronchodilation

injurycauseinjury

noradrenaline release(passive) caused bynoradrenaline release

vertigocan causevertigo

These tablets(passive) can ... be composed byThese tablets

learning / memory disordercauselearning / memory disorder

a certain type of [ [ brain damagecan causea certain type of [ [ brain damage

in addition to psychosis - like results cortical injurycausein addition to psychosis - like results cortical injury

a certain type of [ [ brain damage ] ] referred to as [ [ Olney 's Lesionscan causea certain type of [ [ brain damage ] ] referred to as [ [ Olney 's Lesions

of NR1composedof NR1

a certain type of neurotoxicity or brain damage referred to as Olney 's Lesions in rodentscan causea certain type of neurotoxicity or brain damage referred to as Olney 's Lesions in rodents

a certain type of brain damage referred to as Olney 's Lesions ( in rodentscan causea certain type of brain damage referred to as Olney 's Lesions ( in rodents

rigidity and eventually deaththus causingrigidity and eventually death

sluggishness and disorientationcausesluggishness and disorientation

to a compound currently in Phase II human trialsleadingto a compound currently in Phase II human trials

any damagecauseany damage

synthesis and release of these neurotransmitters which promotescausesynthesis and release of these neurotransmitters which promotes

receptor downregulationcausereceptor downregulation

vasodilationcausevasodilation

synthesis and release of these neurotransmitters which promotes wakingcausesynthesis and release of these neurotransmitters which promotes waking

to inhibit FSH receptor pathway or the LH receptor pathwaydesignedto inhibit FSH receptor pathway or the LH receptor pathway

the opposite effectscausedthe opposite effects

in significant improvement in blood pressure and serum potassium level among patients with primary aldosteronismresultin significant improvement in blood pressure and serum potassium level among patients with primary aldosteronism

to pharmacological toleranceleadsto pharmacological tolerance

to constipationmay leadto constipation

a similar decrease in heart ratecauseda similar decrease in heart rate

in improved plasticityresultin improved plasticity

to analgesialeadingto analgesia

in more substantial painresultedin more substantial pain

in marked falls in blood pressurecan resultin marked falls in blood pressure

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