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Qaagi - Book of Why

Causes

Effects

acid produced by the body(passive) is typically caused byAnion High anion gap metabolic acidosis

a few conditionscan causean elevated anion gap without an acidosis

Zonisamidecauseshyperchloremic , non - anion gap , metabolic acidosis

acid retention(passive) is caused byHigh anion gap acidosis

The loss of bicarbonate - rich fluid in severe diarrheamay causenon - anion gap metabolic acidosis

specific drugsleadingto a high anion gap acidosis

Metabolic Acidosis Zonisamidecauseshyperchloremic , non - anion gap , metabolic acidosis

healthcare professionalscauseshyperchloremic , non - anion gap metabolic acidosis

Methanolcausesa severe anion gap acidosis

topiramatemay causenon - anion gap metabolic acidosis

Renal failurecauseshigh anion gap acidosis

The most common intoxicationsto causea high anion gap acidosis

the loss of bicarbonate from the blood(passive) is caused byA non - anion gap acidosis

60 mgcausenon - anion gap metabolic acidosis

bicarbonate losses from the renal system or gastrointestinal tract(passive) is commonly caused byNon - anion gap acidosis

conditionscauseacidosis with a normal anion gap

Iron Isoniazid Cyanide , coupled with elevated venous oxygenation Kidney failurecauseshigh anion gap acidosis

Ureteral diversioncan leadto normal anion gap acidosis

ketoacids(passive) is ... caused byan anion gap metabolic acidosis

toxic alcoholscausinganion gap metabolic acidosis

Renal failurecausesanion gap metabolic acidosis

A reduction in distal tubular proton secretion , in the absence of or out of proportion to reductions in GFRalso can leadto normal anion gap acidosis

its abilityto causeanion gap metabolic acidosis

two toxic alcoholscan causean anion gap metabolic acidosis

by lactic acid overproduction or utilization(passive) caused byanion gap metabolic acidosis

which causes increased anions such as phosphateto causean anion - gap acidosis

increased anions such as phosphateto causean anion - gap acidosis

phosphateto causean anion - gap acidosis

insulinresultingin anion - gap acidosis

A toxic dosetypically will causean anion gap acidosis

elevation in propionic acidcausesan anion gap acidosis

Renal failurecausesanion gap acidosis

by DKA(passive) caused byan anion - gap acidosis

INHcausesan anion gap acidosis

Diarrhea , renal tubular acidosis and hyperchloemiacan causenon - anion gapped acidosis

by impaired cellular respiration(passive) caused byan anion gap acidosis

The metabolites of ethylene glycol and methanol are dissociated organic acidsthereby resultingin an anion gap acidosis

Diarrhealeadsto ( anion - gap / non - anion gap

a serum osmolal gapcausea serum osmolal gap

non - anion gap metabolic acidosismay causenon - anion gap metabolic acidosis

potassium shiftcan also causepotassium shift

glycolresultsglycol

to suspicion of IPA , rather than another toxic alcohol or glycol ingestionshould leadto suspicion of IPA , rather than another toxic alcohol or glycol ingestion

an accumulation of lactatecan causean accumulation of lactate

depletion of bicarbonate anioncausesdepletion of bicarbonate anion

from accumulation of lactate , organic acids , and ketonesresultsfrom accumulation of lactate , organic acids , and ketones

increased / decreasedcan causeincreased / decreased

depletion of bicarbonate anion ... unlike ethanoland methanolcausesdepletion of bicarbonate anion ... unlike ethanoland methanol

from ketoacid productionresultingfrom ketoacid production

from HCO3- losscan resultfrom HCO3- loss

from several different mechanismscan resultfrom several different mechanisms

in : deathresultedin : death

when there is an increase of non - measured acidscausedwhen there is an increase of non - measured acids

electrostatic forces(passive) caused byelectrostatic forces

to metabolic acidosisleadsto metabolic acidosis

from a major riskresultfrom a major risk

from similarplicationsresultfrom similarplications

depletion of bicarbonate anioncausesdepletion of bicarbonate anion

for ingestion of an acid loadmay also resultfor ingestion of an acid load

from the following sequence of events ... Metabolism of ingested food produces sulfuric , phosphoric , and organic acidsresultsfrom the following sequence of events ... Metabolism of ingested food produces sulfuric , phosphoric , and organic acids

to results that do not fit the clinical pictureleadto results that do not fit the clinical picture

depletion of bicarbonate anion ... as do ethanol and methanolcausesdepletion of bicarbonate anion ... as do ethanol and methanol

at 9.6 mmol / L with a correspondingresultedat 9.6 mmol / L with a corresponding

from either hematogenous dissemination of parasites anf and dna analysis abnormal cag insert in androgen receptor and plays a significant change in bowel habitsresultsfrom either hematogenous dissemination of parasites anf and dna analysis abnormal cag insert in androgen receptor and plays a significant change in bowel habits

to G - quadruplex stabilization effect of TMPyP4 tetratosylatecontributedto G - quadruplex stabilization effect of TMPyP4 tetratosylate

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