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mutationspotentially causingamino acidic substitutions of unknown effect on the protein function
This novel alterationresultedin an Ala247Ser amino acid substitution in the protein product
missense mutationscausingamino acid change on protein level
that corresponds to missense mutationscausingamino acid change on protein level
nucleotide changes ( i.e. mutations ) at these sitescould leadto amino acid substitutions that will affect protein function
a mutation in a structural genemight causean amino acid substitution within the corresponding protein
a mutation in a structural genemay causean amino acid substitution within the corresponding protein
A SNP in a coding regioncan causeamino acid substitution ... resulting in functional modification of the protein
when different mutations ,causingdifferent amino acid substitutions in the coded protein
by translational errors(passive) are ... causedamino acid substitution errors in proteins
by translational errors(passive) are ... caused byamino acid substitution errors in proteins
the triplet codoncan resultin amino acid substitutions in protein products
mutationresultssubstitution amino acid valine glutamic proteins called
their genomesledto single amino acid substitutions in proteins of interest
nucleotide changesresultingin amino acid substitutions that impair protein function
All were missense variantscausingamino acid changes in the protein
missense , nonsense , or frameshift mutations distributed along the entire genecauseamino acid substitutions or protein truncation
one or more mutationscauseamino acid substitutions in the protein sequence
other mutationscausingamino acid substitutions in the cyp51A protein
Resistance to pyrethroids ... mutations in the VGSC genecauseamino acid substitutions in the channel protein
polymorphism ( C1858 Tcausingan amino acid substitution ( R620W ) in the lymphoid protein
missensecan resultin amino acid substitution on protein sequence
A single - nucleotide polymorphism ( C1858 Tcausingan amino acid substitution ( R620W ) in the lymphoid protein
coding regionsledto amino acid substitutions in the protein sequence
single nucleotide mutationscauseamino acid substitution in the corresponding protein
All of the RYR1 mutationsresultin amino acid substitutions in the myoplasmic portion of the protein
A change of a single nucleotidecausingan amino acid substitution in the corresponding protein
SNPsresultin amino acid substitutions in the protein sequence
single nucleotide polymorphisms ( SNPs ... gene exonsresultin amino - acid substitutions in the encoded protein
bymutationcausingamino acid substitutions in theM2 protein
This syndrome is caused by a homozygous missense mutation in the CHST8 geneleadingto an amino acid substitution in the protein
a single nucleotidecausingan amino acid substitution in the corresponding protein
not all nucleotide substitutionsleadingto amino acid substitutions in the corresponding protein
I RNA editingleadsto amino acid substitutions in protein sequences
a point mutation in the gene encoding BTKcausingthe amino acid substitution C481S in the protein
editingleadsto amino acid substitutions in protein sequences
a previously undocumented mutationcausedan amino acid substitution in the SIRT1 protein
The previously undocumented mutationcausedan amino acid substitution in the SIRT1 protein
a single nucleotide polymorphism ... that was predictedto causean amino acid substitution in the protein
mutationscauseamino acid substitutions in the LRRK2 protein
2CATPasecauses2CATPase
speciation:-can causespeciation:-
the pathogenicity and transmissibility of H7N9 following experimental infection of ferrets and miceto influencethe pathogenicity and transmissibility of H7N9 following experimental infection of ferrets and mice
to a diseasemight leadto a disease
Receptor function(passive) is also influenced byReceptor function
sickle - cell disease 50causessickle - cell disease 50
sickle - cell disease 10causessickle - cell disease 10
sickle - cell diseasecausessickle - cell disease
sickle - cell disease 24causessickle - cell disease 24
in a biological change in the organismresultingin a biological change in the organism
in constitutive activation of resistance responsesresultin constitutive activation of resistance responses
to healthy haircontributesto healthy hair
viral replication or pathogenicitycan often influenceviral replication or pathogenicity
change in protein structurecauseschange in protein structure
to complete loss of its foldingcan leadto complete loss of its folding
reduced growthto causereduced growth
an inherited disease(passive) caused byan inherited disease
sickle - cell diseasecausessickle - cell disease
longer durations of non - REM sleep as well as an increased " sleep needcausedlonger durations of non - REM sleep as well as an increased " sleep need
in excessive activation of downstream signaling pathways in breast cancer , lung cancer , and other tumorsresultedin excessive activation of downstream signaling pathways in breast cancer , lung cancer , and other tumors
longer durations of non - dreaming sleep as well as an increased " sleep needcausedlonger durations of non - dreaming sleep as well as an increased " sleep need
to a decrease in functional proteinleadsto a decrease in functional protein
in a phenotypic effectwill resultin a phenotypic effect
longer durations of non - dreaming sleep as well as an increasedcausedlonger durations of non - dreaming sleep as well as an increased
in an altered phenotype which might lead to a diseasecan resultin an altered phenotype which might lead to a disease
diseasescausediseases
diseasescausediseases
systemic diseasescausesystemic diseases
necessary protein functionmay influencenecessary protein function
a conformational change in the proteincausesa conformational change in the protein
to conservative substitutions or changes at amino acid residuesleadingto conservative substitutions or changes at amino acid residues
decreased ( e.g. , null mutations ... protein function or increased protein functioncausedecreased ( e.g. , null mutations ... protein function or increased protein function
in conformational variation of the CYP1B1 protein and thus causing downregulation of activity or change in function of the enzymeresultingin conformational variation of the CYP1B1 protein and thus causing downregulation of activity or change in function of the enzyme
in loss of protein functionresultin loss of protein function
from a single nucleotide exchange in the encoding generesultingfrom a single nucleotide exchange in the encoding gene
from non - synonymous nucleotide changesresultingfrom non - synonymous nucleotide changes
to decreased protein stabilitycontributedto decreased protein stability
to the changes in protein activities or transport specificitiescould contributeto the changes in protein activities or transport specificities
to the hydrostatic pressure adaptation of protein - protein interactions or ligand bindingmay also contributeto the hydrostatic pressure adaptation of protein - protein interactions or ligand binding
in increased bindingresultin increased binding