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Qaagi - Book of Why

Causes

Effects

by frameshift , nonsense , and splice - site mutations(passive) caused byHaploinsufficiency mutations

frameshift , nonsense , and splice - site mutations(passive) caused byhaploinsufficiency mutations

frameshift , nonsense , and splice - site mutations , which lead to failure to synthesize the products of one COL1A1 allele(passive) caused byhaploinsufficiency mutations

by cancer Chromosome(passive) caused by Carcinogenesis Mutations

et descausesdes mutations

ionizing radiations and toxic substances ... pregnancycan provokegenatic mutations

II Lescausesdes mutations

harmful mutationscausesbeneficial mutations

large populations ... more likelyto discoverbeneficial mutations

by radiation(passive) caused bybeneficial mutations

by natural selection(passive) caused bybeneficial mutations

natural selectionwill causebeneficial mutations

spacecausesbeneficial mutations

enoughto causebeneficial mutations

variationto causebeneficial mutations

mutantsto discoverbeneficial mutations

the insecticidecould causebeneficial mutations

The viruswas causingaberrant mutations

toxic wastecausingbeneficial mutations

the indirectly selected genomes ... variable enoughto discoverbeneficial mutations

the approachcan ... causeundesirable mutations

some other factorcausesfavorable mutations

1)Can(passive) be causedD. Mutations

by stress(passive) caused byD. mutations

Pressure to survivedoes ... causefavorable mutations

also(passive) are ... discoveredmTOR mutations

a loss of genetic information(passive) was caused bybeneficial mutation

by a loss of genetic information(passive) was caused bybeneficial mutation

that scientists and doctors do not knowcausesCDKL5 mutations

by whole - exome sequencing(passive) discovered byMMP20 mutations

errors that occur when DNA copies itself , the adaptation of a species to its environment or exposure to mutagenic agents like radiation(passive) can be caused byMutations

genetic drift or insertions of genetic mobile elements(passive) caused bydeleterious mutations

Mutations ... mutagens ( chemicals ... ) , as well as errors from cell replicationcausemutations

the environmentcausesadvantageous mutations

many of whichcan causedeleterious mutations

The free radicals in turn damage large molecules such as proteins and DNA Damage to DNAcausesmutations

to background radiation for longercausesdeleterious mutations

these substancescan causedeleterious mutations

random processes or mutation enhancing agents ( like chemicals or radiation(passive) caused bymutations

potent environmental carcinogens(passive) are caused byExogenous mutations

ADE neurodegeneration(passive) caused byADE neurodegeneration

hypoparathyroidismcausehypoparathyroidism

replication defectscausereplication defects

in beneficial functionresultin beneficial function

to changes that improved organismsleadingto changes that improved organisms

to diversity losshave contributedto diversity loss

increase of informationcausingincrease of information

to an organism being more fit for the environment and thus having increased " fitnessleadingto an organism being more fit for the environment and thus having increased " fitness

to improved speciesleadingto improved species

to greater fitnessleadingto greater fitness

to novel functionsleadto novel functions

life to get more complexcausedlife to get more complex

to a new regulated metabolic pathwayleadingto a new regulated metabolic pathway

to greaterleadingto greater

deleterious mutations and adaptation(passive) caused bydeleterious mutations and adaptation

to drug resistanceleadingto drug resistance

to an organismwould leadto an organism

to novel , useful structures and processesleadto novel , useful structures and processes

in more offspringresultin more offspring

to genetic loadwould leadto genetic load

to parallel mutationsleadsto parallel mutations

on the other handresulton the other hand

to less fit organismsleadto less fit organisms

to improved varieties and better cropswould leadto improved varieties and better crops

howevercould causehowever

the mutants to better survive in their environmentcausethe mutants to better survive in their environment

in a loss of information.2,3resultin a loss of information.2,3

in a higher life formresultedin a higher life form

a growing term because ... while the deleterious mutations mainly contribute to the population reduction term becausecontributea growing term because ... while the deleterious mutations mainly contribute to the population reduction term because

to increased survivalleadingto increased survival

to novel structures and functions over millions of yearsleadingto novel structures and functions over millions of years

to speciationleadingto speciation

to speciation Speciation Speciationleadto speciation Speciation Speciation

to an organism being more fit for the environmentleadingto an organism being more fit for the environment

in pointsresultin points

in improved plants and animalsresultin improved plants and animals

in more food and more progenyresultin more food and more progeny

clonal interferencecausingclonal interference

to fixation in recent timeleadto fixation in recent time

to the polymorphism datacontributeto the polymorphism data

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