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Smart Reasoning:

C&E

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Qaagi - Book of Why

Causes

Effects

by a tumor of the pituitary gland(passive) when caused byCushings disease Cushings syndrome

an immune checkpoint inhibitor combination(passive) caused byTransient pituitary ACTH - dependent Cushing syndrome

by adrenal adenomas(passive) caused byACTH - independent Cushing 's syndrome

A rare bilateral adrenal defectcausingACTH - independent Cushing syndrome

Disease descriptionA rare bilateral adrenal defectcausingACTH - independent Cushing syndrome

descriptionA rare bilateral adrenal defectcausingACTH - independent Cushing syndrome

Bilateral adrenocortical adenomascausingACTH - independent Cushing 's syndrome

adrenocortical tumors or hyperplasias(passive) is caused byACTH - independent Cushing 's syndrome

adrenal adenomas and carcinomas(passive) usually caused byACTH - independent Cushing syndrome

adrenal adenomas and carcinomas(passive) is usually caused byACTH - independent Cushing syndrome

by PPNAD(passive) caused byan ACTH - independent Cushing?s syndrome

by too much cortisol(passive) is causedCushings Syndrome ( hypercortisolism

excess production of glucocorticoid from adrenocortical tumors and hyperplasias , which leads to metabolic disorders(passive) is caused byAdrenal Cushing 's syndrome

a Fas mutation that impairs lymphocyte apoptosis(passive) caused byautoimmune lymphoproliferative syndrome

by a unilateral adrenal tumor(passive) caused byendogenous Cushings syndrome

a unilateral adrenal tumor(passive) caused byendogenous Cushings syndrome

a homozygous null FAS ligand ( FASLG ) mutation(passive) caused byAutoimmune lymphoproliferative syndrome

by too much cortisol hormone(passive) caused byCushings Syndrome

the over production of cortisol from the adrenal cancerhad causedCushings syndrome

a tumor on either the pituitary or adrenal gland(passive) is caused byCushings Syndrome

by a pituitary tumor(passive) caused byCushings syndrome

a pituitary tumorcausedCushings Syndrome

by a pituitary tumor(passive) often caused byCushings syndrome

a cortisol - secreting adrenal adenomacausingCushings syndrome

by the pituitary gland or for those with a tumor on their adrenal gland(passive) is causedCushings syndrome

an adrenal tumorwas causingCushings syndrome

An adrenal tumorcausingCushings syndrome

by a tumor on the pituitary gland(passive) caused byCushings syndrome

by a pituitary gland tumor(passive) caused byCushings syndrome

by the pituitary gland or for those with a tumor(passive) is causedCushings syndrome

too much cortisol(passive) is caused byCushings syndrome

by too much cortisol(passive) caused byCushings syndrome

Too much cortisolcan causeCushings syndrome

by both pituitary and adrenal tumours(passive) caused byCushings syndrome

the cortisol productioncan causeCushings syndrome

cortisol productionmay causeCushings syndrome

A tumor on one or more of your adrenal glandscan also causeCushings Syndrome

long - term exposure to too much cortisol , a hormone that your adrenal gland makes(passive) is caused by Cushings syndrome

long - term exposure to too much cortisol , a hormone that your adrenal gland makes(passive) is caused byCushings syndrome

excess steroid production in the bodymay ... causeCushings syndrome

weight gaincan causeweight gain

from other resultsresultingfrom other results

the adrenal glands to make cortisolcausesthe adrenal glands to make cortisol

dry eye and dry mouth because they body attacks the salivary glands and lacrimal glands reducing the production of saliva and tearscausesdry eye and dry mouth because they body attacks the salivary glands and lacrimal glands reducing the production of saliva and tears

alsocan ... causealso

vascular thrombosis and pregnancy losscausesvascular thrombosis and pregnancy loss

severe joint pain ... among other symptomscausessevere joint pain ... among other symptoms

to dry eyes and mouthleadsto dry eyes and mouth

abnormal blood clotscausesabnormal blood clots

excessive dryness throughout the bodycausesexcessive dryness throughout the body

excessive cortisol levels(passive) caused byexcessive cortisol levels

from the systemic effect of peptide secretionresultingfrom the systemic effect of peptide secretion

tightening of the blood vessels in some parts of the body , such as fingers and legs , nose and earscausestightening of the blood vessels in some parts of the body , such as fingers and legs , nose and ears

to central obesityalso leadsto central obesity

dry eyes and dry mouthcausesdry eyes and dry mouth

from increased ACTH secretionresultsfrom increased ACTH secretion

alsocausesalso

inflammation in the kidney ... causing damage to glomeruli , which results in proteinuria ( protein in the urinecausesinflammation in the kidney ... causing damage to glomeruli , which results in proteinuria ( protein in the urine

some areas of the body , such as fingers , toes and ears ... to feel numb and cool in response to cold temperatures or stresscausessome areas of the body , such as fingers , toes and ears ... to feel numb and cool in response to cold temperatures or stress

alsocan ... causealso

alsocan ... leadalso

alsocausesalso

to pathologic fractures , precocious puberty , and numerous hyperfunctional endocrinopathies.5leadsto pathologic fractures , precocious puberty , and numerous hyperfunctional endocrinopathies.5

from excessiveresultsfrom excessive

obesitycausesobesity

high levels of cortisol , which can be the pressure hormone within your bloodcauseshigh levels of cortisol , which can be the pressure hormone within your blood

those for paincan causethose for pain

from an excess of the cortisol hormoneresultsfrom an excess of the cortisol hormone

from chronic excess cortisol secretionresultsfrom chronic excess cortisol secretion

the weight gain is many of thosecausesthe weight gain is many of those

the bodycan causethe body

alsocan ... leadalso

alsomay ... leadalso

alsocan ... resultalso

complicationsresultingcomplications

to weight gainleadsto weight gain

my weight gaincausedmy weight gain

in deathcan resultin death

weight gain in the face and upper bodycausesweight gain in the face and upper body

in excessive production of cortisol by the adrenal glandsresultsin excessive production of cortisol by the adrenal glands

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Smart Reasoning:

C&E

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