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Qaagi - Book of Why

Causes

Effects

a single nucleotide deletion in the TBG gene Departments of Medicine and Pediatrics , University of Chicago , IL 60637 Metabolism 40:1231(passive) caused byComplete thyroxine - binding globulin ( TBG ) deficiency

corticosteroid - binding globulin deficiency - caused by mutations in the SERPINA6 gene More than 10 mutations in the SERPINA6 gene have been foundto causecorticosteroid - binding globulin deficiency

mutations in the SERPINA7 gene More than 25 mutations in the SERPINA7 gene(passive) caused byinherited thyroxine - binding globulin deficiency

Defects in cortisol binding globulincan causecorticosteroid - binding globulin deficiency

A novel mutationcausingcomplete deficiency of thyroxine binding globulin

Blindness disease(passive) caused byBlindness disease

The major disease(passive) caused byThe major disease

O.OвMalley , P. e. 3 - 68 Disease(passive) caused byO.OвMalley , P. e. 3 - 68 Disease

Some infants who undergo serum testing because of " low T4 , non - elevated TSH " screening test results(passive) will be discoveredSome infants who undergo serum testing because of " low T4 , non - elevated TSH " screening test results

due to hypothyroidismcan resultdue to hypothyroidism

in slow metabolic activity resulting in slowing of lipid metabolism which increases serum cholesterol and triglyceride levels making the patient at risk for atherosclerosis and cardiac disorderswill resultin slow metabolic activity resulting in slowing of lipid metabolism which increases serum cholesterol and triglyceride levels making the patient at risk for atherosclerosis and cardiac disorders

proteins to not be deposited as effectively in the tissuescausesproteins to not be deposited as effectively in the tissues

hypothyroidism.[98][99 ] Xq22.2 2CEO​ , 2RIV​causeshypothyroidism.[98][99 ] Xq22.2 2CEO​ , 2RIV​

confusion(passive) caused byconfusion

in symptoms which range from fatigue to weight gain to depression and so onmay resultin symptoms which range from fatigue to weight gain to depression and so on

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