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Qaagi - Book of Why

Causes

Effects

Lack of iodinewill causegoiter , a thyroid deficiency disease

by mutations(passive) caused bycongenital adrenal hyperplasia 21-hydroxylase deficiency

by iodine deficiency or an autoimmune disease(passive) caused byhypothyroidism deficiency in thyroxine

by iodine deficiency(passive) caused byhypothyroidism deficiency in thyroxine

a lack of selenium or zinc(passive) caused bya thyroid receptor deficiency

TPO mutations with residual activity(passive) caused byMild thyroid peroxidase deficiency

For some lactose intolerant people , even tiny amounts of lactose that are found in thyroid medications can be an issuecausingimpaired absorption of thyroid medications

when the thyroid gland does not(passive) is causedCongenital Hypothyroidism?Congenital hypothyroidism

Estrogen dominancecausingexcess TBG thyroid binding globulin

by mutations in the LEP gene(passive) is caused byCongenital leptin deficiency

mutations in the LEP gene(passive) is caused byCongenital leptin deficiency

this mutationcan causecongenital leptin deficiency

genescausedcongenital leptin deficiency

high oestrogencausean increase in thyroxine binding globulin

by LEP gene mutation(passive) caused byCongenital leptin deficiency

The mutationscausecorticosteroid - binding globulin deficiency

More than 10 mutations in the SERPINA6 gene have been foundto causecorticosteroid - binding globulin deficiency

Familial euthyroid hyperthyroxinemiaresultingfrom increased thyroxine binding to thyroxine - binding prealbumin

Oral estrogens , such as those taken for birth control or hormone replacement therapycausean increase in thyroxine - binding globulin

A deficiency in thyroid stimulating hormonecausesthyroid hormone deficiency

a hashimoto diseasecausesthyroid hormone deficiency

which destroy thyroid cells and enzymescausingdeficiency of thyroid hormone

TSH deficiencycausesthyroid hormone deficiency

the thyroid glandcausingthyroid hormone deficiency

diseases of pituitary gland or hypothalamusmay causethyroid hormone deficiency

by a malfunctioning pituitary or hypothalamus(passive) is causedthyroid hormone deficiency

Underactive thyroidcausesthyroid hormone deficiency

a deficiency of iodine in the dietcan causea deficiency of thyroxine

Anavarcausesthyroid - binding globulin

Hypothyroidism , a condition in which the thyroid gland is underactiveleadsto a deficiency of thyroxine

by iodine deficiency or an autoimmune disease(passive) caused bydeficiency in thyroxine

This disturbanceleadsto thyroxine deficiency

Liu S , Liu L , Niu X , Lu D , Xia H , Yan S. A novel missense mutation ( I26 M ) in DUOXA2causingcongenital goiter hypothyroidism impairs

inadequate iodine in the diet(passive) can be caused byThyroxine deficiencies

tetany(passive) Is ... caused bytetany

in fatigue , drowsiness or a decrease in metabolismresultsin fatigue , drowsiness or a decrease in metabolism

difficulties(passive) is caused bydifficulties

difficulties(passive) can be caused bydifficulties

in a childmay resultin a child

for adults and cretinismcausesfor adults and cretinism

in a reduced clinical response to thyroid hormones.5may resultin a reduced clinical response to thyroid hormones.5

fibrin strand deposition(passive) mainly caused byfibrin strand deposition

Myxoedema in adults and cretinismcausesMyxoedema in adults and cretinism

Myxoedema in adults and cretinism in childrencausesMyxoedema in adults and cretinism in children

to miscarriagecan leadto miscarriage

Total T3 and T4 levels(passive) are influenced byTotal T3 and T4 levels

in a reduced clinical response to levothyroxine.11 Some hypothyroid patients on estrogenmay resultin a reduced clinical response to levothyroxine.11 Some hypothyroid patients on estrogen

hypothyroidismcauseshypothyroidism

Cretinism(passive) is causedCretinism

in decreased total T 4 serum levelsresultingin decreased total T 4 serum levels

the formation of a goitercan causethe formation of a goiter

from lack of iodinemay ... resultfrom lack of iodine

in symptoms which range from fatigue to weight gain to depression and so onmay resultin symptoms which range from fatigue to weight gain to depression and so on

to loss of libidocan leadto loss of libido

severe , irreversible mental and physical retardation , a condition known as cretinismcan causesevere , irreversible mental and physical retardation , a condition known as cretinism

Use thyroxinecausesUse thyroxine

to slowing of all body processes and weight gainleadsto slowing of all body processes and weight gain

Cretinism(passive) is caused byCretinism

obesitycausesobesity

to hypothyroidism , which can be treated with hormone replacementcan leadto hypothyroidism , which can be treated with hormone replacement

increased rT3 clearancecausesincreased rT3 clearance

in decreased total T4 serum levelsresultingin decreased total T4 serum levels

to decreased total T4 serum levelsleadingto decreased total T4 serum levels

in decreased total T 4 serum levelsresultingin decreased total T 4 serum levels

in decreased total t 4 serumresultingin decreased total t 4 serum

in increased levels of T4 and T3resultsin increased levels of T4 and T3

in decreasedresultingin decreased

in more triidothyronine ( T3 ) being utilizedresultingin more triidothyronine ( T3 ) being utilized

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