mechanismsleadingto its activation and release of arachidonic acid
Ceramide production ... sub - toxic doses of doxorubicinresultedin an activation of the acid sphingomyelinase ( ASM ... release of ceramide and formation of ceramide - enriched membrane platforms
when activatedcausesarachidonic acid release and the subsequent activation of the neuroinflammatory pathway via COX-2
Hypoxialedacid sphingomyelinase activation and ceramide increase in hepatocytes
Rupture of lysosomescausesrelease of lysosomal enzymes into the cytosol and activation of acid hydrolases followed by autolysis
that TNF - alpha induces sphingomyelinase hydrolysisresultingin PLA2G2A activation and arachidonic acid release
intense physical exercisecausesarachidonic acid to be released and metabolized to active prostaglandins
alternative regulatory pathwayscan leadto cPLA2 activation and arachidonic acid release
Decreased expression of Lon proteaseledto the activation of the Rcs phosphorelay system and the overproduction of colanic acid
to massive production of oxygen free radicals and oxidative injuryleadingto massive production of oxygen free radicals and oxidative injury
as a result of PKC activation elicited by both presynaptic neurotransmitter release and activation of NMDA receptors in the spinal neuronsmay ... be provokedas a result of PKC activation elicited by both presynaptic neurotransmitter release and activation of NMDA receptors in the spinal neurons
the formation of the mitogenetic metabolite 1,3-hydroxyoctadecadienoic acidthereby preventingthe formation of the mitogenetic metabolite 1,3-hydroxyoctadecadienoic acid
to DR - induced necrosis ( 174to contributeto DR - induced necrosis ( 174
to renal injury and urothelial cancerleadingto renal injury and urothelial cancer
the AP-1-dependent pathway.29negatively influencesthe AP-1-dependent pathway.29
to PR degenerationleadsto PR degeneration
to the formation of multiple eicosanoids that are involved in inflammationcan leadto the formation of multiple eicosanoids that are involved in inflammation
a destabilization of the membrane structure assumingwould causea destabilization of the membrane structure assuming