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Smart Reasoning:

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Qaagi - Book of Why

Causes

Effects

anythingcausesabnormal platelet clumping ( thrombosis

Alterations in the RBC cytoskeletoncan leadto RBC fragility ( osmotic and mechanical ) and abnormal RBC shapes

Sickle - cell anemia ... an inherited conditioncausesabnormal red blood cells ( RBCs

an inherited conditioncausesabnormal red blood cells ( RBCs

These antibodiesmay be causingabnormal breakdown of RBCs

Sickle cell anemia ... an inherited diseasecausesabnormal red blood cells ( RBCs

by a defect in the genes(passive) caused bythe abnormal shape of the RBC

mutationscausingabnormal leaf morphology

a germline - dependent female sterile mutationcausingabnormal chorion morphology in Drosophila melanogaster

by the presence of two abnormal hemoglobin S genes [ 1(passive) caused byRBC ) disorder

a germ - line dependent female - sterile mutationcausingabnormal chorion morphology in Drosophila melanogaster

Overexpression of mutant forms of MreB inhibited cell divisioncausedabnormal MreB filament morphology

Sickle cell anemia ... a blood diseasecausesabnormal red blood cells

abnormal hemoglobincausingabnormal shaped erythrocytes

overexpressioncausesabnormal ER morphology

any drugcausingPLATELET MORPHOLOGY ABNORMAL

other drugscausePLATELET MORPHOLOGY ABNORMAL

which disorderscausewhich abnormal RBC shapes

the tumor(passive) caused byabnormal red blood cells

HEPARIN SODIUM INJECTIONcausesPLATELET MORPHOLOGY ABNORMAL

an intrinsic membrane protein defectleadsto abnormal RBC morphology

by loss or reduction of(passive) caused byAbnormal epidermal morphology

deficiency of lipids and vitamin Ecausingabnormal morphology of RBCs

Hemolysis in HS ... an intrinsic membrane protein defectleadsto abnormal RBC morphology

any drugcausingNEUTROPHIL MORPHOLOGY ABNORMAL

Vitamin Ecausingabnormal morphology of RBCs

a germline - dependent female sterile mutationcausingabnormal chorion morphology

any drugcausingLYMPHOCYTE MORPHOLOGY ABNORMAL

other drugscauseLYMPHOCYTE MORPHOLOGY ABNORMAL

abnormal megakaryocytescausingabnormal platelets

any drugcausingRED BLOOD CELL MORPHOLOGY ABNORMAL

the wnt-5 MO(passive) caused byabnormal islet morphology

fz-2 MO(passive) caused byabnormal islet morphology

loss of PGs , which cause reduced nuclear Fascin levelscausesabnormal nucleolar morphology

any drugcausingEOSINOPHIL MORPHOLOGY ABNORMAL

22 women in child bearing yearscausesabnormal rbc morphology

Genetic analysis ... 2 semi - dominant mutationscauseabnormal morphology

2 semi - dominant mutationscauseabnormal morphology

anemia(passive) may be caused byAbnormal RBCs

also(passive) are ... resultedRBC and platelet morphology

abnormal red blood cells morphology and possible causescausesabnormal red blood cells morphology and possible causes

abnormal red blood cells morphology and bite and blister cellscausesabnormal red blood cells morphology and bite and blister cells

to anemialeadingto anemia

the production of abnormal hemoglobin ( Hb ) , the oxygen - carrying component of the RBCcausethe production of abnormal hemoglobin ( Hb ) , the oxygen - carrying component of the RBC

a disorder(passive) caused bya disorder

to anaemialeadsto anaemia

The sickle shape(passive) is caused byThe sickle shape

to fusionleadingto fusion

a reticulocyte count , iron studies or tests for vitamin B12may prompta reticulocyte count , iron studies or tests for vitamin B12

increased red blood cell rigidity and hemolysiscauseincreased red blood cell rigidity and hemolysis

severe anemiacan causesevere anemia

chronic anemiacausingchronic anemia

to megaloblastic anemialeadingto megaloblastic anemia

from the diseaseresultfrom the disease

to megaloblastic anaemialeadingto megaloblastic anaemia

to anemia , pain , infection , and organ damagecan leadto anemia , pain , infection , and organ damage

in severe chronic anemiaresultingin severe chronic anemia

problemscan causeproblems

congenital forms of anemia(passive) caused bycongenital forms of anemia

a hemolytic anemia(passive) caused bya hemolytic anemia

a variety of complications , some of which are life threateningcan causea variety of complications , some of which are life threatening

a reticulocyte count , iron studies , tests for vitamin B12 and folate , G6PD , or hemoglobinopathy evaluation to help make a diagnosismay prompta reticulocyte count , iron studies , tests for vitamin B12 and folate , G6PD , or hemoglobinopathy evaluation to help make a diagnosis

a variety of complicationscan causea variety of complications

clotting in livercan causeclotting in liver

to a bleeding diathesismay leadto a bleeding diathesis

heart attacks or strokescould causeheart attacks or strokes

the spotscausingthe spots

types of anaemia(passive) caused bytypes of anaemia

in a heart attack or strokemay resultin a heart attack or stroke

from enhanced proliferation , reduced apoptosis and alterations in the differentiation patternresultedfrom enhanced proliferation , reduced apoptosis and alterations in the differentiation pattern

multiple infarcts(passive) caused bymultiple infarcts

the red blood cells to turn into crescent or sickle shapedcausesthe red blood cells to turn into crescent or sickle shaped

likelycauseslikely

from enhanced proliferationresultedfrom enhanced proliferation

the red blood cells to turn out to be crescent or sickle formedcausesthe red blood cells to turn out to be crescent or sickle formed

This condition(passive) is caused byThis condition

in their red blood cells being fragile , sticky and crescent - shaped ... i.e. , sickle shapedresultsin their red blood cells being fragile , sticky and crescent - shaped ... i.e. , sickle shaped

from various diseases , sickle cell anemia and many other anemia disorderscan also resultfrom various diseases , sickle cell anemia and many other anemia disorders

them to collapse within themselves ... resulting in the typical crescent shaped cells ... which are characteristic for the conditioncausesthem to collapse within themselves ... resulting in the typical crescent shaped cells ... which are characteristic for the condition

inflammatory diseases(passive) caused byinflammatory diseases

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