the disruption of CD40LG ... resulting in defective CD40L expression in the female patient with an extremely skewed X - inactivation pattern in T cells leading to the HIGM1 phenotype [ 17causedthe disruption of CD40LG ... resulting in defective CD40L expression in the female patient with an extremely skewed X - inactivation pattern in T cells leading to the HIGM1 phenotype [ 17

the so - called Philadelphia chromosome ( Ph(passive) is created bythe so - called Philadelphia chromosome ( Ph

a Mr 80,000 constitutively active tyrosine kinase protein , termed nucleophosminoriginatesa Mr 80,000 constitutively active tyrosine kinase protein , termed nucleophosmin

CML ... in which a piece of chromosome 9 containing the ABL1 oncogene is translocated to chromosome 22 and fused to the BCR gene(passive) is caused byCML ... in which a piece of chromosome 9 containing the ABL1 oncogene is translocated to chromosome 22 and fused to the BCR gene

in theshort arm of chromosome 1 ... band 3resultsin theshort arm of chromosome 1 ... band 3

in fusion of the Ewing sarcoma 1 ( EWS1 ) gene on chromosome 22 and WT1 on chromosome 11resultingin fusion of the Ewing sarcoma 1 ( EWS1 ) gene on chromosome 22 and WT1 on chromosome 11

h3createsh3

to fusion of depositsleadingto fusion of deposits

partial T18causespartial T18

to a kf protein with altered transcrip- tional propertiesleadingto a kf protein with altered transcrip- tional properties

to the transfer of the tyrosine kinase c - abl from chromosome 9 into the ber gene on chromosome 22leadsto the transfer of the tyrosine kinase c - abl from chromosome 9 into the ber gene on chromosome 22

in no net loss of genic material between daughter cellsresultsin no net loss of genic material between daughter cells

two abnormal chromosomes one elongated and longer chromosome 9 called “ derivative chromosome ” , and one shorted chromosome 22 called “ truncated chromosomecreatestwo abnormal chromosomes one elongated and longer chromosome 9 called “ derivative chromosome ” , and one shorted chromosome 22 called “ truncated chromosome

to fusion with AK6ledto fusion with AK6

pairing between two non - homologous chromosomes during meiosiswould causepairing between two non - homologous chromosomes during meiosis

in fusion of GOLGA5 with the RET oncogene found in radioactivity - induced thyroid carcinomasresultingin fusion of GOLGA5 with the RET oncogene found in radioactivity - induced thyroid carcinomas

in LRRFIP1-MET fusion in an atypical Spitz tumourresultingin LRRFIP1-MET fusion in an atypical Spitz tumour

to a terminal 6q duplication and partial monosomy of another chromosomeleadingto a terminal 6q duplication and partial monosomy of another chromosome

in the fusion of DGKG ( chromosome 3 ; light grey ) and BST1 ( chromosome 4 ; dark greyresultedin the fusion of DGKG ( chromosome 3 ; light grey ) and BST1 ( chromosome 4 ; dark grey

in a fusion of the EWS gene to the Fli1 generesultsin a fusion of the EWS gene to the Fli1 gene

in an elongated chromosome 9 ( 9q+resultingin an elongated chromosome 9 ( 9q+

irreversible aggregation and precipitationto preventirreversible aggregation and precipitation

reduced fertility in heterozygotes ( data not shown ; van Harten 1998causesreduced fertility in heterozygotes ( data not shown ; van Harten 1998

in a fusion with RARA gene encoding retinoic acid receptor alpharesultedin a fusion with RARA gene encoding retinoic acid receptor alpha

from double - strand breaks in both chromosomes 6 and 9 produced chromosomes 96 and 69resultingfrom double - strand breaks in both chromosomes 6 and 9 produced chromosomes 96 and 69

from the integration of GFP - tailswap T - DNAsoriginatingfrom the integration of GFP - tailswap T - DNAs

in the Philadelphia chromosome ( Ph1resultingin the Philadelphia chromosome ( Ph1

a fusion protein between the EWS gene on chromosome 22 and the FLI1 gene on chromosome 11createsa fusion protein between the EWS gene on chromosome 22 and the FLI1 gene on chromosome 11

in a RARα fusion protein and subsequent RARα functional impairment ( 25 , 26resultedin a RARα fusion protein and subsequent RARα functional impairment ( 25 , 26

binding between the promoter and RNA polymerasepreventedbinding between the promoter and RNA polymerase

in the EWSR1-ATF1 fusion generesultingin the EWSR1-ATF1 fusion gene

the A. thaliana chromosomes IV and V ( between AL6 and AL7creatingthe A. thaliana chromosomes IV and V ( between AL6 and AL7

in the fusion of EWS to an ETS transcription factorresultingin the fusion of EWS to an ETS transcription factor

in the formation of Philadelphia chromosomeresultingin the formation of Philadelphia chromosome

in diploid cellsresultingin diploid cells

to the Philadelphia chromosome ( Ph+ ) with a fusion gene BCR - ABL , the molecular hallmark of CML and Ph - positive acute lymphoblastic leukaemia ( LALleadingto the Philadelphia chromosome ( Ph+ ) with a fusion gene BCR - ABL , the molecular hallmark of CML and Ph - positive acute lymphoblastic leukaemia ( LAL

into the Philadelphia ( Ph ) chromosome and formation of the BCR / ABL fusion generesultinginto the Philadelphia ( Ph ) chromosome and formation of the BCR / ABL fusion gene

in a fusion of the PML protein to the retinoic acid receptor αresultingin a fusion of the PML protein to the retinoic acid receptor α

to the expression of the Bcr - Abl fusion proteinleadingto the expression of the Bcr - Abl fusion protein

in BCR - ABL1 kinase expressionresultingin BCR - ABL1 kinase expression